Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > ‘Fertility chip’ determines concentration and motility of semen

Abstract:
Loes Segerink, a researcher at UT's MESA+ Institute for Nanotechnology, has developed a "fertility chip" that can accurately count sperm and measure their motility. The chip can be inserted into a compact device for one-off use. A future home test kit will make it possible for men to test their sperm in a familiar environment. As a result, there is a greater chance of obtaining a correct diagnosis, also the method is simple and inexpensive. Segerink's doctoral defence will take place on 4 November 2011.

‘Fertility chip’ determines concentration and motility of semen

Enschede, The Netherlands | Posted on October 29th, 2011

Concentration and motility

The lab-on-a-chip developed by Segerink measures sperm concentration: the fertility standard states that a millilitre of ejaculate should contain at least 20 million sperm. A second important aspect of fertility is motility. This too can be measured using the lab-on-a-chip. Simple home test kits are already commercially available. These indicate whether the concentration is "above or below the standard value". These tests are too limited, however, as they do not give accurate concentration readings.

To swim or not to swim

Finally, sperm movement (motility) is another important measure of quality. A small adjustment of the lab-on-a-chip is all that is needed to sort motile sperm from non-motile sperm, after which both can be counted separately. By measuring sperm motility in this way, the chip offers a truly complete test.
How does it work

On the chip, sperm flow through a liquid-filled channel, beneath electrode "bridges". When a cell passes beneath one of these electrodes, there is a brief fluctuation in the electrical resistance. These events are counted. To test the reliability of her concentration measurements, Segerink added microspheres (tiny balls) to the liquid. Would the system only count sperm, or would it also register other particles? She found that the method was selective enough to distinguish sperm from microspheres. The system was also able to reliably distinguish white blood cells from other bodies. In addition to being an indicator of sperm quality, the white cell count provides important additional information to gynaecologists.

Partners

Segerink developed the "fertility chip" in the BIOS Lab-on-a-Chip research group of Prof. Albert van den Berg, in collaboration with the Twente Medical Spectrum. The research group is part of the MESA+ Institute for Nanotechnology of the University of Twente. Various companies (PigGenetics, Blue4Green, R&R Mechatronics, Menzis, and Lionix) also participated in this project, which was funded by the STW Technology Foundation in The Netherlands.

In 2011, Segerink received a Valorisation Grant, as a first step towards establishing a company. This will provide her with a platform for refining the fertility chip and its accompanying read-out device into a market-ready product.

####

For more information, please click here

Contacts:
Wiebe van der Veen
+31 (0)53 4894244

Copyright © University of Twente

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Lab-on-a-chip

Waterloo, Technion Partner to Advance Research, Commercialization March 19th, 2014

In vitro innovation: Testing nanomedicine with blood cells on a microchip February 4th, 2014

Researchers model macroscale plasmonic convection to control fluid and particle motion January 22nd, 2014

SiMPore Collaboration Leads to Development of Novel Chip-Sized Pump November 7th, 2013

Chip Technology

'Exotic' material is like a switch when super thin April 18th, 2014

Scientists open door to better solar cells, superconductors and hard-drives: Research enhances understanding of materials interfaces April 14th, 2014

Obducat has launched a new generation of SINDRE® Nano Imprint production system April 11th, 2014

Scientists in Singapore develop novel ultra-fast electrical circuits using light-generated tunneling currents April 10th, 2014

Nanomedicine

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

High-temperature plasmonics eyed for solar, computer innovation April 17th, 2014

Discoveries

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

'Exotic' material is like a switch when super thin April 18th, 2014

Announcements

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Research partnerships

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds April 17th, 2014

Scientists Capture Ultrafast Snapshots of Light-Driven Superconductivity: X-rays reveal how rapidly vanishing 'charge stripes' may be behind laser-induced high-temperature superconductivity April 16th, 2014

Scalable CVD process for making 2-D molybdenum diselenide: Rice, NTU scientists unveil CVD production for coveted 2-D semiconductor April 8th, 2014

Carbon nanotubes grow in combustion flames April 1st, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE