Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Virginia Tech's proposed next generation nano-CT system will enhance nano-scale research

Virginia Tech's advanced multi-scale computed tomography facilities will soon include a Xradia Nano-CT system, and already has a Xradia Micro-CT system, and a Scanco micro-CT system, covering a wide range of image resolutions and sample sizes over six orders of magnitude. The instrumentation is shown on the bottom, and the resulting images are above.

Credit: Ge Wang, Virginia Tech
Virginia Tech's advanced multi-scale computed tomography facilities will soon include a Xradia Nano-CT system, and already has a Xradia Micro-CT system, and a Scanco micro-CT system, covering a wide range of image resolutions and sample sizes over six orders of magnitude. The instrumentation is shown on the bottom, and the resulting images are above. Credit: Ge Wang, Virginia Tech

Abstract:
In 1991, Ge Wang produced the first paper on spiral cone-beam computed tomography (CT), now an imaging technique used in the mainstream of the medical CT field. Today, Wang, known as a pioneer in this field, and his colleagues have been awarded more than $1.3 million from the National Science Foundation (NSF) to develop the next-generation nano-CT imaging system, which promises to greatly reduce the required dose of radiation. Virginia Tech and Xradia, a leading nano-CT company, are also collaborating on the project with a cost-sharing investment of close to $800,000.

Virginia Tech's proposed next generation nano-CT system will enhance nano-scale research

Blacksburg, VA | Posted on September 3rd, 2009

CT is an imaging method that shows objects by sections or sectioning, through the use of x-ray waves and computer processing.

"X-ray nano-CT is a cutting edge imaging tool," Wang said, "but a long-standing barrier to realizing its full potential is its inability to precisely reconstruct an interior region of interest within a larger object from purely local projections."

Wang, the Samuel Reynolds Pritchard Professor of Engineering at Virginia Tech, has a scholarly record of achievements in the imaging world. More than 1000 scientific citations are attributed to his group's pioneering efforts. In 2002, for example, he and his research group pioneered another highly sensitive imaging procedure called bioluminescence tomography (BLT). One application of the in vivo molecular imaging technology became the identification of tumors in live animals.

As an additional example, in 2007 he and his collaborators, Yangbo Ye of the University of Iowa and Hengyong Yu, who is the associate director of Wang's CT lab, patented a novel x-ray imaging method called "interior tomography".

Interior tomography, Wang said, was "a first step" towards overcoming the long-standing barrier to realizing the full potential of x-ray nano-CT. Despite the ability of this cutting-edge imaging tool as a non-destructive, non-invasive recorder of information, it cannot "precisely reconstruct an interior region of interest within a large object from purely local projections," Wang said. And, when used in medicine, a patient is subjected to "a radiation dose that must be increased dramatically to obtain improved resolutions."

Wang suggested to the NSF that the combination of X-ray nano-CT and interior tomography will provide "a versatile nano-imaging tool that can visualize fine features within a larger object, and use a much lower radiation dose and in much less time." This new work is the foundation of the NSF project.

Working with Wang on this NSF grant are Chris Wyatt, associate professor of electrical and computer engineering, Linbing Wang, associate professor of civil and environmental engineering, and Yu, all at Virginia Tech. Also, David Carroll, associate professor of physics at Wake Forest University, is a member of the team. On the industrial side, the key collaborators are Steve Wang, S. H. Lau and Wenbing Yun.

Together, they believe they can construct this next generation of a nano-CT imaging system that will provide images that will reveal deeply imbedded details, including subcellular features. And, they believe they can handle a sample that is ten times larger than what is currently available, and at much reduced radiation dose," Wang explained.

Wang, director of the Virginia Tech-Wake Forest University School of Biomedical Engineering Sciences' biomedical imaging division, www.imaging.sbes.vt.edu is also the founding editor-in-chief of the International Journal of Biomedical Imaging. He is the associate editor of the Institute of Electrical and Electronic Engineers (IEEE) Transactions on Medical Imaging and others.

SBES is part of the University's Institute for Critical Technology and Applied Science (ICTAS). www.ictas.vt.edu/index.shtml. ICTAS has already developed a state-of-the-art nanoscale characterization and fabrication laboratory with capabilities on par with the best nanotechnology labs in the world. With his high-end 500 nanometer micro-CT system, newly funded by the National Institutes of Health (NIH), Wang is making efforts to build an advanced multi-scale CT facility in synergistic combination with the existing university resources as shown in the following chart.

"We are realizing our dream to establish the world's most advanced comprehensive multi-scale and multi-parameter CT facility," Wang said. The use of the facility will be available to other universities and industry.

An academic partnership already exists between Virginia Tech and Xradia. Xradia is already in talks with Virginia Tech about commercializing the next generation nano-CT system. www.xradia.com/

####

About Virginia Tech
Virginia Polytechnic Institute and State University, better known as Virginia Tech, is a public land grant polytechnic university in Blacksburg, Virginia, United States.[2] Virginia Tech is well known for its programs in engineering, architecture, science, business and agriculture.

Founded in 1872 as an agricultural and mechanical college, Virginia Tech continues to be one of the few public universities in the United States which maintains a corps of cadets. The Virginia Tech campus is located in the New River Valley in the Valley and Ridge physiographic region of the Appalachian Mountains in southwestern Virginia, a few miles from the Jefferson National Forest in Montgomery County.

From Wikipedia, the free encyclopedia

For more information, please click here

Contacts:
Lynn Nystrom

540-231-4371

Copyright © Eurekalert

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Govt.-Legislation/Regulation/Funding/Policy

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

Stanford team achieves 'holy grail' of battery design: A stable lithium anode - Engineers use carbon nanospheres to protect lithium from the reactive and expansive problems that have restricted its use as an anode July 27th, 2014

Possible Futures

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

Nanomedicine

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Announcements

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Tools

WITec to host the 11th Confocal Raman Imaging Symposium from September 29th - October 1st in Ulm, Germany July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Bruker Announces Acquisition of High-Speed, 3D Super-Resolution Fluorescence Microscopy Company Vutara July 28th, 2014

Malvern Instruments completes acquisition of MicroCal and announces purchase of Archimedes product from Affinity Biosensors July 25th, 2014

Nanobiotechnology

Harris & Harris Group Invests in Unique NYC Biotech Accelerator July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE