Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > New biosensor can detect bacteria instantaneously

Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.
Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.

Abstract:
A research group from the Rovira i Virgili University (URV) in Tarragona has developed a biosensor that can immediately detect very low levels of Salmonella typhi, the bacteria that causes typhoid fever. The technique uses carbon nanotubes and synthetic DNA fragments that activate an electric signal when they link up with the pathogen.

New biosensor can detect bacteria instantaneously

Spain | Posted on September 11th, 2009

"We have developed a new biosensor that can detect extremely low concentrations of bacteria immediately, easily and reliably", F. Xavier Rius, lead author of the study and a professor in the Chemometrics, Qualimetrics and Nanosensors research group in the Analytical Chemistry and Organic Chemistry Department of the URV, tells SINC.

Rius' team, jointly led by Jordi Riu, has come up with a technique that can detect extremely low levels of the bacteria Salmonella typhi, which causes typhoid fever. This new biosensor functions using a method, described this month in the scientific journal Angewandte Chemie International Edition, which involves carbon nanotubes with inbuilt aptamers providing electrochemical readings.

The aptamers are small fragments of artificial DNA or RNA designed to attach themselves specifically to a particular molecule, cell or micro organism, in this case Salmonella. If the bacteria are not present, the aptamers remain on the walls of the carbon nanotubes. However, if they detect bacteria, they become activated and stick to it, and the carbon nanotubes generate an electric signal that is picked up by a simple potentiometer connected to the biosensor.

"The presence of the bacteria sparks a change in the interaction between the aptamers and the nanotubes, which takes place in a few seconds and creates an increase in the voltage of the electrode", says Rius.

Traditional methods for identifying and measuring micro organisms require one or two days' analysis. "This technique means small quantities of micro organisms can be detected simply and practically in real time, just the same as measuring the pH of water", adds the researcher.

This study is part of the international research being carried out to find the most effective and fast ways of detecting all kinds of pathogens. The new biosensor makes it possible to identify a single cell of Salmonella in a five-millilitre sample and can successfully make quantitative measurements of up to 1,000 bacteria per millilitre.

References:

Gustavo A. Zelada-Guillén, Jordi Riu, Ali Düzgün, F. Xavier Rius. "Immediate Detection of Living Bacteria at Ultralow Concentrations Using a Carbon Nanotube Based Potentiometric Aptasensor". Angewandte Chemie International Edition, Septiembre de 2009. DOI: 10.1002/anie.200902090.

####

About FECYT - Spanish Foundation for Science and Technology
The Spanish Science and Technology Foundation (FECYT), dependent organisation on Ministry of Science and Innovation, was born in 2001 as a tool of the national system of knowledge generation and technological transfer. The Foundation operates as a non-profit private association and with functional autonomy, with the goal of rendering a continuous and flexible service to the Spanish system of science-technology-enterprise.

For more information, please click here

Contacts:
SINC

34-914-251-820

Copyright © Eurekalert

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

Synthetic Biology

Researchers of the University of Tartu create a centre for developing designer cells with new functions April 8th, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

New tool could help reshape the limits of synthetic biology: The 'telomerator' reshapes synthetic yeast chromosome into more flexible, realistic form, redefining what geneticists can build November 3rd, 2014

Tiny carbon nanotube pores make big impact October 29th, 2014

Possible Futures

Printing Silicon on Paper, with Lasers April 21st, 2015

A glass fiber that brings light to a standstill: By coupling photons to atoms, light in a glass fiber can be slowed down to the speed of an express train; for a short while it can even be brought to a complete stop April 9th, 2015

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Nanotechnology Enabled Drug Delivery to Influence Future Diagnosis and Treatments of Diseases March 21st, 2015

Nanotubes/Buckyballs/Fullerenes

SouthWest NanoTechnologies CEO Dave Arthur to Speak at NanoBCA DC Roundtable on May 19 in Washington DC April 20th, 2015

How to maximize the superconducting critical temperature in a molecular superconductor: International team led by Tohoku University opens new route for discovering high Tc superconductors April 19th, 2015

Nanotubes with two walls have singular qualities: Rice University lab calculates unique electronic qualities of double-walled carbon nanotubes April 16th, 2015

MIT sensor detects spoiled meat: Tiny device could be incorporated into 'smart packaging' to improve food safety April 15th, 2015

Sensors

ORNL reports method that takes quantum sensing to new level April 23rd, 2015

New class of 3D-printed aerogels improve energy storage April 22nd, 2015

‘Oxford Instruments Young Nanoscientist India Award 2015’ to Prof. Arindam Ghosh April 20th, 2015

Optical resonance-based biosensors designed for medical applications April 18th, 2015

Announcements

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

Homeland Security

UCLA nanoscientists are first to model atomic structures of three bacterial nanomachines: Cryo electron microscope enables scientists to explore the frontiers of targeted antibiotics April 21st, 2015

Optics, nanotechnology combined to create low-cost sensor for gases April 3rd, 2015

The Universitat Politècnica de València is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th, 2015

Detecting chemical weapons with a color-changing film January 28th, 2015

Military

Electron spin brings order to high entropy alloys April 23rd, 2015

Engineer improves rechargeable batteries with MoS2 nano 'sandwich' April 18th, 2015

Cobalt film a clean-fuel find: Rice University discovery is efficient, robust at drawing hydrogen and oxygen from water April 15th, 2015

MIT sensor detects spoiled meat: Tiny device could be incorporated into 'smart packaging' to improve food safety April 15th, 2015

Nanobiotechnology

A silver lining: UCSB researchers cradle silver nanoclusters inside synthetic DNA to create a programmed, tunable fluorescent array April 23rd, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

UCLA nanoscientists are first to model atomic structures of three bacterial nanomachines: Cryo electron microscope enables scientists to explore the frontiers of targeted antibiotics April 21st, 2015

Rafts on the cell membrane: Researchers from TU Wien (Vienna) shed light on a big secret of cell membranes: The 'lipid rafts', which have been believed to move within the cell membrane, do not really exist April 21st, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project