Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > The Nanoscopy Group of Dr Volker Deckert applies JPK platform of optical technologies in the development of TERS

Dr Marc Richter, user of the JPK NanoWizard® system at the IPHT, Jena
Dr Marc Richter, user of the JPK NanoWizard® system at the IPHT, Jena

Abstract:
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research and technique development activities of the Institute of Photonic Technology (IPHT) in Jena under the direction of Dr Volker Deckert.

The Nanoscopy Group of Dr Volker Deckert applies JPK platform of optical technologies in the development of TERS

Berlin, Germany | Posted on September 27th, 2011

At the Institute of Photonic Technology (IPHT) in Jena, light is the central focus of research and development. The new IPHT sees photonics as the most important key technology of the 21st century. It is guaranteed to play a leading role in the fields of information technology and communications, security, material science, life science and health.

Dr Volker Deckert is the head of the Nanoscopy department which utilizes instrumental methods in the development of molecular spectroscopic methods with the highest spatial resolution. Central to this program has been the use of tip-enhanced Raman scattering, TERS, where JPK's NanoWizard® systems and Tip-Assisted Optics module have provided a platform in the development of these experimental methods. In many cases, the structural sizes of components are below the capabilities of normal optical microscopic or spectroscopic techniques. Optical near-field microscopy in combination with Raman spectroscopy pushes the achievable resolution significantly below the diffraction limit of standard instruments. The goal of their work is the advancement of TERS to become an accessible and sensitive tool for the analysis of surfaces and boundaries under ambient conditions. Applications are carefully selected. For example, heterogeneous catalytic reactions are studied because such application-oriented experiments may be used to verify and improve the functionality of the instrument and to demonstrate its practicality for "real" problems.

Recent examples from the literature include a paper published in SMALL, January 2011, which reported Nanometer-Sized Lipid and Protein Domains on a Single Cell. Their existence was confirmed with highly resolved lateral images combined with direct spectroscopic evidence. TERS was used as a label-free, nondestructive method for the direct mapping of nano¬meter-sized lipid and protein domains on the surface of a single cell. Spectral processing allowed the analysis and visualization of the different cellular surface components down to a spatial resolution of 10-20 nm.

Another excellent example of this technique in action was published in the Journal of Biophotonics, June 2010. Here, biochemical imaging below the diffraction limit was demonstrated with the cellular membrane being probed in relation to other structures using TERS. First, a vibrational mapping on the nanometer scale was performed on a protein- (streptavidin) labeled & supported phospholipid film using TERS. In this instance, a TERS spectral map was measured on the biomembrane model using a step size far below the diffraction limit. Considering the model composition, spectra were classified as either typical for lipids, proteins or both simultaneously in a qualitative manner. Subsequently, the spectroscopic information was assigned with respect to the topographic features. Since a spatial differentiation between different compositional domains is difficult to achieve by topographic features only, the combination of morphology and spectral data enables a much more detailed characterization of biomembranes.

Commenting on his interactions with JPK over the years, Dr Deckert said "Since 2002, all our TERS experiments relied on instruments based on JPK AFMs. In particular, the joint development coupling and synchronizing both the spectroscopy and scanning probe parts proved to be extremely robust and reliable. JPK's support was fast and thorough whenever a specific adaption to a new Raman microscope or detection scheme was required."

Working with Dr Deckert has been of great help to JPK Founder and CTO, Torsten Jähnke. Speaking recently in Berlin, Jähnke said "The development of TERS required a tip-scanning system with ready-access to the optics and the multiple electronic signal possibilities. Understanding Dr Deckert's needs have helped us build in the required versatility and flexibility in the development of our latest systems culminating in the announcement of our new NanoWizard®3 NanoOptics system."

JPK develop, engineer and manufacture instrumentation in Germany to the world-recognized standards of German precision engineering, quality and functionality. For further details of the NanoWizard® AFM and other products in the JPK family of bio and nanoscale instrumentation, please visit the JPK web site (www.jpk.com) or Facebook (www.jpk.com/facebook).

####

About JPK Instruments (JPK)
JPK Instruments AG is a world-leading manufacturer of nanoanalytic instruments - particularly atomic force microscope (AFM) systems and optical tweezers - for a broad range of applications reaching from soft matter physics to nano-optics, from surface chemistry to cell and molecular biology. From its earliest days applying atomic force microscope (AFM) technology, JPK has recognized the opportunities provided by nanotechnology for transforming life sciences and soft matter research. This focus has driven JPK’s success in uniting the worlds of nanotechnology tools and life science applications by offering cutting-edge technology and unique applications expertise. Headquartered in Berlin and with direct operations in Dresden, Cambridge (UK), Singapore, Tokyo (Japan) and Paris (France), JPK maintains a global network of distributors and support centers and provides on the spot applications and service support to an ever-growing community of researchers.

For more information, please click here

Contacts:
Jezz Leckenby
NetDyaLog Limited
T: +44 (0) 1799 521881
M: +44 (0) 7843 012997

or
Claudia Boettcher
JPK Instruments
T: +49 (0) 30 5331 12070

Copyright © JPK Instruments (JPK)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Imaging

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

News and information

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

PETA science consortium to present hazard testing strategy at nanotoxicology meeting: High tech field ripe for use of sophisticated non-animal testing strategies April 22nd, 2014

Harris & Harris Group Notes the Receipt of Proceeds From the Sale of Molecular Imprints' Semiconductor Business to Canon April 22nd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Announcements

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

PETA science consortium to present hazard testing strategy at nanotoxicology meeting: High tech field ripe for use of sophisticated non-animal testing strategies April 22nd, 2014

Harris & Harris Group Notes the Receipt of Proceeds From the Sale of Molecular Imprints' Semiconductor Business to Canon April 22nd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Tools

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Oxford Instruments Asylum Research Introduces the MFP-3D InfinityTM AFM Featuring Powerful New Capabilities and Stunning High Performance April 18th, 2014

More effective kidney stone treatment, from the macroscopic to the nanoscale April 17th, 2014

Aerotech X-Y ball-screw stage for economical high performance Planar positioning April 16th, 2014

Photonics/Optics/Lasers

High-temperature plasmonics eyed for solar, computer innovation April 17th, 2014

Scientists Capture Ultrafast Snapshots of Light-Driven Superconductivity: X-rays reveal how rapidly vanishing 'charge stripes' may be behind laser-induced high-temperature superconductivity April 16th, 2014

Lumerical files a provisional patent that extends the standard eigenmode expansion propagation technique to better address waveguide component design. Lumerical’s EME propagation tool will address a wide set of waveguide applications in silicon photonics and integrated optics April 16th, 2014

Near-field Nanophotonics Workshop in Boston April 14th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE