Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > Press > Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue

Optical images of polyethylene glycol scaffolds expanding in response to stretching.(Note: green tone added to image.)Image credit: UC San Diego / Shaochen Chen
Optical images of polyethylene glycol scaffolds expanding in response to stretching.(Note: green tone added to image.)
Image credit: UC San Diego / Shaochen Chen

Abstract:
A new biomaterial designed for repairing damaged human tissue doesn't wrinkle up when it is stretched. The invention from nanoengineers at the University of California, San Diego marks a significant breakthrough in tissue engineering because it more closely mimics the properties of native human tissue.

Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue

San Diego | Posted on May 27th, 2011

Shaochen Chen, professor in the Department of NanoEngineering at the UC San Diego Jacobs School of Engineering, hopes future tissue patches, which are used to repair damaged heart walls, blood vessels and skin, for example, will be more compatible with native human tissue than the patches available today. His findings were published in a recent issue of the journal Advanced Functional Materials.

The new biomaterial was created using a new biofabrication platform that Chen is developing under a four-year, $1.5 million grant from the National Institutes of Health. This biofabrication technique uses light, precisely controlled mirrors and a computer projection system -- shined on a solution of new cells and polymers -- to build three-dimensional scaffolds with well-defined patterns of any shape for tissue engineering.

"We are also exploring other opportunities," said Chen. "It's a new material. I think it's just a matter of time before more people will pick up and find applications for it in defense, energy and communications, for instance."

Although Chen's team is focused on creating biological materials, he said the manufacturing technology could be used to engineer many other kinds of materials including metal parts used in ships and spacecraft, for example.

Shape turned out to be essential to the new material's mechanical property. While most engineered tissue is layered in scaffolds that take the shape of circular or square holes, Chen's team created two new shapes called "reentrant honeycomb" and "cut missing rib." Both shapes exhibit the property of negative Poisson's ratio (i.e. not wrinkling when stretched) and maintain this property whether the tissue patch has one or multiple layers. One layer is double the thickness of a human hair, and the number of layers used in a tissue patch depends on the thickness of the native tissue that doctors are trying to repair. A single layer would not be thick enough to repair a heart wall or skin tissue, for example. The next phase of research will involve working with the Department of Bioengineering at the Jacobs School of Engineering to make tissue grafts to repair damaged blood vessels.

The team includes postdoctoral researchers in multiple disciplines: David Fozdar with the University of Texas at Austin, Department of Mechanical Engineering; Li-Hsin Han with the Stanford University School of Medicine, Department of Orthopeadic Surgery; and Pranav Soman and Jim Woo Lee at the UCSD Jacobs School of Engineering Department of NanoEngineering.

####

For more information, please click here

Contacts:
Catherine Hockmuth
858-822-1359

Copyright © University of California, San Diego

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Marine/Watercraft

Novel anti-biofilm nano coating developed at Ben-Gurion U.: Offers significant anti-adhesive potential for a variety of medical and industrial applications April 25th, 2016

Highlights from the Graphene Flagship April 22nd, 2016

Computer simulation discloses new effect of cavitation: Steam bubbles in fast flowing fluids obviously also result from chemical surface properties; use for reducing wear in pumps and plain bearings March 29th, 2016

Drexel researchers roll out new method for making the invisible brushes that repel dirt: Polymer crystal 'turf' improves nanobrush-making process March 24th, 2016

Nanomedicine

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Pixel-array quantum cascade detector paves the way for portable thermal imaging devices: Research team from TU-Wien Center for Micro- and Nanostructures have developed a new 'cooler' sensing instrument thereby increasing energy-efficiency and enhancing mobility for diagnostic tes July 28th, 2016

Starpharma initiates new DEPô drug delivery program with AstraZeneca July 27th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Discoveries

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Materials/Metamaterials

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

WSU researchers 'watch' crystal structure change in real time: Breakthrough made possible by new Argonne facility July 27th, 2016

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Announcements

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Aerospace/Space

Scientists move 1 step closer to creating an invisibility cloak July 15th, 2016

Bouncing droplets remove contaminants like pogo jumpers: Researchers at Duke University and the University of British Columbia are exploring whether surfaces can shed dirt without being subjected to fragile coatings July 7th, 2016

Russian physicists create a high-precision 'quantum ruler': Physicists have devised a method for creating a special quantum entangled state June 25th, 2016

Novel capping strategy improves stability of perovskite nanocrystals: Study addresses instability issues with organometal-halide perovskites, a promising class of materials for solar cells, LEDs, and other applications June 13th, 2016

Nanobiotechnology

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Starpharma initiates new DEPô drug delivery program with AstraZeneca July 27th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Accurate design of large icosahedral protein nanocages pushes bioengineering boundaries: Scientists used computational methods to build ten large, two-component, co-assembling icosahedral protein complexes the size of small virus coats July 25th, 2016

Research partnerships

Lonely atoms, happily reunited July 29th, 2016

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

Quantum drag:University of Iowa physicist says current in one iron magnetic sheet can create quantized spin waves in another, separate sheet July 22nd, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic