Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > New biosensor can detect bacteria instantaneously

Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.
Within the system with carbon nanotubes, the aptamers (red) bind to the bacteria (green), which activates a measurable electrical signal that reveals the presence of the pathogen.

Abstract:
A research group from the Rovira i Virgili University (URV) in Tarragona has developed a biosensor that can immediately detect very low levels of Salmonella typhi, the bacteria that causes typhoid fever. The technique uses carbon nanotubes and synthetic DNA fragments that activate an electric signal when they link up with the pathogen.

New biosensor can detect bacteria instantaneously

Spain | Posted on September 11th, 2009

"We have developed a new biosensor that can detect extremely low concentrations of bacteria immediately, easily and reliably", F. Xavier Rius, lead author of the study and a professor in the Chemometrics, Qualimetrics and Nanosensors research group in the Analytical Chemistry and Organic Chemistry Department of the URV, tells SINC.

Rius' team, jointly led by Jordi Riu, has come up with a technique that can detect extremely low levels of the bacteria Salmonella typhi, which causes typhoid fever. This new biosensor functions using a method, described this month in the scientific journal Angewandte Chemie International Edition, which involves carbon nanotubes with inbuilt aptamers providing electrochemical readings.

The aptamers are small fragments of artificial DNA or RNA designed to attach themselves specifically to a particular molecule, cell or micro organism, in this case Salmonella. If the bacteria are not present, the aptamers remain on the walls of the carbon nanotubes. However, if they detect bacteria, they become activated and stick to it, and the carbon nanotubes generate an electric signal that is picked up by a simple potentiometer connected to the biosensor.

"The presence of the bacteria sparks a change in the interaction between the aptamers and the nanotubes, which takes place in a few seconds and creates an increase in the voltage of the electrode", says Rius.

Traditional methods for identifying and measuring micro organisms require one or two days' analysis. "This technique means small quantities of micro organisms can be detected simply and practically in real time, just the same as measuring the pH of water", adds the researcher.

This study is part of the international research being carried out to find the most effective and fast ways of detecting all kinds of pathogens. The new biosensor makes it possible to identify a single cell of Salmonella in a five-millilitre sample and can successfully make quantitative measurements of up to 1,000 bacteria per millilitre.

References:

Gustavo A. Zelada-Guillén, Jordi Riu, Ali Düzgün, F. Xavier Rius. "Immediate Detection of Living Bacteria at Ultralow Concentrations Using a Carbon Nanotube Based Potentiometric Aptasensor". Angewandte Chemie International Edition, Septiembre de 2009. DOI: 10.1002/anie.200902090.

####

About FECYT - Spanish Foundation for Science and Technology
The Spanish Science and Technology Foundation (FECYT), dependent organisation on Ministry of Science and Innovation, was born in 2001 as a tool of the national system of knowledge generation and technological transfer. The Foundation operates as a non-profit private association and with functional autonomy, with the goal of rendering a continuous and flexible service to the Spanish system of science-technology-enterprise.

For more information, please click here

Contacts:
SINC

34-914-251-820

Copyright © Eurekalert

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

'Lasers rewired': Scientists find a new way to make nanowire lasers: Berkeley Lab, UC Berkeley scientists adapt next-gen solar cell materials for a different purpose February 12th, 2016

Breaking cell barriers with retractable protein nanoneedles: Adapting a bacterial structure, Wyss Institute researchers develop protein actuators that can mechanically puncture cells February 12th, 2016

Replacement of Toxic Antibacterial Agents Possible by Biocompatible Polymeric Nanocomposites February 12th, 2016

Properties of Polymeric Nanofibers Optimized to Treat Damaged Body Tissues February 12th, 2016

Synthetic Biology

Chemical cages: New technique advances synthetic biology February 10th, 2016

DNA 'building blocks' pave the way for improved drug delivery January 12th, 2016

Imitating synapses of the human brain could lead to smarter electronics November 15th, 2015

Newly discovered 'design rule' brings nature-inspired nanostructures one step closer: Computer sims and microscopy research at Berkeley Lab yield first atomic-resolution structure of a peptoid nanosheet October 8th, 2015

Possible Futures

'Lasers rewired': Scientists find a new way to make nanowire lasers: Berkeley Lab, UC Berkeley scientists adapt next-gen solar cell materials for a different purpose February 12th, 2016

Breaking cell barriers with retractable protein nanoneedles: Adapting a bacterial structure, Wyss Institute researchers develop protein actuators that can mechanically puncture cells February 12th, 2016

Replacement of Toxic Antibacterial Agents Possible by Biocompatible Polymeric Nanocomposites February 12th, 2016

Properties of Polymeric Nanofibers Optimized to Treat Damaged Body Tissues February 12th, 2016

Nanotubes/Buckyballs/Fullerenes

Superconductivity: Footballs with no resistance - Indications of light-induced lossless electricity transmission in fullerenes contribute to the search for superconducting materials for practical applications February 9th, 2016

The iron stepping stones to better wearable tech without semiconductors February 8th, 2016

Nano-coating makes coaxial cables lighter: Rice University scientists replace metal with carbon nanotubes for aerospace use January 28th, 2016

Scientists provide new guideline for synthesis of fullerene electron acceptors January 28th, 2016

Sensors

Scientists have put a high precision blood assay into a simple test strip: Researchers have developed a new biosensor test system based on magnetic nanoparticles February 3rd, 2016

Nanosheet growth technique could revolutionize nanomaterial production February 1st, 2016

New record in nanoelectronics at ultralow temperatures January 28th, 2016

NBC LEARN DEBUTS SIX-PART VIDEO SERIES, “NANOTECHNOLOGY: SUPER SMALL SCIENCE” Produced by NBC Learn in partnership with the National Science Foundation, and narrated by NBC News/MSNBC’s Kate Snow, series highlights leading research in nanotechnology January 25th, 2016

Announcements

Graphene leans on glass to advance electronics: Scientists' use of common glass to optimize graphene's electronic properties could improve technologies from flat screens to solar cells February 12th, 2016

Breaking cell barriers with retractable protein nanoneedles: Adapting a bacterial structure, Wyss Institute researchers develop protein actuators that can mechanically puncture cells February 12th, 2016

Replacement of Toxic Antibacterial Agents Possible by Biocompatible Polymeric Nanocomposites February 12th, 2016

Properties of Polymeric Nanofibers Optimized to Treat Damaged Body Tissues February 12th, 2016

Homeland Security

Detecting and identifying explosives with single test December 10th, 2015

Columbia engineers build biologically powered chip: System combines biological ion channels with solid-state transistors to create a new kind of electronics December 7th, 2015

Nanoparticle delivery maximizes drug defense against bioterrorism agent: UCLA team develops method for improving drug’s efficacy while reducing side effects November 6th, 2015

Toward clearer, cheaper imaging of ultrafast phenomena: A new, all-optical method for compressing narrow electron pulses to a billionth of a billionth of a second could improve real-time movies of chemical reactions and other ultrafast processes October 14th, 2015

Military

Scientists guide gold nanoparticles to form 'diamond' superlattices: DNA scaffolds cage and coax nanoparticles into position to form crystalline arrangements that mimic the atomic structure of diamond February 4th, 2016

Researchers develop completely new kind of polymer: Hybrid polymers could lead to new concepts in self-repairing materials, drug delivery and artificial muscles January 30th, 2016

Nano-coating makes coaxial cables lighter: Rice University scientists replace metal with carbon nanotubes for aerospace use January 28th, 2016

Scientists build a neural network using plastic memristors: A group of Russian and Italian scientists have created a neural network based on polymeric memristors -- devices that can potentially be used to build fundamentally new computers January 28th, 2016

Nanobiotechnology

Breaking cell barriers with retractable protein nanoneedles: Adapting a bacterial structure, Wyss Institute researchers develop protein actuators that can mechanically puncture cells February 12th, 2016

Replacement of Toxic Antibacterial Agents Possible by Biocompatible Polymeric Nanocomposites February 12th, 2016

Properties of Polymeric Nanofibers Optimized to Treat Damaged Body Tissues February 12th, 2016

SLAC X-ray laser turns crystal imperfections into better images of important biomolecules: New method could remove major obstacles to studying structures of complex biological machines February 11th, 2016

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic