Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nanoscopic screening process to speed drug discovery

Wake Forest University physics professors (from left to right) Martin Guthold, Keith Bonin and Jed Macasko work in Guthold's laboratory on development of Lab-on-Bead processing, a novel drug-screening technique with the potential to be 10,000 times faster than current methods.
Wake Forest University physics professors (from left to right) Martin Guthold, Keith Bonin and Jed Macasko work in Guthold's laboratory on development of Lab-on-Bead processing, a novel drug-screening technique with the potential to be 10,000 times faster than current methods.

Abstract:
Researchers at Wake Forest University are using nanotechnology to search for new cancer-fighting drugs through a process that could be up to 10,000 times faster than current methods.

The "Lab-on-Bead" process will screen millions of chemicals simultaneously using tiny plastic beads so small that 1,000 of them would fit across a human hair. Each bead carries a separate chemical, which can be identified later if it displays the properties needed to treat cancer cells. One batch of nanoscopic beads can replace the work of thousands of conventional, repetitive laboratory tests.

Nanoscopic screening process to speed drug discovery

Winston-Salem, NC | Posted on October 6th, 2008

"This process allows the beads to do the work for you," explains Jed Macosko, project director and assistant professor of physics at Wake Forest. "By working at this scale, we will be able to screen more than a billion possible drug candidates per day as opposed to the current limit of hundreds of thousands per day."

Other members of the research team at Wake Forest include co-principal investigator Martin Guthold, an associate professor of physics, and Keith Bonin, department chair and professor of physics.

Macosko said the team and their collaborators at the University of Waterloo in Ontario, Canada, are developing a device that will automate the Lab-on-Bead process and permit parallel processing to attain faster screening results. The Wake Forest researchers are also working with biotechnologists at Harvard University in Boston and Université Louis Pasteur in Strasbourg, France, which are providing the chemicals being screened for drug candidates. Biotech company NanoMedica has shown interest in commercializing the process. The North Carolina Biotechnology Center, a private, nonprofit corporation funded by the N.C. General Assembly, has provided $75,000 in funding for the project.

Wake Forest's Center for Nanotechnology and Molecular Materials, which maintains ongoing research programs in the areas of health and medicine, energy technologies and synthesis of nanomaterials, will facilitate some elements of Lab-on-Bead development.

####

For more information, please click here

Contacts:
Eric Frazier
(336) 758-5237


Kevin Cox
(336) 758-5237

Copyright © Wake Forest University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

X-ray photoelectron spectroscopy under real ambient pressure conditions June 28th, 2017

Nanometrics to Participate in the 9th Annual CEO Investor Summit 2017: Accredited investor and publishing research analyst event held concurrently with SEMICON West and Intersolar 2017 in San Francisco June 27th, 2017

NMRC, University of Nottingham chooses the Quorum Q150 coater for its reliable and reproducible film thickness when coating samples with iridium June 27th, 2017

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

Nanomedicine

Physicists make quantum leap in understanding life's nanoscale machinery June 27th, 2017

Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017

Learning with light: New system allows optical “deep learning”: Neural networks could be implemented more quickly using new photonic technology June 12th, 2017

Mussels add muscle to biocompatible fibers: Rice University chemists develop hydrogel strings using compound found in sea creatures June 9th, 2017

Discoveries

X-ray photoelectron spectroscopy under real ambient pressure conditions June 28th, 2017

Physicists make quantum leap in understanding life's nanoscale machinery June 27th, 2017

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

Atomic imperfections move quantum communication network closer to reality June 25th, 2017

Announcements

X-ray photoelectron spectroscopy under real ambient pressure conditions June 28th, 2017

Nanometrics to Participate in the 9th Annual CEO Investor Summit 2017: Accredited investor and publishing research analyst event held concurrently with SEMICON West and Intersolar 2017 in San Francisco June 27th, 2017

NMRC, University of Nottingham chooses the Quorum Q150 coater for its reliable and reproducible film thickness when coating samples with iridium June 27th, 2017

Picosun’s ALD solutions enable novel high-speed memories June 27th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project