Home > Press > Fighting Against Bacteria
Abstract:
New nano-material kills antibiotic-resistant bacteria
Doctors are not well armed in the fight against antibiotic-resitant bacteria. It is very difficult - or, in the worst case, impossible - to fight such infections. A team of researchers in Münster has now developed a unique nano-material that kills antibiotic-resitant bacteria.
Researchers from Münster University and CeNTech (Center for NanoTechnology) were involved in the work, with Prof. Luisa De Cola leading the chemists and Prof. Berenike Maier heading the biologists. "Our results are a premiere. For the first time we have shown that it is possible to equip nano-particles with the following three functions: the particles adhere specifically to bacteria, mark them and then kill them off," says Dr. Cristian Strassert from the Physical Institute at WWU, who led the work on the study.
The starting material used by the researchers is so-called zeolite-L-nano-crystals. In a simple, inexpensive process these nano-particles are provided with a component which enables the particles to adhere to the surface of the bacteria. In addition, the particles are equipped with a colourant which glows green under a fluorescence microscope and makes the bacteria visible.
The effectiveness of the nano-particles is based on the "photodynamic therapy" method, whereby exposure to light sets off a reaction which kills the bacteria cells. The researchers also tack a third material on to the nano-crystals which is activated by red light and produces certain aggressive oxygen molecules. These oxygen molecules - "singlet oxygen" - start a chain reaction which destroys the bacteria cell.
The new nano-particles have hitherto adhered, through electrostatic interplay, to types of bacteria with certain surface properties ("gram-negativ"). The researchers are now working on making binding to other types of bacteria possible and increasing the binding specifity. In future the method could then be used to target certain bacteria in localised illnesses.
"Moreover," says Strassert, "we are looking at whether the method could be used not only to fight antibiotic-resitant bacteria, but also in the treatment of skin cancer." To this end the scientists want to get the nano-particles to bind specifically to cancer cells. "If that succeeds it would be conceivable for the nano-particles to be applied to the skin in future in a cream," says Strassert, describing his vision. "Through exposure to light the particles could then be activated and the cancer cells destroyed."
####
About Westfälische Wilhelms-Universität Münster
The research profile of the WWU Münster is marked by a considerable number of research focal points of proven excellence – in the humanities (including the Theological Faculties), law, business administration, natural sciences, mathematics and medicine. For example the Leibniz Prize, also known as the "German Nobel Prize", has been awarded to WWU Münster no fewer than four times since 2003. The award-winners are Prof. Hubert Wolf (theology), Prof. Barbara Stollberg-Rilinger (history), Prof. Klaus Mezger (geochemistry) and Prof. Wolfgang Lück (mathematics).
For more information, please click here
Contacts:
Schlossplatz 2
D-48149 Münster
Tel: +49(0)251/83-0
Fax: +49(0)251/83-3 20 90
Copyright © Westfälische Wilhelms-Universität Münster
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related News Press |
News and information
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Products
Spectradyne Partners with Particle Technology Labs for Measurement Services December 6th, 2018
Mode-Changing MEMS Accelerometer from STMicroelectronics Combines High Measurement Resolution and Ultra-Low Power for Industrial Applications November 7th, 2018
Fat-Repellent Nanolayers Can Make Oven Cleaning Easier October 17th, 2018
Aculon, Inc. Enters into Strategic Partnership Agreement with Henkel Corporation to Supply Key Mobile Device Manufacturers with NanoProof® PCB Waterproof Technology October 17th, 2018
Possible Futures
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
With VECSELs towards the quantum internet Fraunhofer: IAF achieves record output power with VECSEL for quantum frequency converters April 5th, 2024
Nanomedicine
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Announcements
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanobiotechnology
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||