Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Revolutionary medical dressing uses nano-technology to fight infection

The dressing will be coated with nanocapsules that contain antibiotics and a dye (shown in red) that are broken open by toxins (green) produced by disease-causing bacteria (yellow)
The dressing will be coated with nanocapsules that contain antibiotics and a dye (shown in red) that are broken open by toxins (green) produced by disease-causing bacteria (yellow)

Abstract:
Researchers are using nanotechnology to develop a medical dressing which will detect and treat infection in wounds.

Revolutionary medical dressing uses nano-technology to fight infection

Bath | Posted on July 26th, 2010

Scientists at the University of Bath and the burns team at the Southwest UK Paediatric Burns Centre at Frenchay Hospital in Bristol are working together with teams across Europe and Australia to create an advanced wound dressing.

The dressing will work by releasing antibiotics from nanocapsules triggered by the presence of disease-causing pathogenic bacteria, which will target treatment before the infection takes hold.

The dressing will also change colour when the antibiotic is released, alerting healthcare professionals that there is infection in the wound.

This is an important step in treating burns patients, particularly children, where infections can lead to toxic shock syndrome, a potentially fatal condition.

The €4.5 million European Commission funded project is a collaboration of 11 partners across Europe and Australia coordinated by Dr Renate Förch, at the Max-Planck-Institute for Polymer Research (Germany), which will develop the prototype dressing over four years.

The Bacteriosafe project includes chemists, cell biologists, clinicians and engineers. They will not only develop the dressing, but will also work with industry on a pre-pilot scale manufacturing process, so they could be available on the market within a few years after completion of the project.

University of Bath project leader, Dr Toby Jenkins said: "Your skin is normally home to billions of ‘friendly' bacteria, which it needs to stay healthy.

"The dressing is only triggered by disease-causing bacteria, which produce toxins that break open capsules containing the antibiotics and dye.

"This means that antibiotics are only released when needed, which reduces the risk of the evolution of new antibiotic-resistant super-bugs such as MRSA."

Dr Amber Young, a paediatric burn specialist at the South West UK Paediatric Burn Centre, based at Bristol's Frenchay Hospital, will be the clinical consultant on the project.

She said: "We're really excited about this project - every day we see young children who are seriously ill from burns who would hugely benefit from this research.

"Many people don't realise that a burn from a cup of tea can be deadly if it becomes infected.

"Conventional dressings have to be removed if the skin becomes infected, which slows healing and can be distressing for the child.

"This advanced dressing will speed up treatment because it is automatically triggered to release antibiotics only when the wound becomes infected, meaning that the dressing will not need to be removed, thereby increasing the chances of the wound healing without scarring.

"The colour change acts as an early warning system that infection is present, meaning we can treat it much faster, reducing the trauma to the child and cutting the time they have to spend in hospital."

The dressing could also be used for other types of wound, such as ulcers or by the military on the battlefield.

The researchers have already tested fabric coated with the nanocapsules, which are just one millionth of a millimetre in size. They have been shown to react specifically to harmful bacteria. Over the next four years the European team will be working on integrating the colour change technology into a suitable dressing and looking at cost effective routes for industrial production.

Case study - Baby Isambard Ebbutt
In September 2008 baby Isambard Ebbutt pulled a boiling hot cup of tea over himself causing 32 per cent burns across his face and body.

Isambard, who was just 13-months-old, was rushed to Frenchay Hospital in Bristol where he was treated by a team of experts at the South West Regional Paediatric Burns Service.

Luckily Isambard's skin healed fully and he did not need skin grafts. His family took Isambard home to Ellacombe, in Torquay, Devon, ten days after he was admitted.

Natalie Ebbutt, a mum of six, said: "I thought he was going to die, I just wanted my baby to live so I wanted him to be in the best place.

"It is so poignant that a cup of tea can kill, but I don't think that parents are aware of the damage that a cup of tea can do. I see adults walking around all the time with hot drinks near children."

Although Isambard recovered well from his burn, many children can develop potentially fatal infections after they are injured. The new dressing to be developed by the Bacteriosafe team will help prevent and treat infections before they take hold.

Mrs Ebbutt said: "I knew that the biggest chance of losing my child was if an infection took hold but all I could do was cross my fingers and hope for the best.

"To think now that there is a possibility of avoiding serious infection and complications with this project is amazing."

"It's a very exciting breakthrough, I am now all too aware of the dangers and what can happen if a burns wound gets an infection, it's devastating.

"There is never a day that goes by when we don't think how lucky we are to have him in such a perfect condition and see his smiling face."

View Video www.bath.ac.uk/news/2010/07/08/bacteriosafe-2/

####

About University of BathUniversity of Bath
The University of Bath is one of the UK’s leading universities, with an international reputation for quality research and teaching. Bath is ranked in the UK top ten of universities in both The Guardian University Guide and the Complete University Guide published by The Independent. The University values working collaboratively with others and has a global network of contacts in business, the professions, the public sector, and the voluntary sector. It also benefits from strong links with the local community.

For more information, please click here

Contacts:
For media enquiries:
Vicky Just
University Press Office
44 (0) 1225 386883
44 (0) 7966 341357

Copyright © University of BathUniversity of Bath

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoscale worms provide new route to nano-necklace structures March 29th, 2015

Solving molybdenum disulfide's 'thin' problem: Research team increases material's light emission by twelve times March 29th, 2015

A first glimpse inside a macroscopic quantum state March 28th, 2015

DFG to Establish One Clinical Research Unit and Five Research Units: New Projects to Investigate Complications in Pregnancy, Particle Physics, Nanoparticles, Implants and Transport Planning / Approximately 13 Million Euros in Funding for an Initial Three-Year Period March 28th, 2015

State-of-the-art online system unveiled to pinpoint metrology software accuracy March 27th, 2015

Videos/Movies

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Carbon nanotube fibers make superior links to brain: Rice University invention provides two-way communication with neurons March 25th, 2015

ASIC Development for MEMS Applications: A Platform Approach March 25th, 2015

Govt.-Legislation/Regulation/Funding/Policy

Nanoscale worms provide new route to nano-necklace structures March 29th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Possible Futures

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Nanotechnology Enabled Drug Delivery to Influence Future Diagnosis and Treatments of Diseases March 21st, 2015

Nanocomposites Market Growth, Industry Outlook To 2020 by Grand View Research, Inc. March 21st, 2015

Nanotechnology Drug Delivery Market in the US 2012-2016 : Latest Report Available by Radiant Insights, Inc March 16th, 2015

Academic/Education

LAMDAMAP 2015 hosted by the University March 26th, 2015

SUNY Poly & M+W Make Major Announcement: Major Expansion To Include M+W Owned Gehrlicher Solar America Corporation That Will Create up to 400 Jobs to Develop Solar Power Plants at SUNY Poly Sites Across New York State March 26th, 2015

SUNY POLY CNSE to Host First Ever Northeast Semi Supply Conference (NESCO) Conference Will Connect New and Emerging Innovators in the Northeastern US and Canada with Industry Leaders and Strategic Investors to Discuss Future Growth Opportunities in NYS March 25th, 2015

FEI Joins University of Ulm and CEOS on SALVE Project Research Collaboration: The Sub-Ångström Low Voltage Electron (SALVE) microscope should improve contrast and reduce damage on bio-molecules and two-dimensional nanomaterials, such as graphene March 18th, 2015

Nanomedicine

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Graphene reduces wear of alumina ceramic March 26th, 2015

Application of Graphene Oxide in Body Implants in Iran March 26th, 2015

Nanorobotic agents open the blood-brain barrier, offering hope for new brain treatments March 25th, 2015

Announcements

Nanoscale worms provide new route to nano-necklace structures March 29th, 2015

Solving molybdenum disulfide's 'thin' problem: Research team increases material's light emission by twelve times March 29th, 2015

A first glimpse inside a macroscopic quantum state March 28th, 2015

DFG to Establish One Clinical Research Unit and Five Research Units: New Projects to Investigate Complications in Pregnancy, Particle Physics, Nanoparticles, Implants and Transport Planning / Approximately 13 Million Euros in Funding for an Initial Three-Year Period March 28th, 2015

Nanobiotechnology

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Dolomite’s microfluidics technology ideal for B cell encapsulation March 24th, 2015

Tiny bio-robot is a germ suited-up with graphene quantum dots March 24th, 2015

TGAC's take on the first portable DNA sequencing 'laboratory': First remote laboratory allows researchers to conduct real-time anaylsis March 19th, 2015

Research partnerships

SUNY Poly & M+W Make Major Announcement: Major Expansion To Include M+W Owned Gehrlicher Solar America Corporation That Will Create up to 400 Jobs to Develop Solar Power Plants at SUNY Poly Sites Across New York State March 26th, 2015

ORNL-led team demonstrates desalination with nanoporous graphene membrane March 25th, 2015

New kind of 'tandem' solar cell developed: Researchers combine 2 types of photovoltaic material to make a cell that harnesses more sunlight March 24th, 2015

UW scientists build a nanolaser using a single atomic sheet March 24th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE