Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > New biosensor can detect bacteria instantaneously

Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.
Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.

Abstract:
A research group from the Rovira i Virgili University (URV) in Tarragona has developed a biosensor that can immediately detect very low levels of Salmonella typhi, the bacteria that causes typhoid fever. The technique uses carbon nanotubes and synthetic DNA fragments that activate an electric signal when they link up with the pathogen.

New biosensor can detect bacteria instantaneously

Spain | Posted on September 11th, 2009

"We have developed a new biosensor that can detect extremely low concentrations of bacteria immediately, easily and reliably", F. Xavier Rius, lead author of the study and a professor in the Chemometrics, Qualimetrics and Nanosensors research group in the Analytical Chemistry and Organic Chemistry Department of the URV, tells SINC.

Rius' team, jointly led by Jordi Riu, has come up with a technique that can detect extremely low levels of the bacteria Salmonella typhi, which causes typhoid fever. This new biosensor functions using a method, described this month in the scientific journal Angewandte Chemie International Edition, which involves carbon nanotubes with inbuilt aptamers providing electrochemical readings.

The aptamers are small fragments of artificial DNA or RNA designed to attach themselves specifically to a particular molecule, cell or micro organism, in this case Salmonella. If the bacteria are not present, the aptamers remain on the walls of the carbon nanotubes. However, if they detect bacteria, they become activated and stick to it, and the carbon nanotubes generate an electric signal that is picked up by a simple potentiometer connected to the biosensor.

"The presence of the bacteria sparks a change in the interaction between the aptamers and the nanotubes, which takes place in a few seconds and creates an increase in the voltage of the electrode", says Rius.

Traditional methods for identifying and measuring micro organisms require one or two days' analysis. "This technique means small quantities of micro organisms can be detected simply and practically in real time, just the same as measuring the pH of water", adds the researcher.

This study is part of the international research being carried out to find the most effective and fast ways of detecting all kinds of pathogens. The new biosensor makes it possible to identify a single cell of Salmonella in a five-millilitre sample and can successfully make quantitative measurements of up to 1,000 bacteria per millilitre.

References:

Gustavo A. Zelada-Guillén, Jordi Riu, Ali Düzgün, F. Xavier Rius. "Immediate Detection of Living Bacteria at Ultralow Concentrations Using a Carbon Nanotube Based Potentiometric Aptasensor". Angewandte Chemie International Edition, Septiembre de 2009. DOI: 10.1002/anie.200902090.

####

About FECYT - Spanish Foundation for Science and Technology
The Spanish Science and Technology Foundation (FECYT), dependent organisation on Ministry of Science and Innovation, was born in 2001 as a tool of the national system of knowledge generation and technological transfer. The Foundation operates as a non-profit private association and with functional autonomy, with the goal of rendering a continuous and flexible service to the Spanish system of science-technology-enterprise.

For more information, please click here

Contacts:
SINC

34-914-251-820

Copyright © Eurekalert

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Synthetic Biology

Living computers: RNA circuits transform cells into nanodevices July 27th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Fast, efficient sperm tails inspire nanobiotechnology December 5th, 2016

Measuring forces in the DNA molecule: First direct measurements of base-pair bonding strength September 13th, 2016

Possible Futures

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Fewer defects from a 2-D approach August 15th, 2017

Nanotubes/Buckyballs/Fullerenes/Nanorods

Regulation of two-dimensional nanomaterials: New driving force for lithium-ion batteries July 26th, 2017

Killing cancer in the heat of the moment: A new method efficiently transfers genes into cells, then activates them with light. This could lead to gene therapies for cancers July 9th, 2017

Tests show no nanotubes released during utilisation of nanoaugmented materials June 9th, 2017

Ag/ZnO-Nanorods Schottky diodes based UV-PDs are fabricated and tested May 26th, 2017

Sensors

Sensing technology takes a quantum leap with RIT photonics research: Office of Naval Research funds levitated optomechanics project August 10th, 2017

Giant enhancement of electromagnetic waves revealed within small dielectric particles: Scientists have done for the first time direct measurements of giant electromagnetic fields July 8th, 2017

Bosch announces high-performance MEMS acceleration sensors for wearables June 27th, 2017

Leti’s Autonomous-Vehicle System Embedded in Infineon’s AURIX Platform: Leti’s Low-Power, Multi-Sensor System that Transforms Distance Data into Clear Information About the Driving Environment Will Be Demonstrated at ITS Meeting in Strasbourg, June 19-22 June 20th, 2017

Announcements

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Homeland Security

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Nanosensors on the alert for terrorist threats: Scientists interested in the prospects of gas sensors based on binary metal oxide nanocomposites November 5th, 2016

Nanobionic spinach plants can detect explosives: After sensing dangerous chemicals, the carbon-nanotube-enhanced plants send an alert November 2nd, 2016

Notre Dame researchers find transition point in semiconductor nanomaterials September 6th, 2016

Military

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

2-faced 2-D material is a first at Rice: Rice University materials scientists create flat sandwich of sulfur, molybdenum and selenium August 14th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Sensing technology takes a quantum leap with RIT photonics research: Office of Naval Research funds levitated optomechanics project August 10th, 2017

Nanobiotechnology

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

JPK reports on how the University of Glasgow is using their NanoWizard® AFM and CellHesion module to study how cells interact with their surroundings August 2nd, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project