Home > Press > Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue
 |
Optical images of polyethylene glycol scaffolds expanding in response to stretching.(Note: green tone added to image.) Image credit: UC San Diego / Shaochen Chen |
Abstract:
A new biomaterial designed for repairing damaged human tissue doesn't wrinkle up when it is stretched. The invention from nanoengineers at the University of California, San Diego marks a significant breakthrough in tissue engineering because it more closely mimics the properties of native human tissue.
Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue
San Diego | Posted on May 27th, 2011
Shaochen Chen, professor in the Department of NanoEngineering at the UC San Diego Jacobs School of Engineering, hopes future tissue patches, which are used to repair damaged heart walls, blood vessels and skin, for example, will be more compatible with native human tissue than the patches available today. His findings were published in a recent issue of the journal Advanced Functional Materials.
The new biomaterial was created using a new biofabrication platform that Chen is developing under a four-year, $1.5 million grant from the National Institutes of Health. This biofabrication technique uses light, precisely controlled mirrors and a computer projection system -- shined on a solution of new cells and polymers -- to build three-dimensional scaffolds with well-defined patterns of any shape for tissue engineering.
"We are also exploring other opportunities," said Chen. "It's a new material. I think it's just a matter of time before more people will pick up and find applications for it in defense, energy and communications, for instance."
Although Chen's team is focused on creating biological materials, he said the manufacturing technology could be used to engineer many other kinds of materials including metal parts used in ships and spacecraft, for example.
Shape turned out to be essential to the new material's mechanical property. While most engineered tissue is layered in scaffolds that take the shape of circular or square holes, Chen's team created two new shapes called "reentrant honeycomb" and "cut missing rib." Both shapes exhibit the property of negative Poisson's ratio (i.e. not wrinkling when stretched) and maintain this property whether the tissue patch has one or multiple layers. One layer is double the thickness of a human hair, and the number of layers used in a tissue patch depends on the thickness of the native tissue that doctors are trying to repair. A single layer would not be thick enough to repair a heart wall or skin tissue, for example. The next phase of research will involve working with the Department of Bioengineering at the Jacobs School of Engineering to make tissue grafts to repair damaged blood vessels.
The team includes postdoctoral researchers in multiple disciplines: David Fozdar with the University of Texas at Austin, Department of Mechanical Engineering; Li-Hsin Han with the Stanford University School of Medicine, Department of Orthopeadic Surgery; and Pranav Soman and Jim Woo Lee at the UCSD Jacobs School of Engineering Department of NanoEngineering.
####
For more information, please click here
Contacts:
Catherine Hockmuth
858-822-1359
Copyright © University of California, San Diego
If you have a comment, please
Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
News and information
Aspen Aerogels Announces $22.5 Million Private Placement May 18th, 2013
NanoInk, Inc. Assets To Be Sold May 18th, 2013
Beautiful "flowers" self-assemble in a beaker: Elaborate nanostructures blossom from a chemical reaction perfected at Harvard May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013
Marine/Watercraft
Improving Energy Storage: Neutron Scattering Technique Provides New Data on Adsorption of Ions in Microporous Materials February 28th, 2013
Southampton scientist develops strongest, lightest glass nanofibres in the world January 10th, 2013
Research and Markets: The Global Nanotechnology and Nanomaterials Industry 2013 Report: Stage of Development, Global Activity and Market Opportunities December 16th, 2012
mPhase to Release Video of New Product October 25th, 2012
Nanomedicine
Nanotechnology could help fight diabetes: Injectable nanogel can monitor blood-sugar levels and secrete insulin when needed May 16th, 2013
Nanobiotix Revenue for the 1st quarter of 2013 May 15th, 2013
Pitt Chemists Demonstrate Nanoscale Alloys So Bright They Could Have Potential Medical Applications: “Think about a particle that will not only help researchers detect cancer sooner but be used to treat the tumor, too.” May 15th, 2013
Using clay to grow bone: Researchers use synthetic silicate to stimulate stem cells into bone cells May 15th, 2013
Discoveries
Beautiful "flowers" self-assemble in a beaker: Elaborate nanostructures blossom from a chemical reaction perfected at Harvard May 17th, 2013
Artificial Forest for Solar Water-Splitting: Berkeley Lab Researchers Report First Fully Integrated Artificial Photosynthesis Nanosystem May 17th, 2013
Moth-Inspired Nanostructures Take the Color Out of Thin Films May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013
Materials
Advancements and developments of solid-state nanopores sensors May 16th, 2013
Physicists discover a new kind of friction: Friction in the nano-world May 16th, 2013
Squishy hydrogels may be the ticket for studying biological effects of nanoparticles May 15th, 2013
Pitt Chemists Demonstrate Nanoscale Alloys So Bright They Could Have Potential Medical Applications: “Think about a particle that will not only help researchers detect cancer sooner but be used to treat the tumor, too.” May 15th, 2013
Announcements
Aspen Aerogels Announces $22.5 Million Private Placement May 18th, 2013
NanoInk, Inc. Assets To Be Sold May 18th, 2013
NIA Public Briefing: Nanotechnology and the Council of Europe May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013
Aerospace/Space
Moth-Inspired Nanostructures Take the Color Out of Thin Films May 17th, 2013
Lifeboat publishes its first book: The Lifeboat Foundation has published its first book, "The Human Race to the Future: What Could Happen -- and What to Do" May 14th, 2013
UC Santa Barbara History Professor's Book Elucidates, Celebrates ‘Visioneers' May 14th, 2013
Over 20 Exhibitors To Present At International Space Development Conference May 13th, 2013
Nanobiotechnology
Artificial Forest for Solar Water-Splitting: Berkeley Lab Researchers Report First Fully Integrated Artificial Photosynthesis Nanosystem May 17th, 2013
Glowing Plant Kickstarter Project Retains Digital Marketing Agency, Command Partners: Glowing Plant brings on top Charlotte-based digital marketing firm to assist in crowdfunding campaign May 16th, 2013
DNA-Guided Assembly Yields Novel Ribbon-Like Nanostructures: Approach could be useful in fabricating new kinds of materials with engineered properties May 16th, 2013
Advancements and developments of solid-state nanopores sensors May 16th, 2013
Research partnerships
Advancements and developments of solid-state nanopores sensors May 16th, 2013
Imec and Renesas collaborate on ultra-low power short range radios: Collaboration will develop robust wireless solutions for future electronics May 16th, 2013
Silex Microsystems Joins ENIAC Project PROMINENT To Bring Flexible and Cost Effective Inkjet Technologies to the MEMS Manufacturing Process: Silex Will Develop New Solutions for Through-Silicon Via Manufacture and Hermetic Wafer Bonding May 13th, 2013
Cold atoms for quantum technology May 12th, 2013