Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UCLA’s New Center For NanoBiology Begins Sub-Nanometer Molecular Imaging with FEI Titan Krios Microscope

Abstract:
FEI's automated molecular imaging solution will be used to understand the causes of disease

UCLA’s New Center For NanoBiology Begins Sub-Nanometer Molecular Imaging with FEI Titan Krios Microscope

Hillsboro, OR | Posted on August 6th, 2009

FEI Company (Nasdaq: FEIC), a leading provider of three-dimensional (3D) molecular, cellular and atomic-scale imaging systems, today announced that the University of California at Los Angeles (UCLA) has installed a multi-million dollar Titan Krios™ transmission electron microscope (TEM) from FEI. In an effort to understand the causes of disease, UCLA's Dr. Hong Zhou, director of the newly-established Electron Imaging Center for NanoMachines (EICN), part of the California NanoSystems Institute, has initiated high-resolution molecular imaging studies using the new Titan Krios TEM.

The Titan Krios is specifically designed for 3D molecular imaging applications where samples are imaged at cryogenic temperatures, which preserves the biological samples in their native hydrated state. The microscope's ability to generate images used in the creation of 3D molecular structures with resolutions as small as a few tenths of a nanometer allows scientists to investigate the structure and function of biological nanomachines at the molecular scale.

"We are very pleased to begin the next phase of our partnership with UCLA," said Matthew Harris, FEI's vice president and general manager of the Life Sciences Division. "Dr. Zhou and his colleagues recently achieved breakthrough results in 3D molecular reconstruction with resolution better than four Ångströms using an FEI Tecnai Polara™ TEM. We are confident that Dr. Zhou will continue to push the boundaries of molecular imaging, and we look forward to supporting him with many groundbreaking discoveries using the Titan Krios."

Dr. Zhou adds, "The advanced optics, automation and cryo capabilities of the Titan Krios are absolutely essential for our research in nanobiology and nanomedicine. Developments in these areas will expand opportunities to contribute to major advances in rational drug design and targeted delivery, and ultimately advance us towards biology-inspired nanomachines."

Recent advances have made cryo-electron microscopy (cryo-EM) an important imaging tool for major applications in both medicine and nanobiological research. Researchers can use cryo-EM to visualize a broad range of assemblies or nanometer-scale structures at near-atomic resolution and in three dimensions. This imaging method covers a scale range from tens of micrometers to Ångströms and provides valuable structural information for numerous scientific disciplines including structural biology, cell biology, medical and pharmaceutical science.

The Titan Krios TEM will be publicly debuted at a symposium entitled, "Advanced Electron Microscopy in NanoMedicine," to be held October 2-3, 2009, at the EICN. Featuring in-depth talks by leading structural biologists and poster presentations by both academic and industrial researchers, the symposium will cover a wide range of topics, including: cryo-sample preparation; high-resolution cryo-electron microscopy imaging; and advances in 3D molecular reconstruction techniques, such as electron tomography and single particle analysis. For registration and additional information please visit: www.cnsi.ucla.edu/electron-microscopy/.

####

About FEI Company
FEI (Nasdaq: FEIC) is a leading diversified scientific instruments company. It is a premier provider of electron and ion-beam microscopes and tools for nanoscale applications across many industries: industrial and academic materials research, life sciences, semiconductors, data storage, natural resources and more. With a 60-year history of technological innovation and leadership, FEI has set the performance standard in transmission electron microscopes (TEM), scanning electron microscopes (SEM) and DualBeams™, which combine a SEM with a focused ion beam (FIB). FEI’s imaging systems provide 3D characterization, analysis and modification/prototyping with resolutions down to the sub-Ångström (one-tenth of a nanometer) level. FEI’s NanoPorts in North America, Europe and Asia provide centers of technical excellence where its world-class community of customers and specialists collaborate. FEI has approximately 1800 employees and sales and service operations in more than 50 countries around the world.

FEI Safe Harbor Statement

This news release contains forward-looking statements that include statements regarding the performance capabilities and benefits of the Titan Krios. Factors that could affect these forward-looking statements include but are not limited to failure of the product or technology to perform as expected and achieve anticipated results, unexpected technology problems and our ability to manufacture, ship and deliver the tools as expected. Please also refer to our Form 10-K, Forms 10-Q, Forms 8-K and other filings with the U.S. Securities and Exchange Commission for additional information on these factors and other factors that could cause actual results to differ materially from the forward-looking statements. FEI assumes no duty to update forward-looking statements.

For more information, please click here

Contacts:
Sandy Fewkes, Principal (media contact)
MindWrite Communications, Inc
+1 408 224 4024


FEI Company
Fletcher Chamberlin (investors and analysts)
Investor Relations
+1 503 726 7710

Copyright © FEI Company

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Leti Will Demonstrate First 3D Anti-Crash Solution for Embedding in Drones: Fitted on a Mass-Market Microcontroller, 360Fusion Software Technology Detects any Dynamic Obstacle and Helps Guide Drones Away from Collisions December 15th, 2017

Imaging

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

JPK Instruments announce partnership with Swiss company, Cytosurge AG. The partnership makes Cytosurge’s FluidFM® technology available on the JPK NanoWizard® AFM platform December 8th, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

Deben reports on a new publication from scientists at La Trobe University in Australia where their CT500 stage is used in micro scanning tomography experiments to better understand ceramic matrix composites under load November 29th, 2017

Announcements

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Leti Will Demonstrate First 3D Anti-Crash Solution for Embedding in Drones: Fitted on a Mass-Market Microcontroller, 360Fusion Software Technology Detects any Dynamic Obstacle and Helps Guide Drones Away from Collisions December 15th, 2017

Tools

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

JPK Instruments announce partnership with Swiss company, Cytosurge AG. The partnership makes Cytosurge’s FluidFM® technology available on the JPK NanoWizard® AFM platform December 8th, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

Events/Classes

Leti Will Demonstrate First 3D Anti-Crash Solution for Embedding in Drones: Fitted on a Mass-Market Microcontroller, 360Fusion Software Technology Detects any Dynamic Obstacle and Helps Guide Drones Away from Collisions December 15th, 2017

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Arrowhead Presents New Clinical Data Demonstrating a Sustained Host Response in Hepatitis B Patients Following RNAi Therapy — Up to 5.0 log10 reduction in HBsAg observed; data presented at HEP DART 2017 — December 6th, 2017

Leti Breakthroughs Point Way to Significant Improvements in SoC Memories December 6th, 2017

New-Contracts/Sales/Customers

Solid State Laser manufacturer Lasertel Inc. purchases an Oxford Instruments ICPCVD advanced deposition solution for improved device performance November 3rd, 2017

GLOBALFOUNDRIES and Soitec Enter Into Long-term Supply Agreement on FD-SOI Wafers: Strategic milestone to help guarantee a secure, high-volume supply of FD-SOI technology September 20th, 2017

Probiotics: Novel biosynthetic tool to develop metallic nanoparticles: This research article by Dr. Nida Akhtar et al has been published in Recent Patents on Drug Delivery & Formulation, Volume 11, Issue 1, 2017 July 20th, 2017

Here's a tip: Indented cement shows unique properties: Rice University models reveal nanoindentation can benefit crystals in concrete July 20th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project