Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Georgia Institute of Technology selects Nanosight to study the size of nanogels used in developing drug delivery vehicles

Members of the Lyon Group at Georgia Institute of Technology discuss results from the NanoSight LM-20 system. (main user, Michael Smith, is in the striped shirt)
Members of the Lyon Group at Georgia Institute of Technology discuss results from the NanoSight LM-20 system. (main user, Michael Smith, is in the striped shirt)

Abstract:
The School of Chemistry & Biochemistry at Georgia Institute of Technology has chosen the NanoSight LM-20 system to help in the characterisation of dimensional changes of nanogels used in the development of drug delivery vehicles for macromolecular therapeutics.

Georgia Institute of Technology selects Nanosight to study the size of nanogels used in developing drug delivery vehicles

Salisbury, UK | Posted on January 13th, 2010

The GIT research group of Professor Andrew Lyon works on the development and implementation of new, environmentally responsive (or "smart") materials for photonic materials, bioanalysis, and biomimetics. The approach the group is taking is to design hydrogel nanoparticles that undergo large changes in their chemical, mechanical, optical, or electrical makeup in response to a chemical stimulus, biomolecular interaction, or electromagnetic field; such materials can be viewed as amplifiers or sensitisers of the environmental event. As a result of their environmental sensitivity, nanogels have potential in a number of applications.

Principal user is PhD candidate, Michael Smith. He has been very impressed with the instrument. "The NanoSight has been an enabling tool for us in the characterisation of dilute nanogel samples, where DLS fails to produce reliable correlation data. For instance, in our recent investigations of degradable nanogels, we used the NanoSight for sizing and number density estimation throughout the erosion reaction. In these studies, sample concentrations were typically very low at later stages of the degradation reaction (due to particle loss). Similarly, the NanoSight is effective at measuring the fractionated samples from Asymmetrical flow field-flow fractionation (where samples are greatly diluted following separation)."

Smith continued, "the LM-20 has also been used to characterize a variety of other particle types in the group in conjunction with other light scattering and microscopy methods, to provide topological information for various nanoparticles."

NanoSight's approach, known as Nanoparticle Tracking Analysis (NTA), has been shown to be ideally suited to both research and process control use. The system is an extremely powerful nanoscale research and development tool for looking a broad range of particle types and concentrations.

To learn more about nanoparticle characterisation using NTA, please visit the company's website (www.nanosight.com) and register for the latest issue of NanoTrail, the company's electronic newsletter.

####

About NanoSight
NanoSight Ltd, of Salisbury, UK, is the world leading provider of instruments for the optical detection and real time analysis of sub-micron particles. The Company supplies unique instruments for nanoparticle analysis in the sub-micron region that go far beyond existing light scattering techniques in the characterisation of polydispersed systems. NanoSight delivers direct visualisation of individual nanoscale particles in suspension from which independent quantitative estimation of particle size, size distribution and concentration are immediately obtained. In viral titre assessment, NanoSight produces more accurate concentration results than plaque assay, and delivers them within minutes, validating the results with a unique real-time image. Founded in 2004, the company currently has more than 200 systems in service worldwide, having begun commercial sales in 2006.

The Company has a growing base of users worldwide, including BASF, BP GlaxoSmithKline, Novartis, 3M Corp, Roche, Solvay & Unilever and many universities.

For more information, please click here

Contacts:
NanoSight Limited
Minton Park
London Road
Amesbury SP4 7RT
T +44 (0) 1980 676060
F +44 (0) 1980 624703


NetDyaLog Limited
39 de Bohun Court
Saffron Walden
Essex CB10 2BA
T +44 (0) 1799 521881
M +44 (0) 7843 012997

Copyright © NanoSight

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Searching for a nanotech self-organizing principle May 1st, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Nanomedicine

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Announcements

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Tools

Exploring phosphorene, a promising new material April 29th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Chemists use DNA to build the world's tiniest thermometer April 27th, 2016

Bruker Introduces Dimension FastScan Pro Industrial AFM: Providing Nanometer-Resolution at High Scan Rates for up to 300-mm Samples April 26th, 2016

Environment

Team builds first quantum cascade laser on silicon: Eliminates the need for an external light source for mid-infrared silicon photonic devices or photonic circuits April 21st, 2016

Atomically thin sensor detects harmful air pollution in the home April 18th, 2016

Catalyst could make production of key chemical more eco-friendly April 10th, 2016

Nanoporous material's strange "breathing" behavior April 7th, 2016

Nanobiotechnology

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

New-Contracts/Sales/Customers

Nanometrics Achieves Record 3D-NAND Bookings Quarter: A Record 3D-NAND Bookings Quarter, both in Aggregate and for Each of Three Key Customers March 28th, 2016

Keystone Nano selected by National Cancer Institute to participate in BIO March 23rd, 2016

Heriot-Watt's Institute of Photonics & Quantum Sciences uses the Deben Microtest 2 kN tensile stage to characterise ceramics and engineering plastics January 21st, 2016

Industrial Nanotech, Inc. Begins Supplying One of World's Largest Pulp and Paper Product Companies with Patented Energy Saving and Protective Coatings for Heat Process Equipment January 4th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic