Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Argonne scientists discover novel materials approach to fighting cancer

Abstract:
Scientists from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago Medical Center are shaking up the world of materials science and cancer research on the cover of the February 2010 issue of the journal Nature Materials.

Argonne scientists discover novel materials approach to fighting cancer

Chicago, IL | Posted on March 1st, 2010

Brain cancer is notoriously difficult to treat with standard cancer-fighting methods, so scientists have been looking outside standard medicine and into nanomaterials as a treatment alternative.

"Our mission is to develop advanced ‘smart' materials with unique properties," said Elena Rozhkova, a nanoscientist with Argonne's Center for Nanoscale Materials. "These efforts are directed to the improvement of the national quality of life, including creating novel medical technologies."

A team of scientists, including Rozhkova, Dong-Hyum Kim, Valentyn Novosad, Tijana Rajh and Samuel Bader from Argonne, and Maciej Lesniak and Ilya Ulasov from the University of Chicago Brain Tumor Center, developed a technique that uses gold-plated iron-nickel microdiscs connected to brain-cancer-seeking antibodies to fight cancer. The microdiscs are an example of a nanomagnetic material and can be used to probe cell mechanics and activate mechanosensitive ion channels, as well as to advance cancer therapies.

The discs posses a spin-vortex ground state and sit dormant on the cancer cell until a small alternating magnetic field is applied and the vortices shift, creating an oscillation. The energy from the oscillation is transferred to the cell and triggers apoptosis, or "cell suicide."

Since the antibodies are attracted only to brain cancer cells, the process leaves surrounding healthy cells unharmed. This makes them unlike traditional cancer treatment methods, such as chemotherapy and radiation, which negatively affect both cancer and normal healthy cells.

"We are very excited about this melding of materials and life sciences, but we are still in the very early research stages," materials scientist Valentyn Novosad said. "We are planning to begin testing in animals soon, but we are several years away from human trials. Everything is still experimental."

Along with continued testing and research of the treatment, scientists also have to examine any possible side effects that have been so far unseen in the laboratory.

"The use of nanomaterials for cancer treatment is not a new concept, but the ability to kill the cells without harming surrounding healthy cells has incredible potential," Rozhkova said. "Such a topic can only be approached with the expertise of markedly differing disciplines such as physics, chemistry, biology and nanotechnology and can make a great impact in important areas of science and modern advanced technologies."

####

About Argonne National Laboratory
Argonne National Laboratory seeks solutions to pressing national problems in science and technology. The nation's first national laboratory, Argonne conducts leading-edge basic and applied scientific research in virtually every scientific discipline. Argonne researchers work closely with researchers from hundreds of companies, universities, and federal, state and municipal agencies to help them solve their specific problems, advance America 's scientific leadership and prepare the nation for a better future. With employees from more than 60 nations, Argonne is managed by UChicago Argonne, LLC for the U.S. Department of Energy's Office of Science.

For more information, please click here

Contacts:
Brock Cooper
630/252-5565

Copyright © Argonne National Laboratory

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Bosch announces high-performance MEMS acceleration sensors for wearables June 27th, 2017

Nanometrics to Participate in the 9th Annual CEO Investor Summit 2017: Accredited investor and publishing research analyst event held concurrently with SEMICON West and Intersolar 2017 in San Francisco June 27th, 2017

NMRC, University of Nottingham chooses the Quorum Q150 coater for its reliable and reproducible film thickness when coating samples with iridium June 27th, 2017

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

Videos/Movies

Tiny bubbles provide tremendous propulsion in new microparticles research-Ben-Gurion U. June 21st, 2017

Graphene and quantum dots put in motion a CMOS-integrated camera that can see the invisible May 29th, 2017

Controlling 3-D behavior of biological cells using laser holographic techniques May 26th, 2017

Zap! Graphene is bad news for bacteria: Rice, Ben-Gurion universities show laser-induced graphene kills bacteria, resists biofouling May 22nd, 2017

Possible Futures

Atomic imperfections move quantum communication network closer to reality June 25th, 2017

Research accelerates quest for quicker, longer-lasting electronics: UC Riverside-led research makes topological insulators magnetic well above room temperatures June 25th, 2017

U.S. Air Force Research Lab Taps IBM to Build Brain-Inspired AI Supercomputing System: Equal to 64 million neurons, new neurosynaptic supercomputing system will power complex AI tasks at unprecedented speed and energy efficiency June 23rd, 2017

Rice U. chemists create 3-D printed graphene foam June 22nd, 2017

Academic/Education

Oxford Instruments congratulates Lancaster University for inaugurating the IsoLab, built for studying quantum systems June 20th, 2017

The 2017 Winners for Generation Nano June 8th, 2017

MIT Energy Initiative awards 10 seed fund grants for early-stage energy research May 4th, 2017

Bar-Ilan University to set up quantum research center May 1st, 2017

Nanomedicine

Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017

Learning with light: New system allows optical “deep learning”: Neural networks could be implemented more quickly using new photonic technology June 12th, 2017

Mussels add muscle to biocompatible fibers: Rice University chemists develop hydrogel strings using compound found in sea creatures June 9th, 2017

Making vessels leaky on demand could aid drug delivery:Rice University scientists use magnets and nanoparticles to open, close gaps in blood vessels June 8th, 2017

Discoveries

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

Atomic imperfections move quantum communication network closer to reality June 25th, 2017

Research accelerates quest for quicker, longer-lasting electronics: UC Riverside-led research makes topological insulators magnetic well above room temperatures June 25th, 2017

Rice U. chemists create 3-D printed graphene foam June 22nd, 2017

Announcements

Bosch announces high-performance MEMS acceleration sensors for wearables June 27th, 2017

Nanometrics to Participate in the 9th Annual CEO Investor Summit 2017: Accredited investor and publishing research analyst event held concurrently with SEMICON West and Intersolar 2017 in San Francisco June 27th, 2017

NMRC, University of Nottingham chooses the Quorum Q150 coater for its reliable and reproducible film thickness when coating samples with iridium June 27th, 2017

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

Nanobiotechnology

Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017

Mussels add muscle to biocompatible fibers: Rice University chemists develop hydrogel strings using compound found in sea creatures June 9th, 2017

Making vessels leaky on demand could aid drug delivery:Rice University scientists use magnets and nanoparticles to open, close gaps in blood vessels June 8th, 2017

Nanobiotix's promising data from Phase I/II head and neck cancer trial presented at ASCO June 5th, 2017

Alliances/Trade associations/Partnerships/Distributorships

U.S. Air Force Research Lab Taps IBM to Build Brain-Inspired AI Supercomputing System: Equal to 64 million neurons, new neurosynaptic supercomputing system will power complex AI tasks at unprecedented speed and energy efficiency June 23rd, 2017

Cambridge Nanotherm partners with Inabata for global sales and distribution June 20th, 2017

Thought Leaders and Experts Join National Graphene Association Advisory Board June 16th, 2017

Microsoft, Purdue collaborate to advance quantum computing May 30th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project