Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Study on cytotoxicity of carbon nanotubes

Abstract:
Owing to the novel properties of carbon nanotubes (CBNs), a series of problems associated with in vitro toxicity assessments of carbon nanotubes (CNTs) have appeared in many literatures. In order to properly evaluate the potential risk to human health, the cell toxicity assay of CBNs can not be conducted by traditional methods employed in common toxicology.

Study on cytotoxicity of carbon nanotubes

China | Posted on December 22nd, 2008

Ying Zhu and Wenxin Li in Laboratory of Nano-biology and Medicine, Shanghai Institute of Applied Physics, Shanghai, P. R.China gave this point of view in their review articles. This paper, "Study on Cytotoxicity of Carbon Nanotubes" was published in Issue 51 (November, 2008) of the Science in China Series B: Chemistry .

With their production and application at large scale, CNTs may cause adverse response to the environment and human health. Thus, the study on bio-effects and safety of CNTs has attracted great attention from scientists and governments worldwide. Unfortunately experimental information obtained thus far on CNTs' cytotoxicity is often lack of comparability, or even in contradiction.

This paper systematically reviewed most of the experimental results reported in the literatures. The emphasis was placed on the examination of a variety of factors affecting CNTs cytotoxicity, including species of CNTs, impurities contained, lengths of CNTs, aspect ratios, chemical modification, and assaying methods of cytotoxicity. Based on analysis of the research status on cytotoxicity of CNTs, the authors suggested that care should be taken for several issues such as chemical modification and realistic exposure, more complete and quantified characterization of CNTs, determination methods of cell viability. More importantly, the studies on physical and chemical mechanisms of CNTs' cytotoxicity should be strengthened.

In view of novel properties of CNTs, namely huge surface areas, high adsorption activity, and great ability of internalization into cells, CNTs are able to deliver various molecules in surroundings which usually can not enter cells due to poor cell permeability, into the cell interior and then effectively perform their biological activity. Accordingly "nanotoxicology should have its own characteristics differing from common toxicology in respect to research thinking, assay methods, technical routes, and evaluation criteria", as pointed out by the authors in this paper. Finally, the authors hoped that the scientists should deeply understand the uniqueness of nanomaterials, enhance the collaboration of physics, chemistry and toxicology, and push forward the study of nanotoxicology with the goal of making contribution to application of nanoscience and nanotechnology in various fields of national economy.

This work was supported by the National Natural Science Foundation of China (Nos.10475109 and 10775169), Shanghai Municipal Commission for Science and Technology (Nos. 0552nm033, 0652nm016 and 0752nm021) and MOST973 Program (No. 2006CB705605).

This paper deserves publication because the dissertation is sound, and the topic attracted the public interesting, concerning in nanoscience, environment, and health. In addition, the main ideals delivery in this paper bridged over a gap between the substance science and the life science in the frame of nanoscience and technology.

Reference: Zhu Y, Li WX. Cytotoxicity of carbon nanotubes. Science in China Series B: Chemistry, 2008; 51(11): 1021-1029 dx.doi.org/10.1007/s11426-008-0120-6

####

For more information, please click here

Contacts:
Wen-Xin Li

0086-235-955-7530

Copyright © Science in China Press

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Govt.-Legislation/Regulation/Funding/Policy

Wheat gets boost from purified nanotubes: Rice University toxicity study shows plant growth enhanced by -- but only by -- purified nanotubes December 6th, 2017

Arrowhead Presents New Clinical Data Demonstrating a Sustained Host Response in Hepatitis B Patients Following RNAi Therapy — Up to 5.0 log10 reduction in HBsAg observed; data presented at HEP DART 2017 — December 6th, 2017

Chinese market opens up for Carbodeon nanodiamonds: Carbodeon granted Chinese Patent for Nanodiamond-containing Thermoplastic Thermal Compounds December 4th, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

Nanotubes/Buckyballs/Fullerenes/Nanorods

Scientists make transparent materials absorb light December 1st, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

NanoSummit in Luxembourg: single wall carbon nanotubes have entered our lives as we approach a nanoaugmented future November 23rd, 2017

Fine felted nanotubes : Research team of Kiel University develops new composite material made of carbon nanotubes November 22nd, 2017

Announcements

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Environment

Silicon Sense first to achieve EPA approval to import detonation nanodiamonds to US: Nanodiamond additives can significantly improve the performance of metal finishing, polymer thermal and mechanical compounds, polymer coatings, CMP polishing and a range of other applications November 29th, 2017

Report highlights opportunities and risks associated with synthetic biology and bioengineering November 22nd, 2017

Dendritic fibrous nanosilica: all-in-one nanomaterial for energy, environment and health November 4th, 2017

Nano-sized gold particles have been shaped to behave as clones in biomedicine November 3rd, 2017

Safety-Nanoparticles/Risk management

How harmful are nano-copper and anti-fungal combinations in the waterways? October 27th, 2017

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Tests show no nanotubes released during utilisation of nanoaugmented materials June 9th, 2017

NanoMONITOR shares its latest developments concerning the NanoMONITOR Software and the Monitoring stations April 21st, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project