Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Magnetic Field Directs Nanoparticles to Tumors

Abstract:
To improve the tumor-specific delivery of drug to tumors, a team of investigators from the University of California, San Diego (UCSD) has created a system of nanoparticles-within-a-nanoparticle that can be directed to and concentrated at the site of tumor using a magnetic field. Once at the tumor site, radiofrequency irradiation triggers drug release from the nanoparticles, bathing the tumors in drug and markedly reducing the growth of the tumors.

Magnetic Field Directs Nanoparticles to Tumors

Bethesda, MD | Posted on November 30th, 2010

Reporting its work in the journal Nano Letters, a research team led by Sungho Jin described the multiple steps it uses to create these multi-component nanoparticles that contain both magnetic nanoparticles and the drug Camptothecin trapped within a silica shell. Trapped within the silica nanoparticle, the close proximity of the hundreds of magnetic iron oxide nanoparticles boosts their responsiveness to a magnetic field applied from outside the body. More importantly, at moderate magnetic field strengths the nanoparticles not only accumulate in the vicinity of a tumor but also penetrate into the tumor mass.

Based on these initial results, the investigators injected the nanoparticles into mice implanted with human breast tumors. After using a magnetic field to direct the nanoparticles to tumors during a two-hour period, the researchers subjected the animals to three 8-minute exposures to radiofrequency irradiation. The treated animals experienced a marked reduction in the size of their tumors and experienced no noticeable side effects.

####

About The National Cancer Institute (NCI)
The NCI Alliance for Nanotechnology in Cancer is engaged in efforts to harness the power of nanotechnology to radically change the way we diagnose, treat and prevent cancer.

The NCI Alliance for Nanotechnology in Cancer is a comprehensive, systematized initiative encompassing the public and private sectors, designed to accelerate the application of the best capabilities of nanotechnology to cancer.

Currently, scientists are limited in their ability to turn promising molecular discoveries into benefits for cancer patients. Nanotechnology can provide the technical power and tools that will enable those developing new diagnostics, therapeutics, and preventives to keep pace with today’s explosion in knowledge.

For more information, please click here

Contacts:
National Cancer Institute
Center for Strategic Scientific Initiatives
ATTN: NCI Office of Cancer Nanotechnology Research (OCNR)
Building 31, Room 10A52
31 Center Drive, MSC 2580
Bethesda, MD 20892-2580
(301) 451-8983

Copyright © The National Cancer Institute (NCI)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

View abstract - "Magnetically Vectored Nanocapsules for Tumor-Penetration and Remotely Switchable On-Demand Drug Release."

Related News Press

News and information

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Imaging

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Govt.-Legislation/Regulation/Funding/Policy

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

Rutgers, NIST physicists report technology with potential for sub-micron optical switches March 31st, 2015

SUNY Poly CNSE and Title Sponsor SEFCU Name Capital Region Teams Advancing to the Final Round of the 2015 New York Business Plan Competition March 30th, 2015

Princess Margaret scientists convert microbubbles to nanoparticles: Harnessing light to advance tumor imaging, provide platform for targeted treatment March 30th, 2015

Nanomedicine

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Nanion Technologies Appoints James Costantin as Director of Customer Relations: Nanion is pleased to announce the appointment of Dr. James Costantin as Director of Customer Relations at Nanion Technologies Inc. March 31st, 2015

Nanomedicine shines light on combined force of nanomedicine and regenerative medicine March 31st, 2015

Prototype 'nanoneedles' generate new blood vessels in mice: Scientists have developed tiny 'nanoneedles' that have successfully prompted parts of the body to generate new blood vessels, in a trial in mice March 31st, 2015

Discoveries

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Light-powered gyroscope is world's smallest: Promises a powerful spin on navigation April 1st, 2015

Announcements

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE