Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Paper Describes Functional Nanomaterials For Medical, Health Devices

Atomic layer deposition is especially useful for coating complex nanoscale structures. This image is a scanning electron micrograph obtained from a zinc oxide-coated nanoporous alumina membrane.
Atomic layer deposition is especially useful for coating complex nanoscale structures. This image is a scanning electron micrograph obtained from a zinc oxide-coated nanoporous alumina membrane.

Abstract:
A team led by researchers from North Carolina State University has published a paper that describes the use of a technique called atomic layer deposition to incorporate "biological functionality" into complex nanomaterials, which could lead to a new generation of medical and environmental health applications. For example, the researchers show how the technology can be used to develop effective, low-cost water purification devices that could be used in developing countries.

By Matt Shipman

Paper Describes Functional Nanomaterials For Medical, Health Devices

Raleigh, NC | Posted on March 22nd, 2010

"Atomic layer deposition is a technique that can be used to create thin films for coating metals or ceramics, and is especially useful for coating complex nanoscale structures," says Dr. Roger Narayan, the paper's lead author. "This paper shows how atomic layer deposition can be used to create biologically functional materials, such as materials that have antibacterial properties. Another example would be a material that does not bond to proteins in the body, which could be used for implantable medical sensors." Narayan is a professor in the joint biomedical engineering department of NC State's College of Engineering and the University of North Carolina at Chapel Hill.

One of the applications discussed in the paper is a material that could be used as a filter for point-of-use water purification. "This would be very helpful in the developing world, or in disaster situations - like Haiti - where people do not have access to safe water," Narayan says. "Over one billion people do not have access to safe water. This can lead to a variety of public health problems, including cholera and hepatitis."

Specifically, the researchers show that atomic layer deposition can be used to create a film for coating nanoporous membranes, which may be used for filtering out pathogenic bacteria. "The film could also provide antimicrobial functionality," Narayan says, "to neutralize bacteria."

In the study, the researchers found that membranes treated with one of these films were able to neutralize two common pathogens: E. coli and Staphylococcus aureus. The researchers are currently working with colleagues to assess how well the membranes perform against a variety of environmental bacteria. It's anticipated that these membranes could find use in a variety of medical and environmental health applications, such as hemodialysis filters and implantable sensors.

The research, "Atomic layer deposition-based functionalization of materials for medical and environmental health applications," is published in the March issue of the journal Philosophical Transactions of the Royal Society A. The research was funded by the National Science Foundation and the National Institutes of Health. The research was co-authored by Narayan, Dr. Nancy Monteiro-Riviere, professor of investigative dermatology and toxicology at the Center for Chemical Toxicology Research and Pharmacokinetics at NC State, Dr. Chunming Jin, a post-doctoral research associate at NC State, and Dr. Junping Zhang, a former post-doctoral research associate at NC State. Additional co-authors were from Kodak Research Laboratories, Argonne National Laboratory, North Dakota State University, National Yang-Ming University in Taiwan, and Taipei Medical University in Taiwan.

Note to editors: The study abstract follows.

"Atomic layer deposition-based functionalization of materials for medical and environmental health applications"

Authors: Roger J. Narayan, Nancy A. Monteiro-Riviere, Chunming Jin and Junping Zhang, North Carolina State University, et al.

Published: March 2010, Philosophical Transactions of the Royal Society A

Abstract: Nanoporous alumina membranes exhibit high pore densities, well-controlled pore sizes, uniform pore sizes and straight pores. Owing to these unusual properties, nanoporous alumina membranes are currently being considered for use in implantable sensor membranes and water purification membranes. Atomic layer deposition is a thin-film growth process that may be used to modify the pore size in a nanoporous alumina membrane while retaining a narrow pore distribution. In addition, films deposited by means of atomic layer deposition may impart improved biological functionality to nanoporous alumina membranes. In this study, zinc oxide coatings and platinum coatings were deposited on nanoporous alumina membranes by means of atomic layer deposition. PEGylated nanoporous alumina membranes were prepared by self-assembly of 1-mercaptoundec-11-yl hexa(ethylene glycol) on platinum-coated nanoporous alumina membranes. The pores of the PEGylated nanoporous alumina membranes remained free of fouling after exposure to human platelet-rich plasma; protein adsorption, fibrin networks and platelet aggregation were not observed on the coated membrane surface. Zinc oxide-coated nanoporous alumina membranes demonstrated activity against Escherichia coli and Staphylococcus aureus bacteria. The results of this work indicate that nanoporous alumina membranes may be modified using atomic layer deposition for use in a variety of medical and environmental health applications.

####

About North Carolina State University
With more than 31,000 students and nearly 8,000 faculty and staff, North Carolina State University is a comprehensive university known for its leadership in education and research, and globally recognized for its science, technology, engineering and mathematics leadership.

NC State students, faculty and staff are focused. As one of the leading land-grant institutions in the nation, NC State is committed to playing an active and vital role in improving the quality of life for the citizens of North Carolina, the nation and the world.

How? Researchers across the university and Centennial Campus are deeply engaged in making new, application-driven discoveries. As a major research university, NC State has the people —from undergraduate and graduate students to faculty — and the responsibility to advance knowledge, transfer technology, and discover and develop innovations that solve some of the world’s most pressing problems.

And we are. NC State’s research expenditures are approaching more than $325 million annually, with almost 70 percent of faculty engaged in sponsored research and 2,500 graduate students supported by research grants. NC State is ranked third among all public universities (without medical schools) in industry-sponsored research expenditures.

For more information, please click here

Contacts:
Matt Shipman
News Services
919.515.6386

Dr. Roger Narayan
919.696.8488

Copyright © North Carolina State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Thin films

LAMDAMAP 2015 hosted by the University March 26th, 2015

A new method for making perovskite solar cells March 16th, 2015

Engineers create chameleon-like artificial 'skin' that shifts color on demand March 12th, 2015

Researchers synthesize new thin-film material for use in fuel cells: Article in the journal APL Materials shows how to grow Bi2Pt2O7 pyrochlore, potentially a more effective cathode for future fuel cells March 10th, 2015

Govt.-Legislation/Regulation/Funding/Policy

Cooling massive objects to the quantum ground state April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

Rutgers, NIST physicists report technology with potential for sub-micron optical switches March 31st, 2015

SUNY Poly CNSE and Title Sponsor SEFCU Name Capital Region Teams Advancing to the Final Round of the 2015 New York Business Plan Competition March 30th, 2015

Possible Futures

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Nanotechnology Enabled Drug Delivery to Influence Future Diagnosis and Treatments of Diseases March 21st, 2015

Nanocomposites Market Growth, Industry Outlook To 2020 by Grand View Research, Inc. March 21st, 2015

Nanotechnology Drug Delivery Market in the US 2012-2016 : Latest Report Available by Radiant Insights, Inc March 16th, 2015

Nanomedicine

A novel way to apply drugs to dental plaque Nanoparticles release drugs to reduce tooth decay April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Nanomedicine shines light on combined force of nanomedicine and regenerative medicine March 31st, 2015

Prototype 'nanoneedles' generate new blood vessels in mice: Scientists have developed tiny 'nanoneedles' that have successfully prompted parts of the body to generate new blood vessels, in a trial in mice March 31st, 2015

Materials/Metamaterials

Wrapping carbon nanotubes in polymers enhances their performance: Scientists at Japan's Kyushu University say polymer-wrapped carbon nanotubes hold much promise in biotechnology and energy applications March 30th, 2015

DFG to Establish One Clinical Research Unit and Five Research Units: New Projects to Investigate Complications in Pregnancy, Particle Physics, Nanoparticles, Implants and Transport Planning / Approximately 13 Million Euros in Funding for an Initial Three-Year Period March 28th, 2015

Chemists make new silicon-based nanomaterials March 27th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Announcements

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Cooling massive objects to the quantum ground state April 1st, 2015

A novel way to apply drugs to dental plaque Nanoparticles release drugs to reduce tooth decay April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Environment

Young NTU Singapore spin-off clinches S$4.3 million joint venture with Chinese commercial giant March 23rd, 2015

New processing technology converts packing peanuts to battery components March 22nd, 2015

EU Funded PCATDES Project has completed its half-period with success March 19th, 2015

Are current water treatment methods sufficient to remove harmful engineered nanoparticle? March 10th, 2015

Water

Square ice filling for a graphene sandwich March 26th, 2015

ORNL-led team demonstrates desalination with nanoporous graphene membrane March 25th, 2015

Young NTU Singapore spin-off clinches S$4.3 million joint venture with Chinese commercial giant March 23rd, 2015

EU Funded PCATDES Project has completed its half-period with success March 19th, 2015

Nanobiotechnology

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

From tobacco to cyberwood March 31st, 2015

Wrapping carbon nanotubes in polymers enhances their performance: Scientists at Japan's Kyushu University say polymer-wrapped carbon nanotubes hold much promise in biotechnology and energy applications March 30th, 2015

'Atomic chicken-wire' is key to faster DNA sequencing March 30th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE