Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nano-particle suspension in pharmaceutical mixing

Image shows phenytoin before (x10,000) and after (x100,000) thinky mixing
Image shows phenytoin before (x10,000) and after (x100,000) thinky mixing

Abstract:
Thinky mixers from Intertronics create nano-particle suspensions of medical compounds more reliably and quicker than traditional methods

Nano-particle suspension in pharmaceutical mixing

UK | Posted on May 11th, 2010

A new clever mixing process is announced by the people at Intertronics using the Thinky ARV-310 and Thinky ARV-5000 industrial non-contact "planetary" mixers for engineering compounds. In particular these machines are excellent in creating nano-particle suspensions of medical compounds more reliably and quicker than traditional methods. This can often overcome problems of dilution where materials have negligible water solubility and they enable mixing, dispersal and degassing in amounts as small as 0.5ml, up to large, laboratory level quantities.

The new process involves use of a Thinky mixer with zirconia balls which can pulverize poorly water soluble compounds such as medical drug doses using the over 2000 rpm planetary technology. In addition use of the ARV vacuum mixer enables complete elimination of all air bubbles. Commonly a pestle and mortar are used for oral dosage formulations. While this method is generally accepted and effective, this hand process is tedious and tiring, and lacks any degree of repeatability or consistent quality. The new technique is called "nh-Step". The nh-Step makes the mixing process easy, fast, improves physiochemical properties and it can be applied to many oral suspensions. For example, with an initial particle size of 18 micron, utilizing the "nh-Step" process the particle distribution was reduced to 2 microns after only 3 minutes with the Thinky's ARE-250.

The Thinky ARV-310 and Thinky ARV-5000 have the ability to process under vacuum, or under normal pressure, or even automatically switching into vacuum mode from non-vacuum state during the process. It is possible to set the desired vacuum level for different types of ingredients. For high-viscosity materials and materials for which a high degree of de-aeration is required, these are ideal mixers. These mixers can eliminate micron-sized bubbles, without the danger of foaming and messy spillage.

Further information regarding Intertronics' products can be found at www.intertronics.co.uk.

####

For more information, please click here

Contacts:
Peter Swanson
00 44 (0)1865 842842

Copyright © Intertronics

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Nanomedicine

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Materials/Metamaterials

Flexible Metamaterial Absorbers July 29th, 2014

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Iranian Scientists Use Waste Cotton Fibers to Produce Cellulose Nanoparticles July 29th, 2014

Announcements

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Tools

WITec to host the 11th Confocal Raman Imaging Symposium from September 29th - October 1st in Ulm, Germany July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Bruker Announces Acquisition of High-Speed, 3D Super-Resolution Fluorescence Microscopy Company Vutara July 28th, 2014

Malvern Instruments completes acquisition of MicroCal and announces purchase of Archimedes product from Affinity Biosensors July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE