Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Study on cytotoxicity of carbon nanotubes

Abstract:
Owing to the novel properties of carbon nanotubes (CBNs), a series of problems associated with in vitro toxicity assessments of carbon nanotubes (CNTs) have appeared in many literatures. In order to properly evaluate the potential risk to human health, the cell toxicity assay of CBNs can not be conducted by traditional methods employed in common toxicology.

Study on cytotoxicity of carbon nanotubes

China | Posted on December 22nd, 2008

Ying Zhu and Wenxin Li in Laboratory of Nano-biology and Medicine, Shanghai Institute of Applied Physics, Shanghai, P. R.China gave this point of view in their review articles. This paper, "Study on Cytotoxicity of Carbon Nanotubes" was published in Issue 51 (November, 2008) of the Science in China Series B: Chemistry .

With their production and application at large scale, CNTs may cause adverse response to the environment and human health. Thus, the study on bio-effects and safety of CNTs has attracted great attention from scientists and governments worldwide. Unfortunately experimental information obtained thus far on CNTs' cytotoxicity is often lack of comparability, or even in contradiction.

This paper systematically reviewed most of the experimental results reported in the literatures. The emphasis was placed on the examination of a variety of factors affecting CNTs cytotoxicity, including species of CNTs, impurities contained, lengths of CNTs, aspect ratios, chemical modification, and assaying methods of cytotoxicity. Based on analysis of the research status on cytotoxicity of CNTs, the authors suggested that care should be taken for several issues such as chemical modification and realistic exposure, more complete and quantified characterization of CNTs, determination methods of cell viability. More importantly, the studies on physical and chemical mechanisms of CNTs' cytotoxicity should be strengthened.

In view of novel properties of CNTs, namely huge surface areas, high adsorption activity, and great ability of internalization into cells, CNTs are able to deliver various molecules in surroundings which usually can not enter cells due to poor cell permeability, into the cell interior and then effectively perform their biological activity. Accordingly "nanotoxicology should have its own characteristics differing from common toxicology in respect to research thinking, assay methods, technical routes, and evaluation criteria", as pointed out by the authors in this paper. Finally, the authors hoped that the scientists should deeply understand the uniqueness of nanomaterials, enhance the collaboration of physics, chemistry and toxicology, and push forward the study of nanotoxicology with the goal of making contribution to application of nanoscience and nanotechnology in various fields of national economy.

This work was supported by the National Natural Science Foundation of China (Nos.10475109 and 10775169), Shanghai Municipal Commission for Science and Technology (Nos. 0552nm033, 0652nm016 and 0752nm021) and MOST973 Program (No. 2006CB705605).

This paper deserves publication because the dissertation is sound, and the topic attracted the public interesting, concerning in nanoscience, environment, and health. In addition, the main ideals delivery in this paper bridged over a gap between the substance science and the life science in the frame of nanoscience and technology.

Reference: Zhu Y, Li WX. Cytotoxicity of carbon nanotubes. Science in China Series B: Chemistry, 2008; 51(11): 1021-1029 dx.doi.org/10.1007/s11426-008-0120-6

####

For more information, please click here

Contacts:
Wen-Xin Li

0086-235-955-7530

Copyright © Science in China Press

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

Govt.-Legislation/Regulation/Funding/Policy

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

'Electronic skin' could improve early breast cancer detection October 29th, 2014

Nanotubes/Buckyballs

Tiny carbon nanotube pores make big impact October 29th, 2014

Materials for the next generation of electronics and photovoltaics: MacArthur Fellow develops new uses for carbon nanotubes October 21st, 2014

Special UO microscope captures defects in nanotubes: University of Oregon chemists provide a detailed view of traps that disrupt energy flow, possibly pointing toward improved charge-carrying devices October 21st, 2014

Imaging electric charge propagating along microbial nanowires October 20th, 2014

Announcements

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

Environment

Microrockets fueled by water neutralize chemical and biological warfare agents October 29th, 2014

Nanoparticles Display Ability to Improve Efficiency of Filters October 28th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Imaging electric charge propagating along microbial nanowires October 20th, 2014

Safety-Nanoparticles/Risk management

Nanosafety research – there’s room for improvement October 29th, 2014

Plastic nanoparticles also harm freshwater organisms October 18th, 2014

Human health, wealth require expanded marine science, experts say: In Rome, European experts publish a 'common vision' of priorities for marine research and action through 2020 October 9th, 2014

Coating Nanotubes with Aluminum Oxide Lowers Risk of Lung Injury October 6th, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE