Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Researcher Looks For Better Way to Kill Cancer Cells

Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles.  The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.
Professor Diandra Leslie-Pelecky uses this deposition chamber to make nanoparticles. The operation resembles the process that occurs when a piece of glass is placed over boiling water, except that instead of steam, it condenses metal vapor.

Abstract:
NIH Award Helps Fund Study of Treatments Using Magnetic Nanoparticles

Researcher Looks For Better Way to Kill Cancer Cells

Dallas, TX | Posted on October 13th, 2008

Physics Professor Diandra Leslie-Pelecky brought more with her when she arrived at UT Dallas than expertise in nanotechnology and shiny behemoth lab equipment. She brought an award for $84,000 from the National Institutes of Health via the Cleveland Clinic.

"This avenue of research focuses on treatments for breast cancer and prostate cancer," Leslie-Pelecky said. "These cancers usually present tumors that are close to the skin. If we can deliver magnetic, cancer-fighting drugs directly to these tumorsóand if we can keep the drugs in place at the tumor sites with magnetsówe can avoid some of the side-effects of giving people cancer drugs that end up distributed through their entire body."

Leslie-Pelecky said the basic principles of this treatment are established, but a few roadblocks remain.

"One challenge is making nanoparticles that are more magnetic," she said. "We really have to understand the basic physics at work so we can design strongly magnetic nanoparticles. We're fighting blood flow that will carry treatments away from tumors, so we need stronger magnetic nanoparticles that will stay in place, and keep the chemotherapy drugs in place, when we hold a magnet on the outside of the skin."

Another possible roadblock the research team faced was determining whether iron-oxide nanoparticles presented any harmful effects inside the body. The study concluded that the MNPs generated didn't cause long-term changes in liver enzyme levels or induce oxidative stress and were therefore safe for drug delivery or other applications.

Leslie-Pelecky custom tailors iron oxide nanoparticles in a stainless steel deposition chamber housed in her lab at UT Dallas. Labhasetwar supplies the medical expertise for their collaboration, while Leslie-Pelecky focuses on magnetic nanotechnology and precisely manufacturing the research particles.

The collaboration resulted in a paper, published in Molecular Pharmaceutics, that was recently cited among the most-accessed articles in the first quarter of 2008.

####

For more information, please click here

Contacts:
Brandon V. Webb
UT Dallas
(972) 883-2155


Office of Media Relations
UT Dallas
(972) 883-2155

Copyright © UT Dallas

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Designing ultrasound tools with Lego-like proteins August 29th, 2016

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Govt.-Legislation/Regulation/Funding/Policy

Analog DNA circuit does math in a test tube: DNA computers could one day be programmed to diagnose and treat disease August 25th, 2016

New approach to determining how atoms are arranged in materials August 25th, 2016

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer August 25th, 2016

New electrical energy storage material shows its power: Nanomaterial combines attributes of both batteries and supercapacitors August 25th, 2016

Nanomedicine

Designing ultrasound tools with Lego-like proteins August 29th, 2016

Nanofiber scaffolds demonstrate new features in the behavior of stem and cancer cells August 25th, 2016

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer August 25th, 2016

50 years after the release of the film 'Fantastic Voyage,' science upstages fiction: Science upstages fiction with nanorobotic agents designed to travel in the human body to treat cancer August 25th, 2016

Discoveries

Designing ultrasound tools with Lego-like proteins August 29th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

New electrical energy storage material shows its power: Nanomaterial combines attributes of both batteries and supercapacitors August 25th, 2016

Announcements

Designing ultrasound tools with Lego-like proteins August 29th, 2016

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

New electrical energy storage material shows its power: Nanomaterial combines attributes of both batteries and supercapacitors August 25th, 2016

Light and matter merge in quantum coupling: Rice University physicists probe photon-electron interactions in vacuum cavity experiments August 24th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic