Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > NanoVir, LLC Receives $3M Preclinical Development NIAID Grant

Abstract:
The National Institute of Allergy and Infectious Diseases (NIAID), an institute within the National Institutes of Health (NIH), has awarded a nearly $3 million small Business Technology Transfer Research (STTR) grant to NanoVir, LLC to support synthesis and pre-clinical development of lead antiviral compounds for treatment of human papillomavirus 16 (HPV16).

NanoVir, LLC Receives $3M Preclinical Development NIAID Grant

Kalamazoo, MI | Posted on May 5th, 2010

The grant to NanoVir, which spans three years, will support work at several collaborating institutions including NanoVir, the University of Missouri-St. Louis and Stanford Research Institute-International.

HPV16 is by far the major cause of cervical dysplasia and cancer. Currently, no effective treatment for the virus is available or anticipated. Centers for Disease Control and the World Health Organization typically refer to "follow up" observation and surgical intervention as the only options available for women infected by HPV16. Their reports rarely even suggest that antivirals might soon provide hope for treatment.

The STTR grant from the NIAID will support preclinical development of antiviral compounds, discovered and designed by NanoVir scientists, which possess excellent potency for treatment of HPV16 in human cell culture. These compounds, which target the HPV origin of replication (ori), a DNA regulatory region within the HPV genome, were designed, synthesized and tested with the support of a previous NIAID-AT-STTR Phase 1 grant awarded to NanoVir by the NIAID. They hold considerable potential as antiviral agents that have the potential to add an important tool to complement the HPV vaccines and allow both HPV+ and HPV- patients to be treated.

"This Phase 2 award will allow us to initiate the chemical scale-up and safety studies required by the Food and Drug Administration before clinical trials can be initiated. We're honored to have been awarded this grant, especially at a time when the peer-review and competition for such awards is so stringent," said Chris Fisher, co-founder and Director of Biology of NanoVir. "This is a significant validation of our approach and I believe that, as long as we hit our milestones, we will soon be in a position to enter clinical trials in HPV-positive women."

NanoVir, LLC is a Michigan-based company whose headquarters are located at the Southwest Michigan Innovation Center in Kalamazoo, Michigan. NanoVir is working on prevention of cervical cancer by developing antiviral agents for HPV, the cause of the vast majority of cervical cancer. The company is funded by the National Institutes of Health, under the National Institute of Allergy and Infectious Diseases.

####

About NanoVir
NanoVir, LLC is a drug discovery company dedicated to finding treatments for HPV, a primary cause of both abnormal pap smears and cervical cancer. NanoVir focuses on studying DNA-targeted therapies aimed to treat high-risk HPV infection before it can progress to cancer. NanoVir’s Kalamazoo site at the Southwest Michigan Innovation Center of Western Michigan University conducts cell-biology and virology studies, while its colleagues at the University of Missouri-St. Louis site carry out the related chemistry. The firm is currently concentrating on a topical treatment that could eliminate HPV infections.

About the Southwest Michigan Innovation Center
The Southwest Michigan Innovation Center is a 58,000-square-foot incubator/accelerator that provides wet-lab space, access to venture funding and comprehensive business support services to emerging companies in the life science industry. The Innovation Center is a state-of-the-art facility designed and staffed with high-tech scientific companies in mind. For more information, visit www.kazoosmic.com.

For more information, please click here

Contacts:
Send general inquires to:

Dr. Chris Fisher
NanoVir
4717 Campus Dr.
Kalamazoo, MI 49008
269.372.3261 office
269.372.3397 fax

Copyright © NanoVir

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Flexible Metamaterial Absorbers July 29th, 2014

ACS Biomaterials Science & Engineering™: Brand-new journal names editor July 29th, 2014

Harris & Harris Group Invests in Unique NYC Biotech Accelerator July 29th, 2014

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Govt.-Legislation/Regulation/Funding/Policy

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

Stanford team achieves 'holy grail' of battery design: A stable lithium anode - Engineers use carbon nanospheres to protect lithium from the reactive and expansive problems that have restricted its use as an anode July 27th, 2014

Nanomedicine

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Announcements

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

New imaging agent provides better picture of the gut July 25th, 2014

Hysitron is Awarded TWO R&D 100 Awards for Highly Innovative Technology Developments in the Areas of Extreme Environments and Biological Mechanical Property Testing July 23rd, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

EPFL Research on the use of AFM based nanoscale IR spectroscopy for the study of single amyloid molecules wins poster competition at Swiss Physics Society meeting July 22nd, 2014

Nanobiotechnology

Harris & Harris Group Invests in Unique NYC Biotech Accelerator July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE