Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Searching for breast cancer metastasis without radiation

Abstract:
Researchers from the MIRA research institute at the University of Twente, together with their research partners, have been awarded a €1.4 million grant to develop a new method of determining whether patients with breast cancer have developed secondary tumours. Instead of potentially dangerous radioactive particles, the new method uses harmless magnetic nanoparticles and an advanced ultrasensitive ‘metal detector'.

Searching for breast cancer metastasis without radiation

The Netherlands | Posted on July 16th, 2011

Around thirteen thousand women in the Netherlands are diagnosed with breast cancer every year. For a large proportion of these patients, a so-called sentinel node procedure is used to determine whether the cancer had spread. In this procedure radioactive particles are introduced into the body, so it can be seen whether the cancer has spread to the lymph nodes in the armpits; the place where any spreading of breast cancer always takes place first. However, the method has a number of drawbacks. The limited storage life of the radioactive particles creates a logistic problem, for example, which means that the procedure cannot be carried out at any place or time. Worldwide this is even the reason why only half of breast cancer patients can undergo the procedure. What is more, the radioactivity represents a health risk for both patients and medical personnel.

Advanced metal detector

Another method for tracing the spread of cancer cells is with the use of magnetic nanoparticles. These nanoparticles are introduced into the body, and can be traced using a magnetic detection system; essentially an advanced ‘metal detector'. However, existing detectors are not sensitive enough to measure the difference between the background noise and the signal of the nanoparticles.

180 degrees below zero

Researchers from the University of Twente will therefore be developing a more sensitive method for detecting the magnetic materials: a cryomagnetic detection system. By fitting the system with a compact sensor antenna, which is cooled to 180 degrees below zero, it is possible to greatly improve the signal-to-noise ratio.

The nanoparticles have already been used in clinical applications, for example as contrast material for MRI scans, so their efficacy and safety have already been demonstrated. The main advantage of using the nanoparticles, in contrast to radioactive particles, is that they basically have an unlimited storage life, and so they can be used at any place and time. They also do not present any health risk for patients or medical personnel.

Project partners

The research into the possibilities of a cryomagnetic detection system is being carried out by the NeuroIMaging research group of the MIRA research institute at the University of Twente. Dr Bennie ten Haken is the project coordinator.

The University of Twente researchers are working in close collaboration with the university's spin-off business Kryoz Technologies BV, Panton BV, DKMS BV, Radboud University Nijmegen Medical Centre and the Medisch Spectrum Twente hospital. The total cost of the project will be around €3 million. €1.4 million of this total will be provided in grants from NL Agency and the Dutch provinces of Overijssel and Gelderland. The research project will last for four years. The researchers expect that by 2015 they will be able to show whether the method is truly suitable for clinical applications.

####

For more information, please click here

Contacts:
Wiebe van der Veen
+31612185692

Copyright © AlphaGalileo

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Amorphous Coordination Polymer Particles as alternative to classical nanoplatforms for nanomedicine October 30th, 2014

Tiny carbon nanotube pores make big impact October 29th, 2014

Microrockets fueled by water neutralize chemical and biological warfare agents October 29th, 2014

Nanosafety research – there’s room for improvement October 29th, 2014

Nanomedicine

Amorphous Coordination Polymer Particles as alternative to classical nanoplatforms for nanomedicine October 30th, 2014

'Electronic skin' could improve early breast cancer detection October 29th, 2014

Tiny carbon nanotube pores make big impact October 29th, 2014

New nanodevice to improve cancer treatment monitoring October 27th, 2014

Announcements

Amorphous Coordination Polymer Particles as alternative to classical nanoplatforms for nanomedicine October 30th, 2014

Tiny carbon nanotube pores make big impact October 29th, 2014

Microrockets fueled by water neutralize chemical and biological warfare agents October 29th, 2014

Nanosafety research – there’s room for improvement October 29th, 2014

Research partnerships

Sussex physicists find simple solution for quantum technology challenge October 28th, 2014

Molecular beacons shine light on how cells 'crawl' October 27th, 2014

New evidence for an exotic, predicted superconducting state October 27th, 2014

Breakthrough in molecular electronics paves the way for DNA-based computer circuits in the future: DNA-based programmable circuits could be more sophisticated, cheaper and simpler to make October 27th, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE