Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Arrowhead Portfolio Company, Nanotope, Inc. Enters Agreement with Smith & Nephew for the License and Development of Cartilage Regeneration Technology

Abstract:
Arrowhead Research Corporation (NASDAQ: ARWR) today announced that its portfolio company, Nanotope, Inc., has entered into an agreement with Smith & Nephew, Inc., a member of the Smith & Nephew plc group (LSE: SN; NYSE: SNN) to develop a cartilage regeneration product for human healthcare markets using a subset of its proprietary regenerative medicine technology.

Arrowhead Portfolio Company, Nanotope, Inc. Enters Agreement with Smith & Nephew for the License and Development of Cartilage Regeneration Technology

Pasadena, CA | Posted on October 18th, 2010

Under the agreement, Nanotope and Smith & Nephew will work together to optimize a cartilage regeneration product based on Nanotope's proprietary platform. Smith & Nephew will conduct and assume costs associated with preclinical tests required to support clinical trials, purchase preclinical material from Nanotope, and assume all clinical trial costs. Nanotope will potentially receive up to $26.55 million in milestone payments plus sales royalties if all milestones are met.

This represents Nanotope's first commercial transaction and is in line with its strategy to leverage larger companies' development and distribution capabilities within individual target markets. Nanotope's broad proprietary platform is flexible and may be customized to support the regeneration of many diverse tissues. As such, it could lead to the development of a large number of therapeutics. Nanotope's model is to establish many highly focused partnerships incorporating portions of its technology for use in specific indications or tissue types. This is intended to maximize the number of product candidates entering the clinic, increase speed to market, and deploy Nanotope resources efficiently. As a global leader in orthopedics and sports medicine, Smith & Nephew is well positioned to help bring an advanced cartilage repair product to market to provide effective treatment to a condition with large economic and quality of life costs.

"Smith & Nephew is ideal for the commercialization of Nanotope's cartilage repair technology given its global reach in orthopedics and potential synergies of a new cartilage regeneration capability with its suite of existing orthopedic products," said Dr. Christopher Anzalone, Arrowhead's President and Chief Executive Officer. "Smith & Nephew has a solid track record of bringing innovative new products to market, and we view this agreement as a validation of Nantope's technology and business strategy. This deal also represents the achievement of a key milestone Arrowhead has articulated for the last quarter of calendar 2010."

Mark Augusti, President of Smith & Nephew's Biologics and Spine Business unit, commented on the agreement: "We are always searching for alliances with businesses whose technologies address the major unmet needs of our market. Cartilage repair is a clear area of interest to us and we are very pleased to be partnering with Nanotope in this area."

Nanotope's technological platform was first developed at Northwestern University by Dr. Samuel I. Stupp, Professor of Materials Science & Engineering, Chemistry and Medicine and Director of the Institute for BioNanotechnology in Medicine (IBNAM). Nanotope continues to develop a suite of products, each customized to regenerate specific tissues; including neuronal, vascular, bone, and myocardial. The product candidates, as well as that which is subject to the Smith & Nephew agreement, are injectable compounds that work with surviving cells in and around the point of damage to initiate and support tissue regeneration and growth. Nanotope's other lead products include neuron regeneration for prevention or reversal of paralysis associated with spinal cord injury, advanced wound healing, and the treatment of peripheral artery disease. Nanotope intends to pursue additional partnerships in these and other indications.

Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995:

This news release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These statements are based upon our current expectations and speak only as of the date hereof. Our actual results may differ materially and adversely from those expressed in any forward-looking statements as a result of various factors and uncertainties, including the current state of the economy, capital resources available to us, the future success of our scientific studies, our ability to successfully develop products, rapid technological change in our markets, changes in demand for our future products, legislative, regulatory and competitive developments and general economic conditions. Our most recent Annual Report on Form 10-K, as amended, and subsequent Quarterly Reports on Form 10-Q and other SEC filings discuss some of the important risk factors that may affect our business, results of operations and financial condition, including the risks relating to the development of new drug candidates. We disclaim any intent to revise or update publicly any forward-looking statements for any reason.

####

About Arrowhead Research Corporation
Arrowhead Research Corporation (NASDAQ: ARWR) is a nanotechnology company commercializing new technologies in the areas of life sciences, electronics, and energy. Arrowhead is seeking to build value for shareholders through the progress of majority owned subsidiaries. Currently, Arrowhead has four subsidiaries commercializing nanotech products and applications and minority investments in two privately held nanobiotech companies.

About Smith & Nephew
Smith & Nephew is a global medical technology company with leadership positions in Orthopedics; including Reconstruction, Trauma and Clinical Therapies; Endoscopy; including Sports Medicine; and Advanced Wound Management. Smith & Nephew is a global leader in arthroscopy and advanced wound management and is one of the leading global orthopedics companies. The Company has distribution channels, purchasing agents and buying entities in over 90 countries worldwide. Annual sales in 2009 were nearly $3.8 billion.

For more information, please click here

Contacts:
Investor Relations:
The Piacente Group, Inc.
Brandi Floberg
212-481-2050

Copyright © Arrowhead Research Corporation

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Physicists solve quantum tunneling mystery: ANU media release: An international team of scientists studying ultrafast physics have solved a mystery of quantum mechanics, and found that quantum tunneling is an instantaneous process May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Who needs water to assemble DNA? Non-aqueous solvent supports DNA nanotechnology May 27th, 2015

Controlled Release of Anticorrosive Materials in Spot by Nanocarriers May 27th, 2015

Nanomedicine

New electronic stent could provide feedback and therapy then dissolve May 27th, 2015

Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Announcements

Physicists solve quantum tunneling mystery: ANU media release: An international team of scientists studying ultrafast physics have solved a mystery of quantum mechanics, and found that quantum tunneling is an instantaneous process May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Who needs water to assemble DNA? Non-aqueous solvent supports DNA nanotechnology May 27th, 2015

Controlled Release of Anticorrosive Materials in Spot by Nanocarriers May 27th, 2015

Nanobiotechnology

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Who needs water to assemble DNA? Non-aqueous solvent supports DNA nanotechnology May 27th, 2015

DNA Double Helix Does Double Duty in Assembling Arrays of Nanoparticles: Synthetic pieces of biological molecule form framework and glue for making nanoparticle clusters and arrays May 25th, 2015

Alliances/Partnerships/Distributorships

Samtec, Global Provider of Interconnect Systems, Joins IRT Nanoelec Silicon Photonics Program May 21st, 2015

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

Industrial Nanotech, Inc. Announces Official Launch of the Eagle Platinum Tile May 19th, 2015

DiATOME enables surface preparation for AFM and FIB May 19th, 2015

New-Contracts/Sales/Customers

Argonne chooses Beneqs TFS 500 Atomic Layer Deposition System: Modularity and flexibility make for a natural choice May 14th, 2015

New JEOL E-Beam Lithography System to Enhance Quantum NanoFab Capabilities May 6th, 2015

FEI Partners With the George Washington University to Equip New Science & Engineering Hall: Suite of new high-performance microscopes will be used for cutting-edge experiments at GWs new research facility April 29th, 2015

Renishaw Raman systems used to study 2D materials at Boston University, Massachusetts, USA. April 28th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project