Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > MicroConstants Now Offers Nanoparticle Formulation Services

Abstract:
Unveils New Service Offering at the Society of Toxicology's 2010 Annual Meeting & ToxExpo(TM)

MicroConstants Now Offers Nanoparticle Formulation Services

Salt Lake City, UT | Posted on March 8th, 2010

MicroConstants, a GLP-compliant Contract Research Organization (CRO) specializing in bioanalytical and pharmacokinetic analysis, has acquired access to a new nanosizing technology that transforms water insoluble compounds into nanoparticles, making formulation preparation and dosing for toxicology studies easier. In multiple cases, our method has been proven to increase the gastro-intestinal absorption of highly insoluble compounds ensuring maximal oral exposure for toxicology studies.

Many commercially available medications and a large majority of New Chemical Entities (NCEs) produced are poorly soluble. For existing medications, this leads to costly and poorly absorbed medications that are minimally effective. For poorly soluble NCEs, higher doses, poor efficacy results and increased production costs often make them non-commercializable. Nanotechnologies have been proven as a valuable adjunct to the development of new therapeutics. Nanoparticles provide a much larger surface area thereby increasing the dissolution rate resulting in enhanced absorption. Nanosizing your compound elicits improved drug loading, exposure and bioavailability, and faster onset (earlier Tmax).

The patented, proprietary nanosizing process used at MicroConstants does not involve water or mechanical shear, so it is faster and more efficient than aqueous-based technologies. Furthermore, the process typically does not require the addition of excipients, leaving the pure Active Pharmaceutical Ingredient (API) ready for easy dispersion as a convenient suspension formulation. Our cost effective technique provides higher dose loading (50-60%), and is amendable to all routes of extravascular administration. The particle size is reproducible and the process is completely scalable.

If you are working with a difficult formulation or a compound with poor absorption, let MicroConstants transform your compound into nanoparticles. Visit us at booth 221 during the SOT Annual Meeting March 8-10, 2010 in Salt Lake City, Utah to learn more.

####

About MicroConstants
MicroConstants is a GLP-compliant Contract Research Organization (CRO) dedicated to providing premier quality bioanalytical, drug metabolism, pharmacokinetic, formulation and immunoassay support services to pharmaceutical and biotech companies worldwide. We are the largest bioanalytical LC/MS/MS service provider on the West Coast, and specialize in method development, method validation and sample analysis.

For more information about our nanoparticle formulation services, or any of the services offered by MicroConstants, please visit our website at www.microconstants.com.

For more information, please click here

Contacts:
MicroConstants
9050 Camino Santa Fe
San Diego, CA 92121
TOLL FREE: +1 (866) 232-9497
PH: +1 (858) 652-4600
FAX: +1 (858) 652-4699

Copyright © PrNewswire

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Down to the quantum dot: Jülich researchers develop ultrahigh-resolution 3-D microscopy technique for electric fields July 7th, 2015

Miniature Technology, Large-Scale Impact: Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology - See more at: http://www.news.ucsb.edu/2015/015744/miniature-technology-large-scale-impact#stha July 7th, 2015

Transition from 3 to 2 dimensions increases conduction, MIPT scientists discover July 6th, 2015

A Stretchy Mesh Heater for Sore Muscles July 6th, 2015

Products

Philips Introduces Quantum Dot TV with Color IQ™ Technology from QD Vision: Manufacturer is first to offer quantum dot displays for both TVs and monitors June 30th, 2015

Dais Analytic Unveils New Version of Aqualyte Membrane Technology: Updates to the Basis of the Company's Industry-Changing Nanotechnology Designed to Strengthen Position in Global Air, Energy, and Water Markets June 26th, 2015

Industrial Nanotech, Inc. Announces Launch of Heat Shield(TM) EPX4 Thermal Insulation and Chemical Resistant Coating June 12th, 2015

Industrial Nanotech, Inc. Announces Official Launch of the Eagle Platinum Tile™ May 19th, 2015

Nanomedicine

Miniature Technology, Large-Scale Impact: Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology - See more at: http://www.news.ucsb.edu/2015/015744/miniature-technology-large-scale-impact#stha July 7th, 2015

A Stretchy Mesh Heater for Sore Muscles July 6th, 2015

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Announcements

Down to the quantum dot: Jülich researchers develop ultrahigh-resolution 3-D microscopy technique for electric fields July 7th, 2015

Miniature Technology, Large-Scale Impact: Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology - See more at: http://www.news.ucsb.edu/2015/015744/miniature-technology-large-scale-impact#stha July 7th, 2015

Transition from 3 to 2 dimensions increases conduction, MIPT scientists discover July 6th, 2015

A Stretchy Mesh Heater for Sore Muscles July 6th, 2015

Patents/IP/Tech Transfer/Licensing

GLOBALFOUNDRIES Completes Acquisition of IBM Microelectronics Business: Transaction adds differentiating technologies, world-class technologists, and intellectual property July 1st, 2015

NEI Announces the Issuance of Multiple Patents on Self-Healing & Superhydrophobic Coatings June 30th, 2015

Solegear Further Strengthens its Product Development Team: New Hire Seeks to Create New, Disruptive, Sustainable Materials June 17th, 2015

High-tech nanofibres could help nutrients in food hit the spot June 17th, 2015

Events/Classes

BBC World Service to broadcast Forum discussion on graphene July 6th, 2015

Nanometrics to Announce Second Quarter Financial Results on July 23, 2015 July 2nd, 2015

Leti Announces Launch of First European Nanomedicine Characterisation Laboratory: Project Combines Expertise of 9 Partners in 8 Countries to Foster Nanomedicine Innovation and Facilitate Regulatory Approval July 1st, 2015

How Graphene–based Nanomaterials and Films Revolutionize Science Explained in July 9 Webinar Hosted by Park Systems June 29th, 2015

Nanobiotechnology

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Engineering the world’s smallest nanocrystal July 2nd, 2015

Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015

Newly-Developed Biosensor in Iran Detects Cocaine Addiction June 23rd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project