Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Revolutionary medical dressing uses nano-technology to fight infection

The dressing will be coated with nanocapsules that contain antibiotics and a dye (shown in red) that are broken open by toxins (green) produced by disease-causing bacteria (yellow)
The dressing will be coated with nanocapsules that contain antibiotics and a dye (shown in red) that are broken open by toxins (green) produced by disease-causing bacteria (yellow)

Abstract:
Researchers are using nanotechnology to develop a medical dressing which will detect and treat infection in wounds.

Revolutionary medical dressing uses nano-technology to fight infection

Bath | Posted on July 26th, 2010

Scientists at the University of Bath and the burns team at the Southwest UK Paediatric Burns Centre at Frenchay Hospital in Bristol are working together with teams across Europe and Australia to create an advanced wound dressing.

The dressing will work by releasing antibiotics from nanocapsules triggered by the presence of disease-causing pathogenic bacteria, which will target treatment before the infection takes hold.

The dressing will also change colour when the antibiotic is released, alerting healthcare professionals that there is infection in the wound.

This is an important step in treating burns patients, particularly children, where infections can lead to toxic shock syndrome, a potentially fatal condition.

The €4.5 million European Commission funded project is a collaboration of 11 partners across Europe and Australia coordinated by Dr Renate Förch, at the Max-Planck-Institute for Polymer Research (Germany), which will develop the prototype dressing over four years.

The Bacteriosafe project includes chemists, cell biologists, clinicians and engineers. They will not only develop the dressing, but will also work with industry on a pre-pilot scale manufacturing process, so they could be available on the market within a few years after completion of the project.

University of Bath project leader, Dr Toby Jenkins said: "Your skin is normally home to billions of ‘friendly' bacteria, which it needs to stay healthy.

"The dressing is only triggered by disease-causing bacteria, which produce toxins that break open capsules containing the antibiotics and dye.

"This means that antibiotics are only released when needed, which reduces the risk of the evolution of new antibiotic-resistant super-bugs such as MRSA."

Dr Amber Young, a paediatric burn specialist at the South West UK Paediatric Burn Centre, based at Bristol's Frenchay Hospital, will be the clinical consultant on the project.

She said: "We're really excited about this project - every day we see young children who are seriously ill from burns who would hugely benefit from this research.

"Many people don't realise that a burn from a cup of tea can be deadly if it becomes infected.

"Conventional dressings have to be removed if the skin becomes infected, which slows healing and can be distressing for the child.

"This advanced dressing will speed up treatment because it is automatically triggered to release antibiotics only when the wound becomes infected, meaning that the dressing will not need to be removed, thereby increasing the chances of the wound healing without scarring.

"The colour change acts as an early warning system that infection is present, meaning we can treat it much faster, reducing the trauma to the child and cutting the time they have to spend in hospital."

The dressing could also be used for other types of wound, such as ulcers or by the military on the battlefield.

The researchers have already tested fabric coated with the nanocapsules, which are just one millionth of a millimetre in size. They have been shown to react specifically to harmful bacteria. Over the next four years the European team will be working on integrating the colour change technology into a suitable dressing and looking at cost effective routes for industrial production.

Case study - Baby Isambard Ebbutt
In September 2008 baby Isambard Ebbutt pulled a boiling hot cup of tea over himself causing 32 per cent burns across his face and body.

Isambard, who was just 13-months-old, was rushed to Frenchay Hospital in Bristol where he was treated by a team of experts at the South West Regional Paediatric Burns Service.

Luckily Isambard's skin healed fully and he did not need skin grafts. His family took Isambard home to Ellacombe, in Torquay, Devon, ten days after he was admitted.

Natalie Ebbutt, a mum of six, said: "I thought he was going to die, I just wanted my baby to live so I wanted him to be in the best place.

"It is so poignant that a cup of tea can kill, but I don't think that parents are aware of the damage that a cup of tea can do. I see adults walking around all the time with hot drinks near children."

Although Isambard recovered well from his burn, many children can develop potentially fatal infections after they are injured. The new dressing to be developed by the Bacteriosafe team will help prevent and treat infections before they take hold.

Mrs Ebbutt said: "I knew that the biggest chance of losing my child was if an infection took hold but all I could do was cross my fingers and hope for the best.

"To think now that there is a possibility of avoiding serious infection and complications with this project is amazing."

"It's a very exciting breakthrough, I am now all too aware of the dangers and what can happen if a burns wound gets an infection, it's devastating.

"There is never a day that goes by when we don't think how lucky we are to have him in such a perfect condition and see his smiling face."

View Video www.bath.ac.uk/news/2010/07/08/bacteriosafe-2/

####

About University of BathUniversity of Bath
The University of Bath is one of the UK’s leading universities, with an international reputation for quality research and teaching. Bath is ranked in the UK top ten of universities in both The Guardian University Guide and the Complete University Guide published by The Independent. The University values working collaboratively with others and has a global network of contacts in business, the professions, the public sector, and the voluntary sector. It also benefits from strong links with the local community.

For more information, please click here

Contacts:
For media enquiries:
Vicky Just
University Press Office
44 (0) 1225 386883
44 (0) 7966 341357

Copyright © University of BathUniversity of Bath

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Particles from outer space are wreaking low-grade havoc on personal electronics February 19th, 2017

Liquid metal nano printing set to revolutionize electronics: Creating integrated circuits just atoms thick February 18th, 2017

Engineers shrink microscope to dime-sized device February 17th, 2017

Francis Alexander Named Deputy Director of Brookhaven Lab's Computational Science Initiative February 16th, 2017

Videos/Movies

Graphene foam gets big and tough: Rice University's nanotube-reinforced material can be shaped, is highly conductive February 13th, 2017

First ever blueprint unveiled to construct a large scale quantum computer February 3rd, 2017

The shape of melting in two dimensions: University of Michigan team uses Titan to explore fundamental phase transitions February 2nd, 2017

Metallic hydrogen, once theory, becomes reality: Harvard physicists succeed in creating 'the holy grail of high-pressure physics' January 28th, 2017

Govt.-Legislation/Regulation/Funding/Policy

Engineers shrink microscope to dime-sized device February 17th, 2017

Francis Alexander Named Deputy Director of Brookhaven Lab's Computational Science Initiative February 16th, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

Research reveals novel quantum state in strange insulating materials February 14th, 2017

Possible Futures

Particles from outer space are wreaking low-grade havoc on personal electronics February 19th, 2017

Liquid metal nano printing set to revolutionize electronics: Creating integrated circuits just atoms thick February 18th, 2017

Engineers shrink microscope to dime-sized device February 17th, 2017

Research opens door to smaller, cheaper, more agile communications tech February 16th, 2017

Academic/Education

Oxford Nanoimaging report on how the Nanoimager, a desktop microscope delivering single molecule, super-resolution performance, is being applied at the MRC Centre for Molecular Bacteriology & Infection November 22nd, 2016

The University of Applied Sciences in Upper Austria uses Deben tensile stages as an integral part of their computed tomography research and testing facility October 18th, 2016

Enterprise In Space Partners with Sketchfab and 3D Hubs for NewSpace Education October 13th, 2016

New Agricultural Research Center Debuts at UCF October 12th, 2016

Nanomedicine

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Meta-lenses bring benchtop performance to small, hand-held spectrometer: Game-changing nanostructure-based lenses allow smaller devices, increased functionality February 9th, 2017

Announcements

Particles from outer space are wreaking low-grade havoc on personal electronics February 19th, 2017

Liquid metal nano printing set to revolutionize electronics: Creating integrated circuits just atoms thick February 18th, 2017

Engineers shrink microscope to dime-sized device February 17th, 2017

Francis Alexander Named Deputy Director of Brookhaven Lab's Computational Science Initiative February 16th, 2017

Nanobiotechnology

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Nanobiotix appoints senior executive from pharmaceutical industry, as Chief Operating Officer: Oncology industry veteran to oversee operations and product commercialization February 8th, 2017

Research partnerships

Graphene foam gets big and tough: Rice University's nanotube-reinforced material can be shaped, is highly conductive February 13th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Highly sensitive gas sensors for volatile organic compound detection February 6th, 2017

UCLA physicists map the atomic structure of an alloy: Researchers measured the coordinates of more than 23,000 atoms in a technologically important material February 3rd, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project