Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Magnetic Nanoparticles Could Be Used To Track How Neural Cells Heal Spinal Injuries

Stem cells attached to biocompatible nanoparticles can be visualised by MRI after transplantation into spinal cord slices.
Stem cells attached to biocompatible nanoparticles can be visualised by MRI after transplantation into spinal cord slices.

Abstract:
Neural stem cells are a promising treatment for repairing spinal cord injuries as they have the ability to generate tissue, but there is no effective way of monitoring the cells for long periods of time after transplantation.

Magnetic Nanoparticles Could Be Used To Track How Neural Cells Heal Spinal Injuries

London, UK | Posted on February 24th, 2011

Nguyen TK Thanh at the Davy Faraday Research Laboratory, University College London, LCN and the Royal Institution, and colleagues, believe they have the answer. They have developed hollow biocompatible cobalt-platinum nanoparticles and attached them to the stem cells. The nanoparticles are stable for months and have a high magnetic moment - tendency to align with a magnetic field - so that low concentrations can be detected using magnetic resonance imaging (MRI).

'Magnetic nanoparticles are emerging as novel contrast and tracking agents in medical imaging,' says Samir Pal at the California Institute of Technology, US, an expert in biological-nanoparticle interactions. 'When used as a contrast agent for MRI, the nanoparticles allow researchers and clinicians to enhance the tissue contrast of an area of interest by increasing the relaxation rate of water.'

The team labelled stem cells with their nanoparticles, injected them into spinal cord slices and took images of their progress over time. They found that low numbers of the nanoparticle-loaded stem cells could still be detected two weeks after transplantation. 'The new method demonstrates the feasibility of reliable, noninvasive MRI imaging of nanoparticle-labelled cells,' says Thanh.

Thanh hopes that her stem cell tracking method will be used during stem cell replacement therapy for many central nervous system diseases. Her team is working towards developing nanoparticles that can be used to diagnose and treat these diseases.

Harriet Brewerton

####

About London Centre for Nanotechnology
The London Centre for Nanotechnology is a UK-based multidisciplinary enterprise operating at the forefront of science and technology. Our purpose is to solve global problems in information processing, healthcare, energy and environment through the application of nanoscience and nanotechnology. Founded in 2003, the LCN is a joint venture between University College London and Imperial College London and based at the Bloomsbury and South Kensington sites.

For more information, please click here

Contacts:
London Centre for Nanotechnology
17-19 Gordon Street
London WC1H 0AH
tel: +44 (0)20 7679 0604
fax: +44 (0)20 7679 0595
email:

Copyright © London Centre for Nanotechnology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection

Related News Press

News and information

New Hopes for Treatment of Intestine Cancer by Edible Nanodrug March 2nd, 2015

Imec, Holst Centre and Renesas Present Worldís Lowest Power 2.4GHz Radio Chip for Bluetooth Low Energy March 1st, 2015

Imec, Murata, and Huawei Introduce Breakthrough Solution for TX-to-RX Isolation in Reconfigurable, Multiband Front-End Modules for Mobile Phones: Electrical-Balance Duplexers Pave the Way to Integrated Solution for TX-to-RX Isolation March 1st, 2015

Imec Demonstrates Compact Wavelength-Division Multiplexing CMOS Silicon Photonics Transceiver March 1st, 2015

Imaging

Renishaw and Bruker team up for a workshop on TERS and co-localised AFM Raman February 26th, 2015

Real-time observation of bond formation by using femtosecond X-ray liquidography February 26th, 2015

Bruker-Sponsored Sixth AFM BioMed Conference Highlights Increasing Impact of AFM in Biological Applications February 26th, 2015

Dendrite eraser: New electrolyte rids batteries of short-circuiting fibers: Solution enables a battery with both high efficiency & current density February 24th, 2015

Nanomedicine

New Hopes for Treatment of Intestine Cancer by Edible Nanodrug March 2nd, 2015

Graphene Shows Promise In Eradication Of Stem Cancer Cells March 1st, 2015

Novel Method to Determine Optical Purity of Drug Components March 1st, 2015

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Announcements

New Hopes for Treatment of Intestine Cancer by Edible Nanodrug March 2nd, 2015

Imec Demonstrates Compact Wavelength-Division Multiplexing CMOS Silicon Photonics Transceiver March 1st, 2015

onic Present breakthrough in CMOS-based Transceivers for mm-Wave Radar Systems March 1st, 2015

Graphene Shows Promise In Eradication Of Stem Cancer Cells March 1st, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE