Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanobiotechnology experts join forces to improve TB testing

Abstract:
NPL and Orla Protein Technologies have been awarded £91,000 by the Technology Strategy Board to investigate improved methods for the detection of tuberculosis (TB).

Nanobiotechnology experts join forces to improve TB testing

UK | Posted on October 20th, 2010

The two companies have been awarded joint funding for a research project that could see significant advances in the quest to aid detection and eradication of TB, across the world.

The project, which has just begun, involves a combination of cutting edge technologies and expertise, including areas of molecular and biological diagnostics (Orla), and measurement science and infectious diseases (NPL).

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of almost all cases if tuberculosis. More than 5,000 people die every day from TB, largely in the developing world. TB is one of the major lethal factors among AIDS patients. Largely, TB affects the developing world where the situation is worsened with the infection becoming one of the main lethal factors among HIV-infected individuals.

Current methods of TB detection suffer from a need for large sample volumes, long preparation times and different results from different patient groups. This has led to a demand for more sensitive and rapid approaches to be developed.

The Consortium aims to meet this demand, by producing systems which dramatically advance current methods; helping to improve the sensitivity, specificity, cost and speed of results.

Max Ryadnov, Project Leader at NPL, said: "The main objective of the project is to demonstrate the possibility of detecting MTB quickly and cost effectively in both clinical and near-patient settings. Such capability is a 'holy grail' of modern diagnostics of MTB and would significantly impact on the UK and global healthcare markets."

The study will make use of techniques developed at NPL for the detection of biomarkers - proteins which indicate disease - to rapidly assess the presence of the MTB protein in a sample. These techniques are empowered by oriented immobilisation of proteins developed by Orla, which allows us to easily create a single patterned layer of proteins for analysis. This makes the manufacture and use of biomarker detection dramatically simpler.

Dale Athey, Chief Executive at Orla, said: "The development of such procedures will help to substantially improve health systems in resource-limiting settings, particularly in HIV-infected TB cases, where sensitivity remains well below confidence limits for all MTB tests. We hope the project will allow us to significantly improve consistency and enhanced sensitivity for cost-effective, easy to use point-of-care-solutions for the detection and eradication of MTB."

The project team will also work with colleagues in the Health Protection Agency for advice on microbiology, and to arrange testing in a clinical environment.

####

For more information, please click here

Copyright © National Physical Laboratory

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Future solar panels September 2nd, 2014

Nano-forests to reveal secrets of cells September 2nd, 2014

Nanomedicine

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Nano-forests to reveal secrets of cells September 2nd, 2014

Nanoscale assembly line August 29th, 2014

Copper shines as flexible conductor August 29th, 2014

Announcements

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Future solar panels September 2nd, 2014

Nano-forests to reveal secrets of cells September 2nd, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Rice physicist emerges as leader in quantum materials research: Nevidomskyy wins both NSF CAREER Award and Cottrell Scholar Award August 20th, 2014

Oxford Instruments Asylum Research Receives the 2014 Microscopy Today Innovation Award for blueDrive Photothermal Excitation August 18th, 2014

AQUANOVA receives Technology Leadership Award 2014 FROST & SULLIVAN honors NovaSOL® Technology again August 12th, 2014

Focal blood-brain-barrier disruption with high-frequency pulsed electric fields August 12th, 2014

Nanobiotechnology

Nano-forests to reveal secrets of cells September 2nd, 2014

Nanoscale assembly line August 29th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Сalculations with Nanoscale Smart Particles August 19th, 2014

Research partnerships

Leading European communications companies and research organizations have launched an EU project developing the future 5th Generation cellular mobile networks August 28th, 2014

New technique uses fraction of measurements to efficiently find quantum wave functions August 28th, 2014

The thunder god vine, assisted by nanotechnology, could shake up future cancer treatment: Targeted therapy for hepatocellular carcinoma using nanotechnology August 27th, 2014

Competition for Graphene: Berkeley Lab Researchers Demonstrate Ultrafast Charge Transfer in New Family of 2D Semiconductors August 26th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE