Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Detecting cancer with the prick of a finger

Chemistry professor Adam Woolley created a microchip that could speed up cancer detection.  Photograph by Mark A. Philbrick
Chemistry professor Adam Woolley created a microchip that could speed up cancer detection. Photograph by Mark A. Philbrick

Abstract:
BYU researchers create microdevice to speed up cancer detection

By Todd Hollingshead

Detecting cancer with the prick of a finger

Provo, UT | Posted on November 20th, 2010

Researchers at BYU have created a micro device that could both decrease the amount of blood and time needed to test for cancer-markers in a patient's blood.

Chemistry professor Adam Woolley's research, published in a recent issue of the journal, Lab on a Chip, details the device and technique that would allow for effective detection of biomarkers in a blood sample in a matter of minutes rather than days or weeks.

"You could walk into the doctor's office, the nurse could prick your finger instead of sticking a needle in your vein, and 30 or 40 minutes later, you'd get the results back in the same doctor's office," Woolley said.

Woolley said the current approach for detecting biomarkers, ELISA (enzyme-linked immunosorbent assay), works well as long as you're doing it in high volumes. This is why blood samples are usually sent to a clinical lab where they can run dozens of samples at the same time.

And while ELISA is efficient and cost effective if, say, there are 90 blood samples to process, the BYU micro device would allow a technician to look at just one sample quickly and cost-effectively to determine if there are markers for, say, breast cancer or prostate cancer.

The microchip researched and created by Woolley and doctoral student Weichun Yang could lead to effective testing for cancer-marking proteins with the use of only microliters of blood instead of milliliters - a smaller sample by a factor of a thousand.

"Detecting cancer biomarkers in a point-of-care setting can significantly improve the throughput of cancer screening and diagnose a cancer tumor at its early stage," said Yang, lead author on the paper. "These devices provide a robust, quick, and portable system for early stage disease diagnosis."

Whereas ELISA uses a series of antibodies as hooks to grab targeted proteins and identify them, Woolley's method uses only one antibody step, which is then followed by a step where voltage is applied and the proteins are identified by the speed at which they move.

The new micro device can also detect multiple cancer biomarkers in blood simultaneously. In this particular round of research, Woolley and his team used the chip to detect four biomarkers simultaneously, but the device has the potential to detect upwards of 10 or 20.

Woolley said he and his team are now looking at ways to speed up the biomarker detection process even more. Ideally, he'd like to get the 30- to 40-minute process down to 20, 15 or even 10 minutes.

"If you learn from your doctor that you might have a life-threatening disease and that some initial testing must be performed, you don't want to wait weeks to find out what's going on," Woolley said. "You'd like to know that very day."

Woolley's research was funded by a National Institutes of Health grant awarded in 2006. Other co-authors on the study were post-doctorates Ming Yu and Xiuhua Sun.

####

For more information, please click here

Contacts:
Media Contact
Todd Hollingshead
801-422-8373

Copyright © Brigham Young University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Report highlights opportunities and risks associated with synthetic biology and bioengineering November 22nd, 2017

Quantum optics allows us to abandon expensive lasers in spectroscopy: Lomonosov Moscow State University scientists have invented a new method of spectroscopy November 21st, 2017

Nano-watch has steady hands November 21st, 2017

Nano Global, Arm Collaborate on Artificial Intelligence Chip to Drive Health Revolution by Capturing and Analyzing Molecular Data in Real Time November 21st, 2017

Microfluidics/Nanofluidics

Using light to propel water : With new method, MIT engineers can control and separate fluids on a surface using only visible light April 25th, 2017

Nano-SPEARs gently measure electrical signals in small animals: Rice University's tiny needles simplify data gathering to probe diseases, test drugs April 17th, 2017

Particle Works creates range of high performance quantum dots February 23rd, 2017

DNA 'barcoding' allows rapid testing of nanoparticles for therapeutic delivery February 7th, 2017

Govt.-Legislation/Regulation/Funding/Policy

EC Project Aims at Creating and Commercializing Cyber-Physical-System Solutions November 14th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3ís significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Leti Joins DARPA-Funded Project to Develop Implantable Device for Restoring Vision November 9th, 2017

Nanoshells could deliver more chemo with fewer side effects: In vitro study verifies method for remotely triggering release of cancer drugs November 8th, 2017

Possible Futures

Report highlights opportunities and risks associated with synthetic biology and bioengineering November 22nd, 2017

Quantum optics allows us to abandon expensive lasers in spectroscopy: Lomonosov Moscow State University scientists have invented a new method of spectroscopy November 21st, 2017

Nano-watch has steady hands November 21st, 2017

Nano Global, Arm Collaborate on Artificial Intelligence Chip to Drive Health Revolution by Capturing and Analyzing Molecular Data in Real Time November 21st, 2017

Academic/Education

LuleŚ University of Technology is using the Deben CT5000TEC stage to perform x-ray microtomography experiments with the ZEISS Xradia 510 Versa to understand deformation and strain inside inhomogeneous materials November 7th, 2017

Park Systems Announces the Grand Opening of the Park NanoScience Center at SUNY Polytechnic Institute November 3rd, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Nanomedicine

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3ís significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Arrowhead to Present at 29th Annual Piper Jaffray Healthcare Conference November 14th, 2017

A new way to mix oil and water: Condensation-based method developed at MIT could create stable nanoscale emulsions November 8th, 2017

Announcements

Report highlights opportunities and risks associated with synthetic biology and bioengineering November 22nd, 2017

Quantum optics allows us to abandon expensive lasers in spectroscopy: Lomonosov Moscow State University scientists have invented a new method of spectroscopy November 21st, 2017

Nano-watch has steady hands November 21st, 2017

Nano Global, Arm Collaborate on Artificial Intelligence Chip to Drive Health Revolution by Capturing and Analyzing Molecular Data in Real Time November 21st, 2017

Nanobiotechnology

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3ís significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Arrowhead to Present at 29th Annual Piper Jaffray Healthcare Conference November 14th, 2017

Nanoshells could deliver more chemo with fewer side effects: In vitro study verifies method for remotely triggering release of cancer drugs November 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project