Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Inspired by a cotton candy machine, engineers put a new spin on creating tiny nanofibers

Left: A diagram of the rotary jet spinner; upper right: The resulting "spun" nanofibers; bottom right: The nanofibers viewed at 10um. Credit: Kit Parker, Disease Biophysics Group at the Harvard School of Engineering and Applied Sciences
Left: A diagram of the rotary jet spinner; upper right: The resulting "spun" nanofibers; bottom right: The nanofibers viewed at 10um. Credit: Kit Parker, Disease Biophysics Group at the Harvard School of Engineering and Applied Sciences

Abstract:
Offering increased control and higher output, device could be a boon for industrial applications, from biocompatible materials to air filters

Inspired by a cotton candy machine, engineers put a new spin on creating tiny nanofibers

Cambridge, MA | Posted on May 25th, 2010

Hailed as a "cross between a high-speed centrifuge and a cotton candy machine," bioengineers at Harvard have developed a new, practical technology for fabricating tiny nanofibers.

The reference by lead author Mohammad Reza Badrossamay to the fairground treat of spun sugar is deliberate, as the device literally—and just as easily—spins, stretches, and pushes out 100 nanometer-diameter polymer-based threads using a rotating drum and nozzle.

The invention, reported in the May 24 online edition of Nano Letters, could be a boon for industry, with potential applications ranging from artificial organs and tissue regeneration to clothing and air filters. The researchers have filed a patent on their discovery.

"This is a vastly superior method to making nanofibers as compared to typical methods, with production output many times greater," says co-author Kit Parker, Thomas D. Cabot Associate Professor of Applied Science and Associate Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences (SEAS); a core faculty member of the Wyss Institue for Biologically Inspired Engineering at Harvard; and member of the Harvard Stem Cell Institute. "Our technique will be highly desirable to industry, as the simple machines could easily bring nanofiber production into any laboratory. In effect, with this technique we can mainstream nanotextiles."

By contrast, the most common method of creating nanofibers is through electrospinning, or sending a high voltage electric change into a droplet of polymer liquid to draw out long wisps of nanoscale threads. While effective, electrospinning offers limited control and low output of the desired fibers.

The Harvard researchers turned to a simpler solution, using rotary jet spinning. Quickly feeding and then rotating the polymer material inside a reservoir atop a controllable motor offers more control and greater yield.

When spun, the material stretches much like molten sugar does as it begins to dry into thin, silky ribbons. Just as in cotton candy production, the nanofibers are extruded through a nozzle by a combination of hydrostatic and centrifugal pressure.

The resulting pile of extruded fibers form into a bagel like shape about 10 cm in diameter.

"The new system offers fabrication of naturally occurring and synthetic polymers as well as a lot of control over fiber alignment and web porosity, hierarchical and spatial organization of fibrous scaffold and three-dimensional assemblies," says Badrossamay, a postdoctoral fellow in the Wyss Institute and member of Parker's lab at SEAS.

The researchers tested the new device using a variety of synthetic and natural polymers such as polylactic acid in chloroform, a biodegradable polymer created from corn starch or sugarcane that has been used as eco-friendly alternative to plastic in items like disposable cups.

Moreover, the rapid spinning method provides a high degree of flexibility as the diameter of the fibers can be readily manipulated and the structures can be integrated into an aligned three-dimensional structure or any shape simply by varying how the fibers are collected.

The shape of the fibers can also be altered, ranging from beaded to textured to smooth.

Parker's Disease Biophysics Group (DBG), which has extensive expertise in cardiac tissue engineering, also used the technology to form tissue engineering scaffolds, or artificial structures upon which tissue can form and grow.

Heart tissue from rats was integrated and aligned with the nanofibers, and, as seen in past studies, formed beating muscle.

"I was visiting the Society of Laproscopic Surgeons a couple of years ago to look at the equipment demos and it dawned on me that we needed to develop techniques to miniaturize scaffold production so we could do it in vivo. Our finding is the first step," explains Parker. "The initial testing suggests that our technique is incredibly versatile for both research and everyday applications. As rotary jet spinning does not require high voltage, it really brings nanofiber fabrication to everyone."

The researchers expect to further refine the process for tissue engineering applications and to look for opportunities to exploit the advance in other textile applications.


###

Badrossamay and Parker's co-authors include Holly Alice McIlwee a bioengineering graduate student at SEAS, and Josue A. Goss, the DBG laboratory manager who built the machine with Badrossamay.

The researchers acknowledge the support of the Nanoscale Science and Engineering Center (NSEC) at Harvard; the Materials Research Science and Engineering Center (MRSEC) at Harvard; and Harvard Center for Nanoscale Systems (CNS), and the Wyss Institute for Biologically Inspired Engineering at Harvard. The work was also funded in part by a National Science Foundation's (NSF) graduate research fellowship program.

####

For more information, please click here

Contacts:
Michael Patrick Rutter

617-496-3815

Copyright © Harvard University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New Biological Nano-Fertilizers Presented in Iran as Appropriate Replacements for Chemical Fertilizers April 18th, 2015

Iranian Foodstuff, Agricultural Industries Welcome Nanotechnology Packaging Bags April 18th, 2015

Nanocomposites Play Effective Role in Production of Smart Fibers April 18th, 2015

Dais Analytic Corporation Appoints Eliza Wang to Board of Directors: Company's Newest Director Brings Expertise in Commercial and Legal Matters Both in the United States and China; Joins on the Heels of Successful Business Development Trade Mission to China April 18th, 2015

Possible Futures

A glass fiber that brings light to a standstill: By coupling photons to atoms, light in a glass fiber can be slowed down to the speed of an express train; for a short while it can even be brought to a complete stop April 9th, 2015

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Nanotechnology Enabled Drug Delivery to Influence Future Diagnosis and Treatments of Diseases March 21st, 2015

Nanocomposites Market Growth, Industry Outlook To 2020 by Grand View Research, Inc. March 21st, 2015

Academic/Education

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem April 14th, 2015

UK National Graphene Institute Selects Bruker as Official Partner: World-Leading Graphene Research Facility Purchases Multiple Bruker AFMs April 7th, 2015

SUNY Poly CNSE and Title Sponsor SEFCU Name Capital Region Teams Advancing to the Final Round of the 2015 New York Business Plan Competition March 30th, 2015

LAMDAMAP 2015 hosted by the University March 26th, 2015

Nanomedicine

Optical resonance-based biosensors designed for medical applications April 18th, 2015

Nanocomposites Play Effective Role in Production of Smart Fibers April 18th, 2015

Novel nanoparticles could save soldiers' lives after explosions April 15th, 2015

Nanoparticles at specific temperature stimulate antitumor response: Dartmouth researchers identify precise heat to boost immune system against cancer tumors April 14th, 2015

Announcements

New Biological Nano-Fertilizers Presented in Iran as Appropriate Replacements for Chemical Fertilizers April 18th, 2015

Iranian Foodstuff, Agricultural Industries Welcome Nanotechnology Packaging Bags April 18th, 2015

Nanocomposites Play Effective Role in Production of Smart Fibers April 18th, 2015

Dais Analytic Corporation Appoints Eliza Wang to Board of Directors: Company's Newest Director Brings Expertise in Commercial and Legal Matters Both in the United States and China; Joins on the Heels of Successful Business Development Trade Mission to China April 18th, 2015

Textiles/Clothing

Nanocomposites Play Effective Role in Production of Smart Fibers April 18th, 2015

Inkjet-printed liquid metal could bring wearable tech, soft robotics April 8th, 2015

FibeRio and VF Corporation Form Strategic Partnership to Lead the Apparel and Footwear Markets in Nanofiber Technology April 8th, 2015

Scientists discover gecko secret March 16th, 2015

Nanobiotechnology

Protein Building Blocks for Nanosystems: Scientists develop method for producing bio-based materials with new properties April 17th, 2015

Study shows novel pattern of electrical charge movement through DNA April 14th, 2015

UAB researchers develop a harmless artificial virus for gene therapy April 8th, 2015

Pavel Levkin Is Granted Heinz Maier-Leibnitz Prize April 8th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE