Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > RUSNANO Takes a Medical Track: Investment in Manufacturing Drugs in Organic Nanopacks

Abstract:
A project to produce a number of pharmaceuticals— anti-inflammatory drugs, diuretics, and statins in phospholipid capsules with extremely small particles (less than 30 nm) recently won approval from the Supervisory Council of RUSNANO. The total budget for the project is 831 million rubles. RUSNANO will invest 341 million rubles.

RUSNANO Takes a Medical Track: Investment in Manufacturing Drugs in Organic Nanopacks

Russia | Posted on January 19th, 2010

As a result of implementing the project, in 2010-2015 a Russian company will establish original commercial production of medications that are without parallel in the entire world. The unique technology for fusing the most dissimilar drug substances in phospholipid nanoparticles was developed in the Russian Federation. It will enable the project company to enter the market with innovative and highly effective forms of medications in only one to two years, with minimal risk, and with a minimal budget.

The capsules of drug nanoparticles (micelles) are composed of phospholipids—natural fat molecules that form in cell membranes. Phospholipid nanoparticles easily penetrate the cells and free the active drug ingredients precisely where they are needed. Phagocytes and other cells of the human defense system that imbibe objects foreign to the organism are unable to distinguish the 15-nm to 25-nm drug nanoparticles. Therefore, the nanoparticles circulate in the blood stream longer and leave it largely in those places where the vessel walls are most penetrable. Those most penetrable places—for example, the locus of inflammation or tumor—often require therapeutic intervention.

The scientific investigator, the body responsible for conducting experimental work and medical trials for the project, will be the V.N. Orekhovich Institute of Biomedical Chemistry of the Russian Academy of Medical Sciences. Its chief, Academician Alexander Archakov, is one of the world's leading specialists in medical nanobiotechnology. Project company EkhoBiPharmDubna, located in the special economic zone in Dubna, Moscow Oblast, will produce the nanomedications.

"Drug production and supplies to the drug delivery system is an innovative area of the pharmaceutical industry worldwide," noted Academician Archakov. "The scientific group in this project has already made particularly valuable contribution to phospholipid-carrying nanosystems, making it possible to imbed in phospholipid micelles non-soluble substances—nearly 75 percent of all medications."

The first series of drugs are expected to enter production and sale in 2011-2012. These will be nanoforms of indometacin (a non-steroid anti-inflammatory drug), prednisolone (a steroid anti-inflammatory drug), and chlorine-E6 (an active ingredient in photosensitizers—medications used to treat a long list of illnesses in oncology, otolaryngology, dermatology, dentistry, and surgery with an innovative method of photodynamic therapy.) In the second series of medication, 2012-2015, the project company plans to issue nanoforms of verospiron (a potassium-sparing diuretic) and the innovative statin nanophospholip (a drug that decreases the level of cholesterol in the blood and helps fight cardiovascular diseases).

RUSNANO Managing Director Olga Shpichko commented: "Drugs produced with this technology are going to be highly competitive in the marketplace because of the originality and universality of the know-how. The modest price of nanomedications and their considerably greater effectiveness than traditional counterparts will make the new drugs available to a huge portion of the populace. Therefore, this project has tremendous social importance."

####

About RUSNANO
The Russian Corporation of Nanotechnologies (RUSNANO) was established in 2007 by the Federal law ¹ 139-FZ to enable Government policy in the field of Nanotechnology.

To accomplish this task, RUSNANO co-invests in nanotechnology industry projects that have high commercial potential or social benefit. Early-stage investment by RUSNANO lowers the risk of its investment partners from the private sector.

RUSNANO participates in building nanotechnology infrastructure, which includes the nanotechnology centers of excellence, business incubators and early stage investment funds. RUSNANO provides scientific and educational programs that are required for its investment projects to succeed, and also supports the popularization of nanoscience and nanotechnology. RUSNANO selects promising spheres for investment based on longer-term foresight created by the leading Russian and world experts.

To assist the Russian nanotechnology industry advance to the global market and strengthening of its international links RUSNANO develops partnerships with the leading nanotechnology centers in the world and organizes the annual Nanotechnology International Forum in Russia.

For more information, please click here

Contacts:
Anna Fradkova, press-secretary of the international press office
P.: +7 495 5424444 add.1424
M.: +7 985 7299860

Copyright © RUSNANO

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Laboratorial Performance of Nanocomposite Membrane Improved in Water Purification July 28th, 2015

Perfect Optical Properties in Production of Aluminum Oxide Colloid Nanoparticles July 28th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

'Seeing' molecular interactions could give boost to organic electronics July 28th, 2015

Govt.-Legislation/Regulation/Funding/Policy

New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

Researchers predict material with record-setting melting point July 27th, 2015

Reshaping the solar spectrum to turn light to electricity: UC Riverside researchers find a way to use the infrared region of the sun's spectrum to make solar cells more efficient July 27th, 2015

Nanomedicine

Stretching the limits on conducting wires July 25th, 2015

UT Dallas nanotechnology research leads to super-elastic conducting fibers July 24th, 2015

Nanopaper as an optical sensing platform July 23rd, 2015

Albany College of Pharmacy and Health Sciences to Host One Week Symposium on Nanomedicine July 23rd, 2015

Announcements

Laboratorial Performance of Nanocomposite Membrane Improved in Water Purification July 28th, 2015

Perfect Optical Properties in Production of Aluminum Oxide Colloid Nanoparticles July 28th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

'Seeing' molecular interactions could give boost to organic electronics July 28th, 2015

Nanobiotechnology

New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015

Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015

Programming adult stem cells to treat muscular dystrophy and more by mimicking nature July 22nd, 2015

Biophotonics - Global Strategic Business Report 2015 July 21st, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project