Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > 'Molecular Rollar Coaster' distinguishes between molecules

The 'molecular roller coaster' of two molecules (illustration: Florian Sterl)
The 'molecular roller coaster' of two molecules (illustration: Florian Sterl)

Abstract:
Research that made it to the cover of the authoritative scientific journal Analytical Chemistry this week has shown that the detection method developed by researchers at the University of Twente's research institutes MESA+ and MIRA is even more sensitive than demonstrated earlier. Not only can it detect molecules accurately, it also shows the difference between them very clearly. The research was co-financed by Nanoned (a national nanotechnology R&D initiative that combines the Dutch strengths in nanoscience and technology in a national network), the Foundation for Fundamental Research on Matter (FOM) and the Netherlands Organization for Scientific Research (NWO).

'Molecular Rollar Coaster' distinguishes between molecules

The Netherlands | Posted on September 15th, 2010

The molecules in a solution can be measured with a technology known as Coherent Anti-Stokes Raman Spectroscopy (CARS). Molecules that are very similar are, however, difficult to distinguish from one another. University of Twente (UT) researchers had, at an earlier stage, already introduced an improved form of CARS, which is much more sensitive and with which molecules can be tracked down in a very much lower concentration. In the study now published, they show that their method is not only much more sensitive, but that it also enables them to detect up to ten different sorts of molecules simultaneously. In the past, several successive measurements had to be carried out to achieve this, so work of this kind can now be carried out considerably faster. This technology also makes it possible for researchers to 'film' how medicines are released from a tablet or how a living cell burns fats. The researchers envisage applications in the pharmaceutical industry and cell biology research for this technology.

Molecular roller coaster

If you shine laser light on molecules, some of these molecules will absorb photons (light particles) and emit new photons. The emitted photons then have a higher energy level than the original photons. With the aid of Anti-Stokes Raman Spectroscopy, these photons can be caught and used to determine which molecules are present in the solution. The method looks at the amplitude of the vibrations of the light. The UT researchers' new method looks not only at the amplitude of the vibration, but also at the phase. Plotting the amplitude and the phase of the vibration of the light in a graph creates a complicated spiral dubbed the 'molecular roller coaster' by the researchers. As a result of this roller coaster, similar substances can easily be distinguished from one another.

This research was carried out by the research groups Optical Sciences (MESA+ Institute for Nanotechnology) and Medical Cell BioPhysics (MIRA) and was co-financed by Nanoned, FOM and NWO. For more information or a digital version of the article 'Visualizing Resonances in the Complex Plane with Vibrational Phase Contrast Coherent Anti-Stokes Raman Scattering' by Martin Jurna, Erik Garbacik, Jeroen Korterik, Jennifer Herek, Cees Otto and Herman Offerhaus, please contact the research information officer Joost Bruysters on +31 (0)53 489 2773 / +31 (0)6 1048 8228.

####

For more information, please click here

Contacts:
Joost Bruysters
+31 (0)53 489 2773
+31 (0)6 1048 8228

Copyright © University of Twente

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Possible Futures

UCLA chemists synthesize narrow ribbons of graphene using only light and heat: Tiny structures could be next-generation solution for smaller electronic devices December 8th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Creating a new kind of metallic glass December 7th, 2017

Academic/Education

Luleå University of Technology is using the Deben CT5000TEC stage to perform x-ray microtomography experiments with the ZEISS Xradia 510 Versa to understand deformation and strain inside inhomogeneous materials November 7th, 2017

Park Systems Announces the Grand Opening of the Park NanoScience Center at SUNY Polytechnic Institute November 3rd, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Nanomedicine

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Arrowhead Presents New Clinical Data Demonstrating a Sustained Host Response in Hepatitis B Patients Following RNAi Therapy — Up to 5.0 log10 reduction in HBsAg observed; data presented at HEP DART 2017 — December 6th, 2017

Copper will replace toxic palladium and expensive platinum in the synthesis of medications: The effectiveness of copper nanoparticles as a catalyst has been proven December 5th, 2017

Announcements

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Tools

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

JPK Instruments announce partnership with Swiss company, Cytosurge AG. The partnership makes Cytosurge’s FluidFM® technology available on the JPK NanoWizard® AFM platform December 8th, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

Deben reports on a new publication from scientists at La Trobe University in Australia where their CT500 stage is used in micro scanning tomography experiments to better understand ceramic matrix composites under load November 29th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project