Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UBC researchers design new biomaterial that mimics muscle elasticity

Abstract:
University of British Columbia researchers have cast artificial proteins into a new solid biomaterial that very closely mimics the elasticity of muscle.

UBC researchers design new biomaterial that mimics muscle elasticity

British Columbia | Posted on May 6th, 2010

The approach, detailed in the current issue of the journal Nature, opens new avenues to creating solid biomaterials from smaller engineered proteins, and has potential applications in material sciences and tissue engineering.

"There are obvious long-term implications for tissue engineers," says Hongbin Li, associate professor in the Dept. of Chemistry. "But at a fundamental level, we've learned that the mechanical properties we engineer into the individual proteins that make up this biomaterial can be translated into useful mechanical properties at the larger scale."

Li, Canada Research Chair in Molecular Nanoscience and Protein Engineering, and UBC colleague John Gosline, professor in the Dept. of Zoology, engineered the artificial proteins to mimic the molecular structure of titin.

Titin - also known as connectin - is a giant protein that plays a vital role in the passive elasticity of muscle. The engineered version-which resembles a chain of beads-is roughly 100 times smaller that titin.

The resulting rubber-like biomaterial showed high resilience at low strain and was tough at high strain — features that make up the elastic properties of muscles.

"A hallmark of titin-like proteins is that they unfold under a stretching force to dissipate energy and prevent damage to tissues by over-stretching," says Gosline. "We've been able to replicate one of the more unique characteristics exhibited by muscle tissues, but not all of them."

The mechanical properties of these biomaterials can be fine-tuned, providing the opportunity to develop biomaterials that exhibit a wide range of useful properties - including mimicking different types of muscles. The material is also fully hydrated and biodegradable.

UBC researchers Shanshan Lv, Daniel Dudek, Yi Cao and MM Balamurali also contributed to the study.

This research is supported by the Canadian Institutes of Health Research, the Canada Research Chairs program, the Canada Foundation for Innovation, the Michael Smith Foundation for Health Research, and the Natural Sciences and Engineering Research Council of Canada.

####

For more information, please click here

Contacts:
Hongbin Li
Department of Chemistry
Cell: 604.822.9669


John Gosline
Department of Zoology
Cell: 604.822.6745

Copyright © University of British Columbia

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Fewer defects from a 2-D approach August 15th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Oxford Instruments Plasma Technology announces a new partner in Korea August 15th, 2017

Possible Futures

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Fewer defects from a 2-D approach August 15th, 2017

2-faced 2-D material is a first at Rice: Rice University materials scientists create flat sandwich of sulfur, molybdenum and selenium August 14th, 2017

Engineers pioneer platinum shell formation process – and achieve first-ever observation August 11th, 2017

Academic/Education

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Graduate Students from Across the Country Attend Hands-on NanoCamp: Prominent scientists Warren Oliver, Ph.D., and George Pharr, Ph.D., presented a weeklong NanoCamp for hand-picked graduate students across the United States July 26th, 2017

The Physics Department of Imperial College, London, uses the Quorum Q150T to deposit metals and ITO to make plasmonic sensors and electric contact pads July 13th, 2017

Announcements

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Fewer defects from a 2-D approach August 15th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Oxford Instruments Plasma Technology announces a new partner in Korea August 15th, 2017

Nanobiotechnology

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

JPK reports on how the University of Glasgow is using their NanoWizard® AFM and CellHesion module to study how cells interact with their surroundings August 2nd, 2017

Research team bends individual tetrapod nanostructures August 2nd, 2017

Physicists gain new insights into nanosystems with spherical confinement: Enormous potential for the targeted delivery of pharmaceutical agents and the creation of tailored nanoparticles July 27th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project