Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > SiMPore Awarded Phase I SBIR From NIH To Improve TEM Imaging Technology For Biomedical Researchers

Abstract:
SiMPore Inc., an early-stage nanotechnology company in Rochester, NY, has received a Phase I SBIR grant from the National Institutes of Health to improve phase contrast transmission electron microscopy (TEM). An electron microscope uses a beam of electrons instead of light to illuminate an object of interest. It allows the object to be observed at one-million-times magnification or greater. In theory, this level of magnification should permit biomedical researchers to see the three-dimensional structure of a virus or similarly sized biological molecule. However, current TEM methods are limited in certain aspects. Phase contrast promises to overcome some of these inherent limitations of TEM imaging of biological structures.

SiMPore Awarded Phase I SBIR From NIH To Improve TEM Imaging Technology For Biomedical Researchers

Rochester, NY | Posted on September 29th, 2011

The technology that SiMPore develops will increase the practicality of phase-contrast TEM to image biological molecules. By fabricating next generation phase plates, a core component of phase-contrast TEM, SiMPore hopes to increase the practical accessibility of this method. SiMPore will apply its expertise in the fabrication of thin-films to create a new class of highly manufacturable phase plates.

The grant application elicited both high scores and favorable compliments from NIH reviewers. The reviewers unanimously acknowledged that the proposed work addresses an unmet need, is highly innovative and greatly significant. They also recognized that the proposal could have a high-degree of immediate impact on the field of electron microscopy.

Dr. Christopher Striemer, Vice-President of Membrane Development at SiMPore, said, "We believe several key factors contributed to the success of our application. Our expertise in thin-film micro-fabrication, combined with the electron microscopy expertise of our collaborator, and a clear market need for these components, provided a strong basis for our proposal. Our case was very compelling."

SiMPore will collaborate with the New York State Department of Health's Wadsworth Center, which will test the phase plates SiMPore develops. Mr. Michael Marko of the Wadsworth Center, a recognized expert in the use of phase plates, will direct the evaluation of SiMPore's prototypes. Mr. Marko has developed several first-in-class innovations in phase-contrast electron microscopy.

####

About SiMPore Inc.
SiMPore is commercializing a novel membrane technology enabling new discoveries while also reducing the time and cost of everyday development processes in the life sciences. SiMPore is a Rochester, New York-based nanotechnology company that designs and produces membranes and membrane-enabled products based on its unique patent-pending platform technology - the UltraSMŽ ultrathin nanoporous silicon membrane. The UltraSMŽ membrane is the world's first membrane to offer both tunable nanometer-scale thickness and pore size. SiMPore is developing products that take advantage of these one-of-a-kind features, including filters for separating and concentrating biological molecules and nanoparticles, cell culture substrates for growing cells, and electron microscopy grids for preparing and imaging samples at the nanoscale.

About TEMwindows.com

TEMwindows.com, a division of SiMPore Inc., is the online source of innovative sample preparation solutions for the imaging and analysis of nanoscale materials. TEMwindows.com features state-of-the-art transmission electron microscopy windows that enable researchers to characterize their cutting-edge nanomaterials. By incorporating the latest MEMS and thin film technologies, TEMwindows.com provides researchers with the resources to advance their research and development programs. TEMwindows.com is fully integrated with, and supported by, the technical expertise at SiMPore.

UltraSM is a registered trademark of SiMPore Inc.

For more information, please click here

Contacts:
Dr. Christopher Striemer
Vice-President
Membrane Development

Copyright © SiMPore Inc.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Imaging

Thin films offer promise for ferroelectric devices: Researchers at Tokyo Institute of Technology demystify the ferroelectric properties observed in hafnium-oxide-based thin films, revealing a potentially useful device material August 3rd, 2015

Take a trip through the brain July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

Govt.-Legislation/Regulation/Funding/Policy

Vaccine with virus-like nanoparticles effective treatment for RSV, study finds August 3rd, 2015

MIPT researchers clear the way for fast plasmonic chips August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Announcements

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Tools

Thin films offer promise for ferroelectric devices: Researchers at Tokyo Institute of Technology demystify the ferroelectric properties observed in hafnium-oxide-based thin films, revealing a potentially useful device material August 3rd, 2015

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Take a trip through the brain July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project