Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nanobiotechnology experts join forces to improve TB testing

Abstract:
NPL and Orla Protein Technologies have been awarded 91,000 by the Technology Strategy Board to investigate improved methods for the detection of tuberculosis (TB).

Nanobiotechnology experts join forces to improve TB testing

UK | Posted on October 20th, 2010

The two companies have been awarded joint funding for a research project that could see significant advances in the quest to aid detection and eradication of TB, across the world.

The project, which has just begun, involves a combination of cutting edge technologies and expertise, including areas of molecular and biological diagnostics (Orla), and measurement science and infectious diseases (NPL).

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of almost all cases if tuberculosis. More than 5,000 people die every day from TB, largely in the developing world. TB is one of the major lethal factors among AIDS patients. Largely, TB affects the developing world where the situation is worsened with the infection becoming one of the main lethal factors among HIV-infected individuals.

Current methods of TB detection suffer from a need for large sample volumes, long preparation times and different results from different patient groups. This has led to a demand for more sensitive and rapid approaches to be developed.

The Consortium aims to meet this demand, by producing systems which dramatically advance current methods; helping to improve the sensitivity, specificity, cost and speed of results.

Max Ryadnov, Project Leader at NPL, said: "The main objective of the project is to demonstrate the possibility of detecting MTB quickly and cost effectively in both clinical and near-patient settings. Such capability is a 'holy grail' of modern diagnostics of MTB and would significantly impact on the UK and global healthcare markets."

The study will make use of techniques developed at NPL for the detection of biomarkers - proteins which indicate disease - to rapidly assess the presence of the MTB protein in a sample. These techniques are empowered by oriented immobilisation of proteins developed by Orla, which allows us to easily create a single patterned layer of proteins for analysis. This makes the manufacture and use of biomarker detection dramatically simpler.

Dale Athey, Chief Executive at Orla, said: "The development of such procedures will help to substantially improve health systems in resource-limiting settings, particularly in HIV-infected TB cases, where sensitivity remains well below confidence limits for all MTB tests. We hope the project will allow us to significantly improve consistency and enhanced sensitivity for cost-effective, easy to use point-of-care-solutions for the detection and eradication of MTB."

The project team will also work with colleagues in the Health Protection Agency for advice on microbiology, and to arrange testing in a clinical environment.

####

For more information, please click here

Copyright © National Physical Laboratory

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Searching for errors in the quantum world September 21st, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

Nanomedicine

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

NUS researchers invent new test kit for quick, accurate and low-cost screening of diseases: Test results are denoted by a color change and could be further analyzed by a smartphone app, making it attractive as a point-of-care diagnostic device September 19th, 2018

Announcements

Searching for errors in the quantum world September 21st, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Halas wins American Chemical Society Award in Colloid Chemistry: Rice University nanophotonics pioneer honored for colloid research September 18th, 2018

New photonic chip promises more robust quantum computers September 14th, 2018

A Comprehensive Guide: The Future of Nanotechnology September 13th, 2018

Nanobiotechnology

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

NUS researchers invent new test kit for quick, accurate and low-cost screening of diseases: Test results are denoted by a color change and could be further analyzed by a smartphone app, making it attractive as a point-of-care diagnostic device September 19th, 2018

Researchers develop microbubble scrubber to destroy dangerous biofilms September 19th, 2018

Research partnerships

Leti Announces EU Project to Develop Powerful, Inexpensive Sensors with Photonic Integrated Circuits: REDFINCH Members Initially Targeting Applications for Gas Detection and Analysis For Refineries & Petrochemical Industry and Protein Analysis for Dairy Industry September 19th, 2018

Researchers develop microbubble scrubber to destroy dangerous biofilms September 19th, 2018

Leti & EFI Aim to Dramatically Improve Reliability & Speed of Low-Cost Electronic Devices for Autos: Project Will Extend Model Predictive Control Technique to Microcontrollers, Digital Signal Processors and Other Devices that Lack Powerful Computation Capabilities September 18th, 2018

Tiny camera lens may help link quantum computers to network September 14th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project