Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > ‘Fertility chip’ determines concentration and motility of semen

Abstract:
Loes Segerink, a researcher at UT's MESA+ Institute for Nanotechnology, has developed a "fertility chip" that can accurately count sperm and measure their motility. The chip can be inserted into a compact device for one-off use. A future home test kit will make it possible for men to test their sperm in a familiar environment. As a result, there is a greater chance of obtaining a correct diagnosis, also the method is simple and inexpensive. Segerink's doctoral defence will take place on 4 November 2011.

‘Fertility chip’ determines concentration and motility of semen

Enschede, The Netherlands | Posted on October 29th, 2011

Concentration and motility

The lab-on-a-chip developed by Segerink measures sperm concentration: the fertility standard states that a millilitre of ejaculate should contain at least 20 million sperm. A second important aspect of fertility is motility. This too can be measured using the lab-on-a-chip. Simple home test kits are already commercially available. These indicate whether the concentration is "above or below the standard value". These tests are too limited, however, as they do not give accurate concentration readings.

To swim or not to swim

Finally, sperm movement (motility) is another important measure of quality. A small adjustment of the lab-on-a-chip is all that is needed to sort motile sperm from non-motile sperm, after which both can be counted separately. By measuring sperm motility in this way, the chip offers a truly complete test.
How does it work

On the chip, sperm flow through a liquid-filled channel, beneath electrode "bridges". When a cell passes beneath one of these electrodes, there is a brief fluctuation in the electrical resistance. These events are counted. To test the reliability of her concentration measurements, Segerink added microspheres (tiny balls) to the liquid. Would the system only count sperm, or would it also register other particles? She found that the method was selective enough to distinguish sperm from microspheres. The system was also able to reliably distinguish white blood cells from other bodies. In addition to being an indicator of sperm quality, the white cell count provides important additional information to gynaecologists.

Partners

Segerink developed the "fertility chip" in the BIOS Lab-on-a-Chip research group of Prof. Albert van den Berg, in collaboration with the Twente Medical Spectrum. The research group is part of the MESA+ Institute for Nanotechnology of the University of Twente. Various companies (PigGenetics, Blue4Green, R&R Mechatronics, Menzis, and Lionix) also participated in this project, which was funded by the STW Technology Foundation in The Netherlands.

In 2011, Segerink received a Valorisation Grant, as a first step towards establishing a company. This will provide her with a platform for refining the fertility chip and its accompanying read-out device into a market-ready product.

####

For more information, please click here

Contacts:
Wiebe van der Veen
+31 (0)53 4894244

Copyright © University of Twente

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Light pulses control graphene's electrical behavior: Finding could allow ultrafast switching of conduction, and possibly lead to new broadband light sensors August 1st, 2014

President Obama Meets U.S. Laureates of 2014 Kavli Prizes August 1st, 2014

Stanford researchers seek 'Holy Grail' in battery design: Pure lithium anode closer to reality with development of protective layer of interconnected carbon domes August 1st, 2014

Air Force’s 30-year plan seeks 'strategic agility' August 1st, 2014

Lab-on-a-chip

EPFL Scientists use nanoscale IR spectroscopy to demonstrate α to β secondary structure transition associated with amyloid formation June 10th, 2014

Fully automated DNA lab-on-a-chip microfluidic system wins Dolomite’s Productizing Science® competition 2013 June 10th, 2014

One small chip -- one giant leap forward for early cancer detection: An ultra-sensitive nano-chip capable of detecting cancer at early stages May 19th, 2014

A Lab in Your Pocket May 7th, 2014

Chip Technology

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Nanometrics Reports Second Quarter 2014 Financial Results July 30th, 2014

A*STAR and industry form S$200M semiconductor R&D July 25th, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Nanomedicine

Taking the guesswork out of cancer therapy: New molecular test kit predicts patient’s survival and drug response August 1st, 2014

Arrowhead to Report Fiscal 2014 Third Quarter Financial Results- Conference Call Scheduled for Tuesday, August 12, 2014 - July 31st, 2014

New imaging agent provides better picture of the gut July 30th, 2014

Zenosense, Inc. July 29th, 2014

Discoveries

Iranian Scientists Produce Cobalt–Alumina Ceramic Nano Inks August 1st, 2014

Light pulses control graphene's electrical behavior: Finding could allow ultrafast switching of conduction, and possibly lead to new broadband light sensors August 1st, 2014

Taking the guesswork out of cancer therapy: New molecular test kit predicts patient’s survival and drug response August 1st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Announcements

Light pulses control graphene's electrical behavior: Finding could allow ultrafast switching of conduction, and possibly lead to new broadband light sensors August 1st, 2014

President Obama Meets U.S. Laureates of 2014 Kavli Prizes August 1st, 2014

Stanford researchers seek 'Holy Grail' in battery design: Pure lithium anode closer to reality with development of protective layer of interconnected carbon domes August 1st, 2014

Air Force’s 30-year plan seeks 'strategic agility' August 1st, 2014

Research partnerships

Study finds physical link to strange electronic behavior: Neutron measurements offer new clues about iron-based superconductor July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

New imaging agent provides better picture of the gut July 30th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE