Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > New NIH Funding to Support UAB Total Joint Replacement Research Collaboration

Yogesh Vohra
Yogesh Vohra

Abstract:
Newly announced National Institutes of Health (NIH) funding will expand the reach of ongoing University of Alabama at Birmingham (UAB) research into a unique nanostructured coating to improve the performance and longevity of total joint replacement components. The broadened UAB research opportunity is funded by a four-year, $790,931 National Institutes of Health (NIH) grant through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

New NIH Funding to Support UAB Total Joint Replacement Research Collaboration

Birmingham, AL | Posted on July 19th, 2009

UAB's research, titled Bioengineering Research Partnership (BRP) in Total Joint Replacements, will explore next-generation technology to improve the service life of total joint replacements, which UAB researchers believe could dramatically cut the number of recurrent surgical procedures performed each year, said Yogesh Vohra, Ph.D., the BRP's principal investigator and director of the Center for Nanoscale Materials and Biointegration (CNMB) in the UAB School of Natural Sciences and Mathematics.

Vohra said the BRP opportunity will unite his UAB interdisciplinary research team with professionals at Smith and Nephew Inc., an international leader in the development of advanced medical devices. The company is known globally for its OXINIUMTM oxidized zirconium material for joint replacements.

"We have been researching our nanostructured multilayer diamond coating for a number of years inside our UAB facilities but there have been limitations to just how rigorous the testing could be," Vohra said. "The funding to partner with Smith and Nephew expands our research options because it offers us access to the company's resources and talent."

Among the benefits, Vohra said, the BRP allows access to Smith and Nephew's hip and knee simulators, which offer UAB researchers the most realistic testing conditions to date for their coating technology. Working with the multi-million dollar simulators should strongly indicate how well the team's nanostructured multilayer diamond coatings reduce the friction and wear on the metal components of orthopaedic devices, Vohra said. The team also will be able to examine the cellular and tissue responses to the technology and confirm that there is no toxicity effect from any wear debris that is generated.

"This partnership is central to advancing our research toward more reliable and efficient joint replacements," Vohra said. "We are gaining access to state-of-the-art testing equipment while benefitting from Smith and Nephew's experience as the industry leader in advanced bearing-surfaces for joint replacement implants."

The BRP also helps put the UAB coating technology on the fast track for commercialization, as it will foster the private industry relationship necessary to secure investment and production capacity, Vohra said.

The overall clinical impact of the BRP research is to drive down the number of recurrent surgical procedures for joint replacement recipients, who are living longer and pushing the longevity limits of their devices, Vohra said. The American Academy of Orthopaedic Surgeons reports that 15 to 20 percent of annual total joint replacement procedures are recurrent, or revision, surgeries. Vohra said the nanostructured diamond-coated devices should reduce the metal ion release to the surrounding tissues and perform better during long-term implantation in the human body, which could significantly cut the follow-up surgery rate.

The UAB interdisciplinary research team for the project includes Vohra, Susan Bellis, Ph.D., associate professor of physiology and biophysics, Aaron Catledge, Ph.D., research assistant professor of physics, Alan Eberhardt, Ph.D., associate professor of biomedical engineering and David Moore, M.D., Division of Orthopedic Surgery.

####

About University of Alabama at Birmingham (UAB)
Known for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, the University of Alabama at Birmingham (UAB) is an internationally renowned research university and academic medical center and the state of Alabama's largest employer. For more information, please visit www.uab.edu.

For more information, please click here

Contacts:
Andrew Hayenga
(205) 934-1676

Copyright © University of Alabama at Birmingham (UAB)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Leti and Oscaro Partner on Letiís New Low-Power, Low-Cost Transceiver to Track Parcels July 12th, 2018

Oxford Instrumentsí 22 Tesla superconducting magnet system commissioned at the UAM, making it the most intense magnetic field available outside a large international facility July 12th, 2018

Govt.-Legislation/Regulation/Funding/Policy

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

Carbon is the new black: Researchers use carbon nanotubes to develop clothing that can double as batteries July 10th, 2018

High-power electronics keep their cool with new heat-conducting crystals July 6th, 2018

SUNY Poly-Led AIM Photonics and Partners Attend SEMICON West 2018 to Showcase High-Tech Advances, Collaboration, and Future R&D Opportunities: New Yorkís Tech Valley Makes a Major Showing in Silicon Valley July 3rd, 2018

Announcements

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides July 13th, 2018

Leti and Oscaro Partner on Letiís New Low-Power, Low-Cost Transceiver to Track Parcels July 12th, 2018

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

A refined magnetic sense: Algorithms and hardware developed in the context of quantum computation are shown to be useful for quantum-enhanced sensing of magnetic fields July 2nd, 2018

BNAs improve performance of Li-ion batteries June 27th, 2018

Nanomaterials could mean more algae outbreaks for wetlands, waterways: High tech metal particles may inadvertently take a toll on aquatic life June 26th, 2018

Alliances/Trade associations/Partnerships/Distributorships

Leti and Oscaro Partner on Letiís New Low-Power, Low-Cost Transceiver to Track Parcels July 12th, 2018

Leti and Soitec Launch a New Substrate Innovation Center to Develop Engineered Substrate Solutions: Industry-inclusive hub promotes early collaboration and learning from substrate to system level July 11th, 2018

Leti & Partners Launch Pilot Program to Assess New Perception Sensors for Autonomous Vehicles July 5th, 2018

Powering the 21st Century with Integrated Photonics: UCSB-Led Team Selected for Demonstration of a Novel Waveguide Platform Which is Transparent Throughout the MWIR and LWIR Spectral Bands June 19th, 2018

Research partnerships

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

Leti and Soitec Launch a New Substrate Innovation Center to Develop Engineered Substrate Solutions: Industry-inclusive hub promotes early collaboration and learning from substrate to system level July 11th, 2018

Leti & Partners Launch Pilot Program to Assess New Perception Sensors for Autonomous Vehicles July 5th, 2018

A refined magnetic sense: Algorithms and hardware developed in the context of quantum computation are shown to be useful for quantum-enhanced sensing of magnetic fields July 2nd, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project