Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > UGA researchers use patented SERS technique to rapidly, accurately detect rotavirus strains

Abstract:
Using nanotechnology and a patented signal enhancing technique developed at the University of Georgia, UGA researchers have discovered a rapid, sensitive and cost-effective method to detect and identify a number of rotavirus strains and genotypes in less than one minute with greater than 96 percent accuracy.

By Kat Gilmore

UGA researchers use patented SERS technique to rapidly, accurately detect rotavirus strains

Athens, GA | Posted on May 15th, 2010

In their study, Ralph A. Tripp and Jeremy D. Driskell, researchers in the College of Veterinary Medicine's department of infectious diseases, and Yiping Zhao and Richard Dluhy, researchers in the Franklin College of Arts and Sciences departments of physics and chemistry, utilized surface enhanced Raman scattering, or SERS, to detect and quantify Group A rotaviruses.


Group A rotaviruses are the leading cause of severe gastroenteritis in infants and young children, infecting approximately 130 million children annually.Rotavirus infections are responsible for approximately 2 million hospitalizations and more than 500,000 deaths each year, and are particularly burdensome on health care resources in developing countries. Clinical diagnostic tests currently used to detect rotavirus do not provide information on the genotypes, which is essential for aiding public health officials in monitoring epidemics, identifying novel strains and controlling disease.


Tripp and Driskell worked with the most commonly identified strains of rotavirus, provided by Carl D. Kirkwood of the Murdoch Childrens Research Institute, at the Royal Children's Hospital in Parkville, Australia, to show that SERS can detect and identify numerous virus strains and genotypes in less than 30 seconds, without the need to amplify the analyte for detection.Their technique requires no or minimal specimen preparation for analysis and uses minimal volumes of analyte.


"Nanotechnology has provided a considerable advance in diagnostic and prognostic capabilities," noted Tripp."The technology strengthens and expands current diagnostic applications by providing a means to enhance existing technology for novel applications such as SERS detection of viruses.The field of diagnostics and biosensing has been pushed dramatically forward by our ability to now amplify and detect the molecular fingerprints of pathogens as opposed to amplifying the pathogens for detection."


The findings from the UGA research team are important as most enteric viruses produce diseases that are not readily distinct from other pathogens and diagnostics are generally limited to attempts at viral culture, antibody-mediated antigen detection and polymerase chain reaction. These methods are cumbersome, often have limited breadth and sensitivity in detection and/or offer limited information on genotype.


SERS works by measuring the change in frequency of a near-infrared laser as it scatters off viral nucleic acid and protein components. This change in frequency, named the Raman shift for the scientist who discovered it in 1928, is as distinct as a fingerprint.


Funding for the study was provided by the U.S. Army Research Laboratory and the Georgia Research Alliance.The study was published in PLoS ONE on April 19.

####

About University of Georgia, College of Veterinary Medicine
The UGA College of Veterinary Medicine, founded in 1946, is dedicated to training future veterinarians, to conducting research related to animal diseases, and to providing veterinary services for animals and their owners.Research efforts are aimed at enhancing the quality of life for animals and people, improving the productivity of poultry and livestock, and preserving a healthy interface between wildlife and people in the environment they share.The college enrolls 102 students each fall out of more than 550 who apply.For more information, see www.vet.uga.edu.


The current UGA College of Veterinary Medicine Teaching Hospital, built in 1979, serves more than 18,000 patients per year in one of the smallest teaching hospitals in the United States.The college is currently working to raise $15 million toward building a new Veterinary Medical Learning Center, which will include a new teaching hospital as well as classrooms and laboratories that will allow for the education of more veterinarians.The goal is to increase enrollment to 150 when the Veterinary Medical Learning Center is built.Fore more information, see www.vet.uga.edu/giving/campaign.php.

For more information, please click here

Contacts:
Kat Gilmore
706/543-5485

Copyright © University of Georgia

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Iranian Scientists Use Waste Cotton Fibers to Produce Cellulose Nanoparticles July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Production of Toxic Gas Sensor Based on Nanorods July 28th, 2014

Govt.-Legislation/Regulation/Funding/Policy

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

Stanford team achieves 'holy grail' of battery design: A stable lithium anode - Engineers use carbon nanospheres to protect lithium from the reactive and expansive problems that have restricted its use as an anode July 27th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Possible Futures

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

Academic/Education

Haydale Announces Collaboration Agreement with Swansea University’s Welsh Centre for Printing and Coatings (WCPC) July 12th, 2014

STFC takes delivery of the 100th Hitachi Tabletop SEM in the UK July 3rd, 2014

Innovation Management and the Emergence of the Nanobiotechnology Industry July 1st, 2014

Albany NanoCollege Faculty Member Selected as Editor-in-Chief of the Prestigious Journal of Electronic Materials July 1st, 2014

Nanomedicine

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

Sensors

Production of Toxic Gas Sensor Based on Nanorods July 28th, 2014

Compact Vibration Harvester Power Supply with Highest Efficiency Opens Door to “Fix-and-Forget” Sensor Nodes July 23rd, 2014

Nano-sized Chip "Sniffs Out" Explosives Far Better than Trained Dogs: TAU researcher's groundbreaking sensor detects miniscule concentrations of hazardous materials in the air July 23rd, 2014

Tiny laser sensor heightens bomb detection sensitivity July 19th, 2014

Discoveries

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Iranian Scientists Use Waste Cotton Fibers to Produce Cellulose Nanoparticles July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

Measuring the Smallest Magnets July 28th, 2014

Announcements

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Iranian Scientists Use Waste Cotton Fibers to Produce Cellulose Nanoparticles July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Production of Toxic Gas Sensor Based on Nanorods July 28th, 2014

Tools

WITec to host the 11th Confocal Raman Imaging Symposium from September 29th - October 1st in Ulm, Germany July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Bruker Announces Acquisition of High-Speed, 3D Super-Resolution Fluorescence Microscopy Company Vutara July 28th, 2014

Malvern Instruments completes acquisition of MicroCal and announces purchase of Archimedes product from Affinity Biosensors July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE