Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanoscale origami from DNA - Researchers develop a new toolbox for nano-engineering

DNA molecules as ideal building blocks for nano structures. Image: H. Dietz, TUM Dept. of Physics
DNA molecules as ideal building blocks for nano structures. Image: H. Dietz, TUM Dept. of Physics

Abstract:
Scientists at the Technische Universitaet Muenchen (TUM) and Harvard University have thrown the lid off a new toolbox for building nanoscale structures out of DNA, with complex twisting and curving shapes. In the August 7 issue of the journal Science, they report a series of experiments in which they folded DNA, origami-like, into three-dimensional objects including a beach ball-shaped wireframe capsule just 50 nanometers in diameter.

Nanoscale origami from DNA - Researchers develop a new toolbox for nano-engineering

Germany & Massachusetts | Posted on August 6th, 2009

"Our goal was to find out whether we could program DNA to assemble into shapes that exhibit custom curvature or twist, with features just a few nanometers wide," says biophysicist Hendrik Dietz, a professor at the Technische Universitaet Muenchen. Dietz's collaborators in these experiments were Professor William Shih and Dr. Shawn Douglas of Harvard University. "It worked," he says, "and we can now build a diversity of three-dimensional nanoscale machine parts, such as round gears or curved tubes or capsules. Assembling those parts into bigger, more complex and functional devices should be possible."

As a medium for nanoscale engineering, DNA has the dual advantages of being a smart material - not only tough and flexible but also programmable - and being very well characterized by decades of study. Basic tools that Dietz, Douglas, and Shih employ are programmable self-assembly - directing DNA strands to form custom-shaped bundles of cross-linked double helices - and targeted insertions or deletions of base pairs that can give such bundles a desired twist or curve. Right-handed or left-handed twisting can be specified. They report achieving precise, quantitative control of these shapes, with a radius of curvature as tight as 6 nanometers.

The toolbox they have developed includes a graphical software program that helps to translate specific design concepts into the DNA programming required to realize them. Three-dimensional shapes are produced by "tuning" the number, arrangement, and lengths of helices.

In their current paper, the researchers present a wide variety of nanoscale structures and describe in detail how they designed, formed, and verified them. "Many advanced macroscopic machines require curiously shaped parts in order to function," Dietz says, "and we have the tools to make them. But we currently cannot build something intricate such as an ant's leg or, much smaller, a ten-nanometer-small chemical plant such as a protein enzyme. We expect many benefits if only we could build super-miniaturized devices on the nanoscale using materials that work robustly in the cells of our bodies - biomolecules such as DNA."

Original paper:

Folding DNA into Twisted and Curved Nanoscale Shapes
Hendrik Dietz, Shawn M. Douglas, and William M. Shih,
Science 7 August 2009: Vol. 325. no. 5941, pp. 725 - 730 - DOI: 10.1126/science.1174251

####

About Technische Universitaet Muenchen
Technische Universität München (TUM; sometimes translated as Technical University Munich)[2] is a research university with campuses in Munich, Garching, and Weihenstephan.

TUM is among the highest acclaimed universities in Germany, producing several Nobel Laureates including Gerhard Ertl who in 2007 received the Nobel Prize in Chemistry.

From Wikipedia, the free encyclopedia

For more information, please click here

Contacts:
Prof. Hendrik Dietz
Department of Physics
Technische Universitaet Muenchen
James-Franck-Str. 1, 85748 Garching, Germany
Tel. +49 89 289 12539
Fax: +49 89 289 12523

Copyright © Technische Universitaet Muenchen

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Fonon Announces 3D Metal Sintering Technology: Emerging Additive Nano Powder Manufacturing Technology August 28th, 2014

Ultra-Low Frequency Vibration Isolation Stabilizes Scanning Tunneling Microscopy at UCLA’s Nano-Research Group August 28th, 2014

Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices August 28th, 2014

New technique uses fraction of measurements to efficiently find quantum wave functions August 28th, 2014

Possible Futures

Air Force’s 30-year plan seeks 'strategic agility' August 1st, 2014

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Molecular Machines

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

University of Illinois researchers demonstrate novel, tunable nanoantennas July 14th, 2014

Announcements

Leading European communications companies and research organizations have launched an EU project developing the future 5th Generation cellular mobile networks August 28th, 2014

Ultra-Low Frequency Vibration Isolation Stabilizes Scanning Tunneling Microscopy at UCLA’s Nano-Research Group August 28th, 2014

Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices August 28th, 2014

New technique uses fraction of measurements to efficiently find quantum wave functions August 28th, 2014

Nanobiotechnology

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Сalculations with Nanoscale Smart Particles August 19th, 2014

Interaction between Drug, DNA for Designing Anticancer Drugs Studied in Iran August 17th, 2014

Scientists fold RNA origami from a single strand: RNA origami is a new method for organizing molecules on the nanoscale. Using just a single strand of RNA, this technique can produce many complicated shapes. August 14th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE