Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > NC State finds new nanomaterial could be breakthrough for implantable medical devices

Abstract:
A team of researchers led by North Carolina State University has made a breakthrough that could lead to new dialysis devices and a host of other revolutionary medical implants. The researchers have found that the unique properties of a new material can be used to create new devices that can be implanted into the human body - including blood glucose sensors for diabetics and artificial hemo-dialysis membranes that can scrub impurities from the blood.

NC State finds new nanomaterial could be breakthrough for implantable medical devices

Raleigh, NC | Posted on November 10th, 2008

Researchers have long sought to develop medical devices that could be implanted into patients for a variety of purposes, such as monitoring glucose levels in diabetic patients. However, existing materials present significant problems. For example, devices need to be made of a material that prevents the body's proteins from building up on sensors and preventing them from working properly. And any implanted device also needs to avoid provoking an inflammatory response from the body that would result in the body's walling off the device or rejecting it completely.

Now a new study finds that nanoporous ceramic membranes may be used to resolve these issues. Dr. Roger Narayan - an associate professor in the joint biomedical engineering department of NC State and the University of North Carolina at Chapel Hill - led the research and says the nanoporous membranes could be used to "create an interface between human tissues and medical devices that is free of protein buildup."

The new research, published in a special issue of Biomedical Materials, is the first in-depth study of the biological and physical properties of the membranes. The study suggests that the human body will not reject the nanoporous ceramic membrane. Narayan adds that this could be a major advance for the development of kidney dialysis membranes and other medical devices whose development has been stalled by poor compatibility with human tissues. Narayan was also the lead researcher on the team that first developed these new materials.

Narayan's co-authors on the paper include NC State materials science engineering doctoral students Ravi Aggarwal and Wei Wei; NC State postdoctoral research associate Dr. Chunming Jin; Dr. Nancy Monteiro-Riviere, professor of investigative dermatology and toxicology at NC State's College of Veterinary Medicine and the Center for Chemical Toxicology Research and Pharmacokinetics; and Rene Crombez and Dr. Weidian Shen of Eastern Michigan University.

Note to editors: The study abstract follows.

"Mechanical and biological properties of nanoporous carbon membranes"

Authors: Dr. Roger J. Narayan, Ravi Aggarwal, Wei Wei, Dr. Chunming Jin, Dr. Nancy A. Monteiro-Riviere, North Carolina State University; Rene Crombez, Dr. Weidian Shen, Eastern Michigan University
Published: Aug. 8, 2008, in Biomedical Materials
Abstract: Implantable blood glucose sensors have inadequate membrane-tissue interfaces for long term use. Biofouling and inflammation processes restrict biosensor membrane stability. An ideal biosensor membrane material must prevent protein adsorption and exhibit cell compatibility. In addition, a membrane must exhibit high porosity and low thickness in order to allow the biosensor to respond to analyte fluctuations. In this study, the structural, mechanical and biological properties of nanoporous alumina membranes coated with diamond-like carbon thin films were examined using scanning probe microscopy, nanoindentation and MTT viability assay. We anticipate that this novel membrane material could find use in immunoisolation devices, kidney dialysis membranes and other medical devices encountering biocompatibility issues that limit in vivo function.

####

For more information, please click here

Contacts:
Matt Shipman

919-515-6386

Copyright © North Carolina State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Nanomedicine

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Made-in-Singapore rapid test kit detects dengue antibodies from saliva: IBN's MedTech innovation simplifies diagnosis of infectious diseases January 29th, 2015

Iranian Researchers Planning to Produce Edible Insulin January 28th, 2015

Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics January 28th, 2015

Discoveries

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Materials/Metamaterials

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

The Original Frameless Shower Doors Installs DFI's FuseCube™ to Offer Hydrophobic Protective Coating as a Standard Feature: First DFI FuseCube™ Installed on the East Coast to Enable Key Differentiator for the Original Frameless Shower Doors January 29th, 2015

Creating new materials with quantum effects for electronics January 29th, 2015

Announcements

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE