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Scientists at the University of Missouri-St. Louis have received a $1.83 million, five-year R01 grant from the National Institutes of Health for their research on new antiviral drug candidates that they hope will be used to fight high-risk human papillomavirus, or HPV, the cause of most cervical cancer. The grant is called "Biophysics of Drug Interactions with Viral Episomes."
The lead investigator for the project is James Bashkin, research associate professor, who will collaborate with associate professors Cynthia Dupureur and Michael Nichols, all members of the Department of Chemistry & Biochemistry and the Center for Nanoscience at UMSL. These faculty members are collaborating with Chris Fisher of NanoVir, LLC, a drug discovery company dedicated to finding treatments for HPV, a primary cause of both abnormal pap smears and cervical cancer. Bashkin is a founding member of the company along with Fisher, who is director of biology at the company based in Kalamazoo, Michigan.
Nanotech Consortium Fosters Collaboration
CNS is very pleased to announce that at the recent Research Board meeting the Center for Nanoscience was awarded $124,500 for a period of 12 months to acquire an X-ray Diffraction/Small Angle X-ray Scattering instrument.
Other recent grants include:
DOE grant awarded to Eric Majzoub, PhD, CNS member and Assistant Professor, Physics & Astronomy
$2 Million for "Tunable Thermodynamics and Kinetics for Hydrogen Storage: Nanoparticle Synthesis using Ordered Polymer Templates"
Two NIH grants awarded to Chung Wong, PhD, CNS member and Assistant Professor, Chemistry & Biochemistry
$217,742 for "Compter-aided design of anti-cancer drugs targeting protein kinases"
$428,375 for "Anti-plague agents targeting YopH of Yersinia Pestis"
One NSF grant awarded to Janet Braddock-Wilking, PhD, CNS member and Associate Professor, Chemistry & Biochemistry
$343,000 for "Novel Metalloles containing heavy group 14 elements"
Small Grant award in the amount of $1,000
Research Board award to CNS director, Jingyue (Jimmy) Liu, PhD in the amount of $18,000
Sandia National Laboratories provided $100k/yr. for post doctoral support in the research area of "Development of Complex Ionic Hydrides for Hydrogen Storage Applications" to Eric Majzoub, PhD
Research Board award to Eric Majzoub, PhD in the amount of $20,000 for Hydrogen Storage research
Research award to Cindy Dupureur, PhD and Jim Bashkin, PhD in the amount of $12,000 for "Understanding Cervical Cancer Drugs"
Research award to Keith Stine, PhD in the amount of $6,000 for "Nanoporous Gold as a Support for Immunoassays in Cancer Diagnosis"
Research award to Michael Nichols, PhD in the amount of $12,500 for "Immune Receptors and the Alzheimer's Amyloid-Beta Peptide"
Small Grant award in the amount of $1,000
CNS Ph.D student Jinfeng Wang has received the Microscopy Society of America Presidential Scholar Award and a poster presentation Sigma Xi award for his poster on "Controlled Synthesis of ZnO Nanostructures"
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