Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Chemical biologist and entrepreneur Carolyn Bertozzi awarded $500,000 Lemelson-MIT Prize

2010 $500,000 Lemelson-MIT Prize winner Carolyn Bertozzi. Courtesy of the Lemelson-MIT Program
2010 $500,000 Lemelson-MIT Prize winner Carolyn Bertozzi. Courtesy of the Lemelson-MIT Program

Abstract:
Lawrence Berkeley National Laboratory and University of California, Berkeley scientist honored for biotechnology innovations

Chemical biologist and entrepreneur Carolyn Bertozzi awarded $500,000 Lemelson-MIT Prize

Cambridge, MA | Posted on June 3rd, 2010

Internationally renowned chemical biologist Dr. Carolyn Bertozzi, whose research is applied worldwide in the biopharmaceutical industry, has achieved extraordinary success for her pioneering inventions in the field of biotechnology. The proven potential for future advances, and her current work manipulating processes within living cells to engineer their surfaces and secreted proteins, have won Bertozzi the prestigious 2010 $500,000 Lemelson-MIT Prize. She will accept the prize and present her accomplishments to the public at the Massachusetts Institute of Technology during the Lemelson-MIT Program's fourth-annual EurekaFest, a multi-day celebration of the inventive spirit, June 16-19.

Bertozzi's ability to identify unmet needs and craft innovative solutions has led to scientific advances with a broad range of applications. Chemical insights gleaned by Bertozzi have progressed efforts to diagnose and treat diseases such as cancer, inflammatory disorders such as arthritis, and infectious diseases like tuberculosis. Her multi-disciplinary approach has led to significant developments in the ability to engineer living cells and the proteins they produce with defined chemical properties. As a University of California, Berkeley Professor and Director of the Molecular Foundry at the Lawrence Berkeley National Laboratory, Bertozzi and her team study the biology of glycans, also known as complex carbohydrates, and develop nanotechnologies for probing biological systems.

Paving a Path in a Burgeoning Field

Bertozzi invented the world's first bioorthogonal chemical reaction, a technology for labeling biomolecules in living cells or animals. This form of labeling is a novel approach that allows researchers to specifically target cells and their functions for gene delivery and anti-tumor diagnostics. Bertozzi utilizes these reactions in her work toward imaging glycans on tumor cells, a technology that has the potential to facilitate early cancer detection. She also invented the genetically-encoded aldehyde tag technology, affording scientists with a simple method for precision protein engineering, creating an approach for the development of novel protein drugs.

Other projects Bertozzi holds patents for include a cell nanoinjector, an instrument that introduces molecules into living cells via a "nanoneedle," as well as artificial bone materials, targets for tuberculosis therapy and cell microarray platforms.

Leading the Way as a Mentor and Entrepreneur

Many of Bertozzi's revolutionary projects and findings have been achieved through her work as T.Z. and Irmgard Chu Distinguished Professor of Chemistry and Professor of Molecular and Cell Biology at the University of California, Berkeley, Senior Faculty Scientist in the Materials Science Division at the Lawrence Berkeley National Laboratory, Professor of Molecular and Cellular Pharmacology at the University of California, San Francisco, and as a Howard Hughes Medical Institute Investigator.

Bertozzi attributes a number of her innovations and research successes to the students and postdoctoral fellows whom she mentors - over the span of her career she has trained more than 130 coworkers including undergraduates, graduate students and postdoctoral fellows. She also created the University of California, Berkeley Chemical Biology Graduate Program.

"Carolyn Bertozzi takes scientific development to a new level; beyond her extraordinary gift as a researcher and innovator, she collaborates with her students to push into new frontiers," states Michael J. Cima, faculty director of the Lemelson-MIT Program. "As a mentor, she engages those around her to develop new, creative ideas, ensuring a future pipeline of scientists, inventors and policy makers."

Lab to Marketplace Commercialization and Adoption

As a testament to her teaching abilities and mentoring skills, as well as her true entrepreneurial spirit, Bertozzi founded biotech start-up Redwood Bioscience in 2008 with her former graduate student, Dr. David Rabuka. The company, structured around Bertozzi's advancements with the genetically-encoded aldehyde tag technology, is developing novel protein drugs with properties that conventional molecular biology approaches cannot achieve. The company was recently awarded a prestigious National Institutes of Health (NIH) Challenge Grant, bringing $1 million into the company over two years, and has raised funds from the private sector as well.

According to Professor Miquel Salmeron, director of the Materials Science Division at the Lawrence Berkeley National Laboratory, Bertozzi "transformed the field of chemical biology, creating new industries along the way, and bringing new innovations to fields as disparate as nanoscience, tuberculosis therapy, and bone tissue engineering." He adds, "She also has an outstanding record of teaching, mentorship, and service to the community."

With more than 225 publications to her name, a prestigious election to the National Academy of Sciences, and becoming one of the youngest recipients ever of a MacArthur "Genius" Award, Bertozzi has also been hailed with recognition by the American Chemical Society and selected as a Presidential Early Career Award in Science and Engineering.

Seeking Nominees for 2011 $500,000 Lemelson-MIT Prize

Applications for the 2011 $500,000 Lemelson-MIT Prize are now available at web.mit.edu/invent/a-prize.html. The annual prize honors an outstanding mid-career inventor who is dedicated to improving our world through technological invention and innovation.

The Lemelson-MIT Program recognizes the outstanding inventors and innovators transforming our world, and inspires young people to pursue creative lives and careers through innovation.

####

About Lemelson-MIT Program
Celebrating innovation, inspiring youth

The Lemelson-MIT Program recognizes the outstanding inventors and innovators transforming our world, and inspires young people to pursue creative lives and careers through innovation.

Jerome H. Lemelson, one of U.S. history’s most prolific inventors, and his wife Dorothy founded the Lemelson-MIT Program at the Massachusetts Institute of Technology in 1994. It is funded by The Lemelson Foundation and administered by the School of Engineering. The Foundation sparks, sustains and celebrates innovation and the inventive spirit. It supports projects in the U.S. and developing countries that nurture innovators and unleash invention to advance economic, social and environmentally sustainable development. To date The Lemelson Foundation has donated or committed more than U.S. $150 million in support of its mission. For more information about the Lemelson-MIT Program, visit web.mit.edu/invent.

For more information, please click here

Copyright © MIT

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New method allows for greater variation in band gap tunability: The method can change a material's electronic band gap by up to 200 percent January 31st, 2015

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Academic/Education

Rice's Naomi Halas to direct Smalley Institute: Optics pioneer will lead Rice's multidisciplinary science institute January 15th, 2015

SUNY Board Appoints Dr. Alain Kaloyeros as Founding President of SUNY Polytechnic Institute January 13th, 2015

CNSE's Smart System Technology & Commercialization Center Successfully Recertifies as ISO 9001:2008 January 12th, 2015

SUNY Poly Now Accepting Applications to the Colleges of Nanoscale Science and Engineering for Fall 2015: Full Scholarships Available to Incoming CNSE Students January 7th, 2015

Nanomedicine

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Made-in-Singapore rapid test kit detects dengue antibodies from saliva: IBN's MedTech innovation simplifies diagnosis of infectious diseases January 29th, 2015

Iranian Researchers Planning to Produce Edible Insulin January 28th, 2015

Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics January 28th, 2015

Announcements

New method allows for greater variation in band gap tunability: The method can change a material's electronic band gap by up to 200 percent January 31st, 2015

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

2015 Nanonics Image Contest January 29th, 2015

OCSiAl supports NanoART Imagery Contest January 23rd, 2015

EnvisioNano: An image contest hosted by the National Nanotechnology Initiative (NNI) January 22nd, 2015

Laser-generated surface structures create extremely water-repellent metals: Super-hydrophobic properties could lead to applications in solar panels, sanitation and as rust-free metals January 20th, 2015

Nanobiotechnology

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Spider electro-combs its sticky nano-filaments January 28th, 2015

Nanoshuttle wear and tear: It's the mileage, not the age January 26th, 2015

Engineering self-assembling amyloid fibers January 26th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE