Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Magnetic Nanoparticles Could Be Used To Track How Neural Cells Heal Spinal Injuries

Stem cells attached to biocompatible nanoparticles can be visualised by MRI after transplantation into spinal cord slices.
Stem cells attached to biocompatible nanoparticles can be visualised by MRI after transplantation into spinal cord slices.

Abstract:
Neural stem cells are a promising treatment for repairing spinal cord injuries as they have the ability to generate tissue, but there is no effective way of monitoring the cells for long periods of time after transplantation.

Magnetic Nanoparticles Could Be Used To Track How Neural Cells Heal Spinal Injuries

London, UK | Posted on February 24th, 2011

Nguyen TK Thanh at the Davy Faraday Research Laboratory, University College London, LCN and the Royal Institution, and colleagues, believe they have the answer. They have developed hollow biocompatible cobalt-platinum nanoparticles and attached them to the stem cells. The nanoparticles are stable for months and have a high magnetic moment - tendency to align with a magnetic field - so that low concentrations can be detected using magnetic resonance imaging (MRI).

'Magnetic nanoparticles are emerging as novel contrast and tracking agents in medical imaging,' says Samir Pal at the California Institute of Technology, US, an expert in biological-nanoparticle interactions. 'When used as a contrast agent for MRI, the nanoparticles allow researchers and clinicians to enhance the tissue contrast of an area of interest by increasing the relaxation rate of water.'

The team labelled stem cells with their nanoparticles, injected them into spinal cord slices and took images of their progress over time. They found that low numbers of the nanoparticle-loaded stem cells could still be detected two weeks after transplantation. 'The new method demonstrates the feasibility of reliable, noninvasive MRI imaging of nanoparticle-labelled cells,' says Thanh.

Thanh hopes that her stem cell tracking method will be used during stem cell replacement therapy for many central nervous system diseases. Her team is working towards developing nanoparticles that can be used to diagnose and treat these diseases.

Harriet Brewerton

####

About London Centre for Nanotechnology
The London Centre for Nanotechnology is a UK-based multidisciplinary enterprise operating at the forefront of science and technology. Our purpose is to solve global problems in information processing, healthcare, energy and environment through the application of nanoscience and nanotechnology. Founded in 2003, the LCN is a joint venture between University College London and Imperial College London and based at the Bloomsbury and South Kensington sites.

For more information, please click here

Contacts:
London Centre for Nanotechnology
17-19 Gordon Street
London WC1H 0AH
tel: +44 (0)20 7679 0604
fax: +44 (0)20 7679 0595
email:

Copyright © London Centre for Nanotechnology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection

Related News Press

News and information

Nanofiltration Membrane Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Nanozirconia Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Self-Healing Nano Anti-rust Coatings Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Nano Spray Instrument Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Imaging

Take a trip through the brain July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

Reshaping the solar spectrum to turn light to electricity: UC Riverside researchers find a way to use the infrared region of the sun's spectrum to make solar cells more efficient July 27th, 2015

Nanomedicine

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015

Take a trip through the brain July 30th, 2015

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Announcements

Nano Spray Instrument Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Nanocellulose Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Theoretical Physicists at Freie Universitšt Berlin Develop New Insights into Interface between Classical and Quantum Worlds July 31st, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project