Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Researcher Looks For Better Way to Kill Cancer Cells

Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles.  The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.
Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles. The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.

Abstract:
NIH Award Helps Fund Study of Treatments Using Magnetic Nanoparticles

Researcher Looks For Better Way to Kill Cancer Cells

Dallas, TX | Posted on October 13th, 2008

Physics Professor Diandra Leslie-Pelecky brought more with her when she arrived at UT Dallas than expertise in nanotechnology and shiny behemoth lab equipment. She brought an award for $84,000 from the National Institutes of Health via the Cleveland Clinic.

"This avenue of research focuses on treatments for breast cancer and prostate cancer," Leslie-Pelecky said. "These cancers usually present tumors that are close to the skin. If we can deliver magnetic, cancer-fighting drugs directly to these tumors—and if we can keep the drugs in place at the tumor sites with magnets—we can avoid some of the side-effects of giving people cancer drugs that end up distributed through their entire body."

Leslie-Pelecky said the basic principles of this treatment are established, but a few roadblocks remain.

"One challenge is making nanoparticles that are more magnetic," she said. "We really have to understand the basic physics at work so we can design strongly magnetic nanoparticles. We're fighting blood flow that will carry treatments away from tumors, so we need stronger magnetic nanoparticles that will stay in place, and keep the chemotherapy drugs in place, when we hold a magnet on the outside of the skin."

Another possible roadblock the research team faced was determining whether iron-oxide nanoparticles presented any harmful effects inside the body. The study concluded that the MNPs generated didn't cause long-term changes in liver enzyme levels or induce oxidative stress and were therefore safe for drug delivery or other applications.

Leslie-Pelecky custom tailors iron oxide nanoparticles in a stainless steel deposition chamber housed in her lab at UT Dallas. Labhasetwar supplies the medical expertise for their collaboration, while Leslie-Pelecky focuses on magnetic nanotechnology and precisely manufacturing the research particles.

The collaboration resulted in a paper, published in Molecular Pharmaceutics, that was recently cited among the most-accessed articles in the first quarter of 2008.

####

For more information, please click here

Contacts:
Brandon V. Webb
UT Dallas
(972) 883-2155


Office of Media Relations
UT Dallas
(972) 883-2155

Copyright © UT Dallas

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Hiden Release New Gas Analysis Catalogue August 21st, 2014

Wyatt Technology’s 24th International Light Scattering Colloquium to Highlight Developments in Applications and Characterization of Nanoparticles August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Govt.-Legislation/Regulation/Funding/Policy

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Success in Intracellular Imaging of Cesium Distribution in Plants Used for Cesium Absorption August 19th, 2014

Electrical engineers take major step toward photonic circuits: Team invents non-metallic metamaterial that enables them to 'compress' and contain light August 19th, 2014

Promising Ferroelectric Materials Suffer From Unexpected Electric Polarizations: Brookhaven Lab scientists find surprising locked charge polarizations that impede performance in next-gen materials that could otherwise revolutionize data-driven devices August 18th, 2014

Nanomedicine

Ultra-short pulse lasers & Positioning August 21st, 2014

Nanotechnology Helps Production of Super Adsorbent Polymers August 21st, 2014

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Graphene rubber bands could stretch limits of current healthcare, new research finds August 19th, 2014

Discoveries

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Nanotechnology Helps Production of Super Adsorbent Polymers August 21st, 2014

Rice physicist emerges as leader in quantum materials research: Nevidomskyy wins both NSF CAREER Award and Cottrell Scholar Award August 20th, 2014

Announcements

Wyatt Technology’s 24th International Light Scattering Colloquium to Highlight Developments in Applications and Characterization of Nanoparticles August 21st, 2014

Ultra-short pulse lasers & Positioning August 21st, 2014

Malvern’s Dr Alan Rawle talks TLAs in plenary lecture at Particulate Systems Analysis conference August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Rice physicist emerges as leader in quantum materials research: Nevidomskyy wins both NSF CAREER Award and Cottrell Scholar Award August 20th, 2014

Oxford Instruments Asylum Research Receives the 2014 Microscopy Today Innovation Award for blueDrive Photothermal Excitation August 18th, 2014

AQUANOVA receives Technology Leadership Award 2014 FROST & SULLIVAN honors NovaSOL® Technology again August 12th, 2014

Focal blood-brain-barrier disruption with high-frequency pulsed electric fields August 12th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE