Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue

Optical images of polyethylene glycol scaffolds expanding in response to stretching.(Note: green tone added to image.)Image credit: UC San Diego / Shaochen Chen
Optical images of polyethylene glycol scaffolds expanding in response to stretching.(Note: green tone added to image.)
Image credit: UC San Diego / Shaochen Chen

Abstract:
A new biomaterial designed for repairing damaged human tissue doesn't wrinkle up when it is stretched. The invention from nanoengineers at the University of California, San Diego marks a significant breakthrough in tissue engineering because it more closely mimics the properties of native human tissue.

Nanoengineers Invent New Biomaterial That More Closely Mimics Human Tissue

San Diego | Posted on May 27th, 2011

Shaochen Chen, professor in the Department of NanoEngineering at the UC San Diego Jacobs School of Engineering, hopes future tissue patches, which are used to repair damaged heart walls, blood vessels and skin, for example, will be more compatible with native human tissue than the patches available today. His findings were published in a recent issue of the journal Advanced Functional Materials.

The new biomaterial was created using a new biofabrication platform that Chen is developing under a four-year, $1.5 million grant from the National Institutes of Health. This biofabrication technique uses light, precisely controlled mirrors and a computer projection system -- shined on a solution of new cells and polymers -- to build three-dimensional scaffolds with well-defined patterns of any shape for tissue engineering.

"We are also exploring other opportunities," said Chen. "It's a new material. I think it's just a matter of time before more people will pick up and find applications for it in defense, energy and communications, for instance."

Although Chen's team is focused on creating biological materials, he said the manufacturing technology could be used to engineer many other kinds of materials including metal parts used in ships and spacecraft, for example.

Shape turned out to be essential to the new material's mechanical property. While most engineered tissue is layered in scaffolds that take the shape of circular or square holes, Chen's team created two new shapes called "reentrant honeycomb" and "cut missing rib." Both shapes exhibit the property of negative Poisson's ratio (i.e. not wrinkling when stretched) and maintain this property whether the tissue patch has one or multiple layers. One layer is double the thickness of a human hair, and the number of layers used in a tissue patch depends on the thickness of the native tissue that doctors are trying to repair. A single layer would not be thick enough to repair a heart wall or skin tissue, for example. The next phase of research will involve working with the Department of Bioengineering at the Jacobs School of Engineering to make tissue grafts to repair damaged blood vessels.

The team includes postdoctoral researchers in multiple disciplines: David Fozdar with the University of Texas at Austin, Department of Mechanical Engineering; Li-Hsin Han with the Stanford University School of Medicine, Department of Orthopeadic Surgery; and Pranav Soman and Jim Woo Lee at the UCSD Jacobs School of Engineering Department of NanoEngineering.

####

For more information, please click here

Contacts:
Catherine Hockmuth
858-822-1359

Copyright © University of California, San Diego

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Promising results obtained with a new electrocatalyst that reduces the need for platinum: Researchers from Aalto University have succeeded in manufacturing electrocatalysts used for storing electric energy with one-hundredth of the amount of platinum that is usually needed March 24th, 2017

Leti Presents Advances in Propagation Modeling and Antenna Design for mmWave Spectrum: Paper Is One of 15 that Leti Presented at European Conference on Antennas and Propagation March 19-24 March 23rd, 2017

Rice U. refines filters for greener natural gas: New study defines best materials for carbon capture, methane selectivity March 23rd, 2017

Marine/Watercraft

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Transparent gel-based robots can catch and release live fish: Made from hydrogel, robots may one day assist in surgical operations, evade underwater detection February 2nd, 2017

NIST-made 'sun and rain' used to study nanoparticle release from polymers October 5th, 2016

New material to revolutionize water proofing September 12th, 2016

Nanomedicine

Nanobiotix: The Independent Data Monitoring Committee Recommends the Continuation of the Ongoing Phase II/III Trial of NBTXR3 in Soft Tissue Sarcoma March 23rd, 2017

Nanoparticle paves the way for new triple negative breast cancer drug March 20th, 2017

Block copolymer micellization as a protection strategy for DNA origami March 17th, 2017

Nanocages for gold particles: what is happening inside? March 16th, 2017

Discoveries

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Promising results obtained with a new electrocatalyst that reduces the need for platinum: Researchers from Aalto University have succeeded in manufacturing electrocatalysts used for storing electric energy with one-hundredth of the amount of platinum that is usually needed March 24th, 2017

Rice U. refines filters for greener natural gas: New study defines best materials for carbon capture, methane selectivity March 23rd, 2017

Artificial photosynthesis steps into the light: Rice University lab turns transition metals into practical catalyst for solar, other applications March 23rd, 2017

Materials/Metamaterials

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Promising results obtained with a new electrocatalyst that reduces the need for platinum: Researchers from Aalto University have succeeded in manufacturing electrocatalysts used for storing electric energy with one-hundredth of the amount of platinum that is usually needed March 24th, 2017

Rice U. refines filters for greener natural gas: New study defines best materials for carbon capture, methane selectivity March 23rd, 2017

Artificial photosynthesis steps into the light: Rice University lab turns transition metals into practical catalyst for solar, other applications March 23rd, 2017

Announcements

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Promising results obtained with a new electrocatalyst that reduces the need for platinum: Researchers from Aalto University have succeeded in manufacturing electrocatalysts used for storing electric energy with one-hundredth of the amount of platinum that is usually needed March 24th, 2017

Rice U. refines filters for greener natural gas: New study defines best materials for carbon capture, methane selectivity March 23rd, 2017

Artificial photosynthesis steps into the light: Rice University lab turns transition metals into practical catalyst for solar, other applications March 23rd, 2017

Aerospace/Space

Space energy technology restored to make power stations more efficient: Scientists use graphene to reinvent abandoned heat energy converter technology March 7th, 2017

Applied Graphene Materials plc - Significant commercial progress in AGM’s three core sectors March 3rd, 2017

Triboelectric Nanogenerators Boost Mass Spectrometry Performance March 1st, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

Nanobiotechnology

Nanobiotix: The Independent Data Monitoring Committee Recommends the Continuation of the Ongoing Phase II/III Trial of NBTXR3 in Soft Tissue Sarcoma March 23rd, 2017

Nanoparticle paves the way for new triple negative breast cancer drug March 20th, 2017

Block copolymer micellization as a protection strategy for DNA origami March 17th, 2017

Nanocages for gold particles: what is happening inside? March 16th, 2017

Research partnerships

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Rice U. refines filters for greener natural gas: New study defines best materials for carbon capture, methane selectivity March 23rd, 2017

Artificial photosynthesis steps into the light: Rice University lab turns transition metals into practical catalyst for solar, other applications March 23rd, 2017

Pulverizing e-waste is green, clean -- and cold: Rice, Indian Institute researchers use cryo-mill to turn circuit boards into separated powders March 21st, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project