Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > NC State Research to Determine Where Nanomaterials Go in the Body

Abstract:
Tiny, engineered nanomaterials can already be found in many consumer products, and have been hailed as having widespread future uses in areas ranging from medicine to industrial processes. However, little is known about what happens if these nanomaterials get into your body - where do they go? NC State researchers are working to answer that question under a grant from the National Institutes of Health (NIH).

NC State Research to Determine Where Nanomaterials Go in the Body

Raleigh, NC | Posted on November 2nd, 2009

"There has been a great deal of research into the use of manufactured carbon nanomaterials in various products, but there are still a lot of questions about how these materials will interact with biological systems," says Dr. Nancy Monteiro-Riviere, a professor of investigative dermatology and toxicology at the Center for Chemical Toxicology Research and Pharmacokinetics at NC State and lead investigator of the study. "There is a crucial need to understand how these manufactured carbon nanomaterials will act once they are in the body - particularly where environmental or occupational exposure can occur."

The two-year research project, which is being funded by NIH at approximately $658,000, has several specific goals. First, the researchers will determine how and whether the size and surface charge of four fullerenes - or specifically shaped carbon nanoparticles - effects how the fullerenes interact with the body. "Our hypothesis is that the size and charge of these fullerenes will dictate how the nanoparticles are absorbed by the body, how they are distributed within the body, how the body metabolizes the nanoparticles and - ultimately - how and whether the body can eliminate the nanoparticles," says Monteiro-Riviere.

A second goal is to determine how fullerene size and surface charge affect the distribution of the nanoparticles in the body's organs and plasma, when the fullerenes are injected intravenously. This component of the study will be performed in animal models that are well understood, and where the findings can then be extrapolated to humans. Researchers will also identify any adverse health effects resulting from acute exposure to the nanomaterials.

Finally, the researchers will assess how the body absorbs fullerenes when exposed to the nanomaterials orally or through abraded skin - two routes of exposure that are particularly relevant to real-world scenarios, such as exposure in the workplace.

"The work being done in this project will not only improve our understanding of how nanomaterials behave in the body, but will also help us identify in vitro assays, which can be performed in a laboratory, that predict how the nanomaterials will behave in the body," says Monteiro-Riviere.

NC State's research team working on the project includes Drs. Nancy Monteiro-Riviere, Jim Riviere, Burroughs Wellcome Fund Distinguished Professor of Pharmacology and director of the Center for Chemical Toxicology Research and Pharmacokinetics, Xin Xia, research assistant professor of pharmacology, and Keith Linder, assistant professor of pathology.

####

About North Carolina State University
With more than 31,000 students and nearly 8,000 faculty and staff, North Carolina State University is a comprehensive university known for its leadership in education and research, and globally recognized for its science, technology, engineering and mathematics leadership.

NC State students, faculty and staff are focused. As one of the leading land-grant institutions in the nation, NC State is committed to playing an active and vital role in improving the quality of life for the citizens of North Carolina, the nation and the world.

For more information, please click here

Contacts:
Matt Shipman
News Services
919.515.6386

Dr. Nancy Monteiro-Riviere
919.513.6426

Copyright © North Carolina State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists refine formula for nanotube types: Rice University theorists determine factors that give tubes their chiral angles September 17th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Toward making lithium-sulfur batteries a commercial reality for a bigger energy punch September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Preparing for Nano

Durnham University's DEEPEN project comes to a close September 26th, 2012

Technical Seminar at ANFoS 2012 August 22nd, 2012

Nanotechnology shows we can innovate without economic growth April 12th, 2012

Thailand to host NanoThailand 2012 December 18th, 2011

Nanomedicine

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Nanoscience makes your wine better September 17th, 2014

Treatment of Cell Infection by Nanotechnology September 15th, 2014

Announcements

New NPZ100-403 Piezo Stage from nPoint Inc. September 17th, 2014

Scientists refine formula for nanotube types: Rice University theorists determine factors that give tubes their chiral angles September 17th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Toward making lithium-sulfur batteries a commercial reality for a bigger energy punch September 17th, 2014

Personal Care

Sunblock poses potential hazard to sea life August 20th, 2014

AQUANOVA receives Technology Leadership Award 2014 FROST & SULLIVAN honors NovaSOL® Technology again August 12th, 2014

Nanotechnology used in sunscreens: a Mexican achievement May 14th, 2014

Production of Nanocapsule from Sea-Buckthorn Extract in Iran May 3rd, 2014

Safety-Nanoparticles/Risk management

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Sunblock poses potential hazard to sea life August 20th, 2014

Analytical solutions from Malvern Instruments support University of Wisconsin-Milwaukee researchers in understanding environmental effects of nanomaterials July 30th, 2014

NNCO Announces an Interactive Webinar: Progress Review on the Coordinated Implementation of the National Nanotechnology Initiative 2011 Environmental, Health, and Safety Research Strategy July 23rd, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Effective Nanotechnology Innovations to Receive Mustafa Prize September 16th, 2014

‘Small’ transformation yields big changes September 16th, 2014

Elusive Quantum Transformations Found Near Absolute Zero: Brookhaven Lab and Stony Brook University researchers measured the quantum fluctuations behind a novel magnetic material's ultra-cold ferromagnetic phase transition September 15th, 2014

Rice rolls 'neat' nanotube fibers: Rice University researchers' acid-free approach leads to strong conductive carbon threads September 15th, 2014

Nanobiotechnology

Recruiting bacteria to be technology innovation partners: September 17th, 2014

NanoStruck has a High Recovery Rate on Mine Tailings: retrieval of up to 96% of Gold, 88% of Silver and 86% of Palladium September 12th, 2014

Boosting armor for nuclear-waste eating microbes September 12th, 2014

Researchers Create World’s Largest DNA Origami September 11th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE