Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Georgia Institute of Technology selects Nanosight to study the size of nanogels used in developing drug delivery vehicles

Members of the Lyon Group at Georgia Institute of Technology discuss results from the NanoSight LM-20 system. (main user, Michael Smith, is in the striped shirt)
Members of the Lyon Group at Georgia Institute of Technology discuss results from the NanoSight LM-20 system. (main user, Michael Smith, is in the striped shirt)

Abstract:
The School of Chemistry & Biochemistry at Georgia Institute of Technology has chosen the NanoSight LM-20 system to help in the characterisation of dimensional changes of nanogels used in the development of drug delivery vehicles for macromolecular therapeutics.

Georgia Institute of Technology selects Nanosight to study the size of nanogels used in developing drug delivery vehicles

Salisbury, UK | Posted on January 13th, 2010

The GIT research group of Professor Andrew Lyon works on the development and implementation of new, environmentally responsive (or "smart") materials for photonic materials, bioanalysis, and biomimetics. The approach the group is taking is to design hydrogel nanoparticles that undergo large changes in their chemical, mechanical, optical, or electrical makeup in response to a chemical stimulus, biomolecular interaction, or electromagnetic field; such materials can be viewed as amplifiers or sensitisers of the environmental event. As a result of their environmental sensitivity, nanogels have potential in a number of applications.

Principal user is PhD candidate, Michael Smith. He has been very impressed with the instrument. "The NanoSight has been an enabling tool for us in the characterisation of dilute nanogel samples, where DLS fails to produce reliable correlation data. For instance, in our recent investigations of degradable nanogels, we used the NanoSight for sizing and number density estimation throughout the erosion reaction. In these studies, sample concentrations were typically very low at later stages of the degradation reaction (due to particle loss). Similarly, the NanoSight is effective at measuring the fractionated samples from Asymmetrical flow field-flow fractionation (where samples are greatly diluted following separation)."

Smith continued, "the LM-20 has also been used to characterize a variety of other particle types in the group in conjunction with other light scattering and microscopy methods, to provide topological information for various nanoparticles."

NanoSight's approach, known as Nanoparticle Tracking Analysis (NTA), has been shown to be ideally suited to both research and process control use. The system is an extremely powerful nanoscale research and development tool for looking a broad range of particle types and concentrations.

To learn more about nanoparticle characterisation using NTA, please visit the company's website (www.nanosight.com) and register for the latest issue of NanoTrail, the company's electronic newsletter.

####

About NanoSight
NanoSight Ltd, of Salisbury, UK, is the world leading provider of instruments for the optical detection and real time analysis of sub-micron particles. The Company supplies unique instruments for nanoparticle analysis in the sub-micron region that go far beyond existing light scattering techniques in the characterisation of polydispersed systems. NanoSight delivers direct visualisation of individual nanoscale particles in suspension from which independent quantitative estimation of particle size, size distribution and concentration are immediately obtained. In viral titre assessment, NanoSight produces more accurate concentration results than plaque assay, and delivers them within minutes, validating the results with a unique real-time image. Founded in 2004, the company currently has more than 200 systems in service worldwide, having begun commercial sales in 2006.

The Company has a growing base of users worldwide, including BASF, BP GlaxoSmithKline, Novartis, 3M Corp, Roche, Solvay & Unilever and many universities.

For more information, please click here

Contacts:
NanoSight Limited
Minton Park
London Road
Amesbury SP4 7RT
T +44 (0) 1980 676060
F +44 (0) 1980 624703


NetDyaLog Limited
39 de Bohun Court
Saffron Walden
Essex CB10 2BA
T +44 (0) 1799 521881
M +44 (0) 7843 012997

Copyright © NanoSight

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Self-assembling biomaterial forms nanostructure templates for human tissue formation April 27th, 2015

International research team discovers new mechanism behind malaria progression: Findings provide a new avenue for research in malaria treatment April 27th, 2015

More is less in novel electronic material: Adding electrons actually shrinks the system April 27th, 2015

Sensor Designed in Iran Able to Remove Formaldehyde Gas from Environment April 27th, 2015

Nanomedicine

Self-assembling biomaterial forms nanostructure templates for human tissue formation April 27th, 2015

International research team discovers new mechanism behind malaria progression: Findings provide a new avenue for research in malaria treatment April 27th, 2015

Scientists join forces to reveal the mass and shape of single molecules April 27th, 2015

Northwestern scientists develop first liquid nanolaser: Technology could lead to new way of doing 'lab on a chip' medical diagnostics April 25th, 2015

Announcements

Scientists join forces to reveal the mass and shape of single molecules April 27th, 2015

The 16th Trends in Nanotechnology International Conference (TNT 2015) unveils 25 Keynote Speakers: Call for abstracts open April 27th, 2015

Graphenea celebrates fifth anniversary April 27th, 2015

Sensor Designed in Iran Able to Remove Formaldehyde Gas from Environment April 27th, 2015

Tools

International research team discovers new mechanism behind malaria progression: Findings provide a new avenue for research in malaria treatment April 27th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

ORNL reports method that takes quantum sensing to new level April 23rd, 2015

Richards-Kortum elected to American Academy of Arts and Sciences: April 22nd, 2015

Environment

Nanoparticles Used to Improve Mechanical, Thermal Properties of Cellulose Fibers April 23rd, 2015

Young NTU Singapore spin-off clinches S$4.3 million joint venture with Chinese commercial giant March 23rd, 2015

New processing technology converts packing peanuts to battery components March 22nd, 2015

EU Funded PCATDES Project has completed its half-period with success March 19th, 2015

Nanobiotechnology

Self-assembling biomaterial forms nanostructure templates for human tissue formation April 27th, 2015

Scientists join forces to reveal the mass and shape of single molecules April 27th, 2015

A silver lining: UCSB researchers cradle silver nanoclusters inside synthetic DNA to create a programmed, tunable fluorescent array April 23rd, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

New-Contracts/Sales/Customers

Oxford Instruments commissions high field outsert magnet system for the National High Magnetic Field Laboratory 32 Tesla magnet program April 17th, 2015

JPK reports on the use of the NanoWizardŽ 3 AFM system at the Hebrew University of Jerusalem April 14th, 2015

Deben reports on the research of Dr Sunita Ho from UCSF using a CCT500 tensile stage to study the behaviour of dental materials April 14th, 2015

UK National Graphene Institute Selects Bruker as Official Partner: World-Leading Graphene Research Facility Purchases Multiple Bruker AFMs April 7th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project