Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Researcher Looks For Better Way to Kill Cancer Cells

Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles.  The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.
Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles. The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.

Abstract:
NIH Award Helps Fund Study of Treatments Using Magnetic Nanoparticles

Researcher Looks For Better Way to Kill Cancer Cells

Dallas, TX | Posted on October 13th, 2008

Physics Professor Diandra Leslie-Pelecky brought more with her when she arrived at UT Dallas than expertise in nanotechnology and shiny behemoth lab equipment. She brought an award for $84,000 from the National Institutes of Health via the Cleveland Clinic.

"This avenue of research focuses on treatments for breast cancer and prostate cancer," Leslie-Pelecky said. "These cancers usually present tumors that are close to the skin. If we can deliver magnetic, cancer-fighting drugs directly to these tumors—and if we can keep the drugs in place at the tumor sites with magnets—we can avoid some of the side-effects of giving people cancer drugs that end up distributed through their entire body."

Leslie-Pelecky said the basic principles of this treatment are established, but a few roadblocks remain.

"One challenge is making nanoparticles that are more magnetic," she said. "We really have to understand the basic physics at work so we can design strongly magnetic nanoparticles. We're fighting blood flow that will carry treatments away from tumors, so we need stronger magnetic nanoparticles that will stay in place, and keep the chemotherapy drugs in place, when we hold a magnet on the outside of the skin."

Another possible roadblock the research team faced was determining whether iron-oxide nanoparticles presented any harmful effects inside the body. The study concluded that the MNPs generated didn't cause long-term changes in liver enzyme levels or induce oxidative stress and were therefore safe for drug delivery or other applications.

Leslie-Pelecky custom tailors iron oxide nanoparticles in a stainless steel deposition chamber housed in her lab at UT Dallas. Labhasetwar supplies the medical expertise for their collaboration, while Leslie-Pelecky focuses on magnetic nanotechnology and precisely manufacturing the research particles.

The collaboration resulted in a paper, published in Molecular Pharmaceutics, that was recently cited among the most-accessed articles in the first quarter of 2008.

####

For more information, please click here

Contacts:
Brandon V. Webb
UT Dallas
(972) 883-2155


Office of Media Relations
UT Dallas
(972) 883-2155

Copyright © UT Dallas

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Govt.-Legislation/Regulation/Funding/Policy

These microscopic fish are 3-D-printed to do more than swim: Researchers demonstrate a novel method to build microscopic robots with complex shapes and functionalities August 26th, 2015

Glitter from silver lights up Alzheimer's dark secrets August 25th, 2015

Southampton scientists find new way to detect ortho-para conversion in water August 25th, 2015

Industrial Nanotech, Inc. Provides Update On Hospital Project, PCAOB Audit, and New Heat Shield™ Line August 24th, 2015

Nanomedicine

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

These microscopic fish are 3-D-printed to do more than swim: Researchers demonstrate a novel method to build microscopic robots with complex shapes and functionalities August 26th, 2015

Discoveries

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

CWRU researchers efficiently charge a lithium-ion battery with solar cell: Coupling with perovskite solar cell holds potential for cleaner cars and more August 27th, 2015

Announcements

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

50 Years of Scanning Electron Microscopy from ZEISS: ZEISS celebrates the birth of the first commercial scanning electron microscope in 1965 August 26th, 2015

How UEA research could help build computers from DNA August 19th, 2015

'Quantum dot' technology may help light the future August 19th, 2015

Exercise-induced hormone irisin is not a 'myth' August 14th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic