Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Palos Physician's Research Advances New Therapy in Cartilage Repair

Dr. Nirav A. Shah, MD
Dr. Nirav A. Shah, MD

Abstract:
Dr. Nirav A. Shah, MD, an orthopaedic sports medicine surgeon affiliated with Palos Community Hospital is the first to design a new nanotechnology biomedical therapy that promotes the growth of new, stronger cartilage to aid in the treatment of joint injuries.

Palos Physician's Research Advances New Therapy in Cartilage Repair

Palos Heights, IL | Posted on April 16th, 2010

"In conjunction with current minimally invasive surgical techniques, we have discovered that we can accelerate and enhance cartilage repair by using a synthetically developed biomaterial which is composed of the amino acids that normally exist in humans," says Dr. Shah. "Translating this to a clinical solution may mean quicker return to athletic activities and work, and possibly prevent injuries from progressing to further cartilage degeneration or end-stage arthritis."

Cartilage damage is typically associated with work and athletic injuries, and commonly occurs in conjunction with ACL tears and other ligament problems. Damaged cartilage can lead to joint pain, swelling, stiffness and loss of mobility, and eventually to osteoarthritis, a condition that currently affects 27 million people in the United States. With an aging and increasingly active population, that figure is expected to grow.

Unlike bone, cartilage does not grow back, so treatments to regenerate the tissue are critical. Current cartilage repair techniques oftentimes lead to Type I collagen, which resembles scar tissue, Dr. Shah explains. However, normal cartilage is composed of Type II collagen. The self-assembling peptide molecules used by Dr. Shah and his colleagues are able to more closely mimic the nano-structure of natural cartilage.

Dr. Shah's research at Northwestern University focused on cartilage damage to the knee, but other joints - including the shoulder, elbow, hip and ankle - could potentially benefit from the new therapy. "While still in pre-clinical trials, we are hopeful we could use this as an adjunct to current minimally invasive surgical techniques to improve and accelerate cartilage repair and regeneration," Dr. Shah says. "In the long run, we hope this also will slow and possibly decrease the incidence of arthritis after these types of injuries."

Dr. Shah anticipates that clinical trials may begin in as little as five years. In the meantime, he recommends that patients and primary care physicians have a low threshold for seeking out the expertise of an orthopaedic sports medicine specialist if there is concern for a cartilage injury.

"It's important for patients to present early on to an orthopaedic sports medicine physician with acute knee or other joint injuries so proper treatment, whether surgical or non-surgical, can begin immediately to maximize recovery and achieve the best possible outcomes," says Dr. Shah. "While these biological advancements are exciting, if safe and expedient intervention is not performed, future or early surgical treatments may not be as effective."

Dr. Shah and his colleagues' findings were reported by the Proceedings of the National Academy of Science on February 1, and are also published in the April 7, issue of the Journal of the American Medical Association. This significant contribution to orthopaedics also was awarded first place at the 2008 Orthopaedic Research & Education Foundation (OREF) Midwest Resident Research Symposium. OREF is the research and education arm of the American Orthopaedic Association, the American Association of Orthopaedic Surgeons, and the Orthopaedic Research Society.

Born and raised in the suburbs of Chicago, Dr. Shah is an orthopaedic surgeon with a sub-specialty in sports medicine. He completed his residency at McGaw Medical Center at Northwestern University, Chicago, and received his medical degree from the University of Illinois College of Medicine. He completed his subspecialty training in sports medicine and arthroscopic surgery in Houston, TX, at Methodist Hospital and Baylor College of Medicine where he worked with high school, collegiate and professional teams. Dr. Shah is affiliated with Palos Community Hospital in Palos Heights, IL.

A leading provider of orthopaedic care, Palos Community Hospital unites orthopaedic surgical excellence with exceptional nursing care and comprehensive physical therapy to provide a multi-disciplinary approach that quickly and safely returns patients to an optimal level of functionality. This, combined with Palos Home Health Care services and the professional staff and state-of-the-art facilities of the Palos Health & Fitness Center, makes orthopaedic care at Palos Community Hospital one of the most comprehensive in the Chicago area.

####

About Palos Community Hospital
Palos Community Hospital is a 436-bed non-profit health care facility located in Palos Heights, IL. As one of the leading area hospitals, Palos has been serving the communities of Chicago's southwest suburbs for nearly 40 years. Its 530-affiliate physicians represent more than 40 specialties and subspecialties. Palos Community Hospital is operated in accordance with the Ethical and Religious Directives for Catholic Healthcare Facilities.

For more information, please click here

Contacts:
(708) 923-4000
12251 S. 80th Avenue
Palos Heights, IL 60463

Copyright © Palos Community Hospital

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

TCL Unveils First 65” TV Featuring QD Vision’s Color IQ™ Quantum Dot Technology: Emerging industry leader introduces expanded quantum dot TV lineup May 30th, 2015

Nanotech Secures Additional Patents in Advanced Security Features: New patented features gain attention from the banknote industry May 30th, 2015

New 'designer carbon' from Stanford boosts battery performance May 30th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Possible Futures

Global Carbon Nanotubes (CNT) Market Expected To Reach USD 3.42 Billion By 2022 May 29th, 2015

Global Nano-Enabled Packaging Market For Food and Beverages Will Reach $15.0 billion in 2020 May 26th, 2015

Simulations predict flat liquid May 21st, 2015

Nature inspires first artificial molecular pump: Simple design mimics pumping mechanism of life-sustaining proteins found in living cells May 19th, 2015

Self Assembly

Engineering Phase Changes in Nanoparticle Arrays: Scientists alter attractive and repulsive forces between DNA-linked particles to make dynamic, phase-shifting forms of nanomaterials May 25th, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

Advances in molecular electronics: Lights on -- molecule on: Researchers from Dresden and Konstanz succeed in light-controlled molecule switching April 20th, 2015

Carnegie Mellon chemists create tiny gold nanoparticles that reflect nature's patterns April 9th, 2015

Nanomedicine

New chip makes testing for antibiotic-resistant bacteria faster, easier: Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time May 28th, 2015

New electronic stent could provide feedback and therapy — then dissolve May 27th, 2015

Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Announcements

TCL Unveils First 65” TV Featuring QD Vision’s Color IQ™ Quantum Dot Technology: Emerging industry leader introduces expanded quantum dot TV lineup May 30th, 2015

Nanotech Secures Additional Patents in Advanced Security Features: New patented features gain attention from the banknote industry May 30th, 2015

New 'designer carbon' from Stanford boosts battery performance May 30th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Sports

Nanoparticles Used to Improve Mechanical, Thermal Properties of Cellulose Fibers April 23rd, 2015

Researchers use nanotechnology to engineer ACL replacements: Researchers created a tri-component, synthetic graft for reconstructing torn anterior cruciate ligaments December 30th, 2014

‘Small’ transformation yields big changes September 16th, 2014

CEA-Leti and CORIMA Team up on Force Sensors Integrated in Cycle Wheels to Measure Rider Power Output June 26th, 2014

Nanobiotechnology

New technique speeds nanoMRI imaging: Multiplexing technique for nanoscale magnetic resonance imaging developed by researchers in Switzerland cuts normal scan time from two weeks to two days May 28th, 2015

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Who needs water to assemble DNA? Non-aqueous solvent supports DNA nanotechnology May 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project