Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nano-sand to revolutionise dermal drug delivery

Dr Nasrin Ghouchi-Eskandar
Dr Nasrin Ghouchi-Eskandar

Abstract:
A team of researchers at the University of South Australia have developed and patented new technology that allows for enhanced delivery of cosmetics and drugs through the skin.

Nano-sand to revolutionise dermal drug delivery

Australia | Posted on July 7th, 2010

Dr Nasrin Ghouchi-Eskandar from UniSA's Ian Wark Research Institute and her team are using nanoparticles of silica (essentially sand) to create longer lasting creams and cosmetics that control the release of drugs through specific layers of the skin.

The researchers are now seeking commercial partners to deliver the technology to market.

Skin creams are made of emulsions - tiny droplets of oily compounds dispersed in water, typically created using surfactants or detergents, but Dr Ghouchi-Eskandar and her colleagues have developed emulsions in which silica nanoparticles coat the droplets instead.

Dr Ghouchi-Eskandar says that the technology allows for greater control over the delivery of drugs through the skin than current methods.

"Coating the tiny emulsion droplets with silica increases the stability of the mixture, and makes it less likely that the active compounds inside will degrade or be released until we want it to happen," she says. "These are two significant challenges for formulation scientists."

"Using our method we found that, from a clinical point of view, drug delivery can be improved by adjusting release through the thickness of the coating. We can prepare both fast release, and slow or controlled release delivery systems."

Dr Ghouchi-Eskandar says that the technology is especially beneficial when a drug needs to be released at a specific time, or if releasing too much at once can lead to accumulation and toxic effects.

"It turns out that silica nanoparticles interact with skin cells in a way that significantly increases the delivery of drugs to specific skin layers," she says.

"Using nanoparticles, a higher concentration for the active ingredient is delivered and leakage into the bloodstream is limited. This is a great advantage for skin creams like sunscreen, for instance. It limits exposure of the rest of the body and any consequent toxicity.

"We have shown that nanoparticles will not pass through pig skin and in the near future we will be moving to trials using human skin."

Dr Ghouchi-Eskandar is one of 16 early-career scientists presenting their research for the first time, supported by Fresh Science, a national program sponsored by the Australian Government.

####

For more information, please click here

Contacts:
Media contact
Heather Leggett
office (08) 8302 0096
mobile 0434 078 819


Dr Nasrin Ghouchi-Eskandar
mobile 0408 851 695

Copyright © University of South Australia

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Picosun patents ALD nanolaminate to prevent electronics from overheating September 28th, 2016

Leti and Taiwanese Tech Organizations Sponsoring Workshop in Taipei on MEMS, IoT, Smart Lighting Applications, System Reliability & Security September 28th, 2016

Fighting cancer with sticky nanoparticles September 27th, 2016

Gold nanoparticles conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2 mediated pathway in breast cancer September 27th, 2016

Academic/Education

PHENOMEN is a FET-Open Research Project aiming to lay the foundations a new information technology September 19th, 2016

AIM Photonics Announces Release of Process Design Kit (PDK) for Integrated Silicon Photonics Design August 25th, 2016

Nanotech Security Featured by Simon Fraser University: Company's Anti-Counterfeiting Technology Developed With the Help of University's 4D LABS Materials Research Institute August 21st, 2016

W.M. Keck Foundation awards Cal State LA a $375,000 research and education grant August 4th, 2016

Nanomedicine

Fighting cancer with sticky nanoparticles September 27th, 2016

Gold nanoparticles conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2 mediated pathway in breast cancer September 27th, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

BBI Solutions launches innovative conjugate blocking technology that enhances signal intensity for lateral flow immunoassays September 20th, 2016

Announcements

Picosun patents ALD nanolaminate to prevent electronics from overheating September 28th, 2016

Leti and Taiwanese Tech Organizations Sponsoring Workshop in Taipei on MEMS, IoT, Smart Lighting Applications, System Reliability & Security September 28th, 2016

Fighting cancer with sticky nanoparticles September 27th, 2016

Gold nanoparticles conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2 mediated pathway in breast cancer September 27th, 2016

Patents/IP/Tech Transfer/Licensing

Picosun patents ALD nanolaminate to prevent electronics from overheating September 28th, 2016

NIST Patents Single-Photon Detector for Potential Encryption and Sensing Apps September 16th, 2016

For first time, carbon nanotube transistors outperform silicon September 8th, 2016

Industrial Nanotech, Inc. Provides Shareholder Update August 22nd, 2016

Personal Care/Cosmetics

Programmable materials find strength in molecular repetition May 23rd, 2016

Common nanoparticle has subtle effects on oxidative stress genes May 11th, 2016

NRL reveals novel uniform coating process of p-ALD April 21st, 2016

New ORNL method could unleash solar power potential March 16th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic