Home > Press > UNM Researchers Awarded $1.1 Million Grant to Build Optical Scanning Nanoscope
Abstract:
Instrument to provide real-time images of biological processes
Researchers at the University of New Mexico were recently awarded a three-year, $1.1 million grant from the W.M. Keck Foundation to support a research program within the Department of Physics. The program, titled "A Facility to Perform Bio-molecular Imaging; Real Time Phase Mapping of Biological Dynamics," is designed to provide real-time images of biological processes at nano and pico scale resolutions, a feat never achieved before.
Research Ramifications
It is anticipated that this new phase mapping method will have an impact on medical imaging similar to that of magnetic resonance imaging (MRI).
"We're building from scratch an instrument for the UNM Cancer Research and Treatment Center that will make an optical image with a resolution of better than one nanometer," said Physics Professor Jean Claude-Diels, the lead investigator in the program. "This is considerably less than the wavelength of light, which is generally considered to be the resolution limit for imaging."
Hundreds of potential research questions could be answered with the Scanning Phase Intracavity Nanoscope or SPIN, which will be capable of visualizing the components of living cells. The instrument itself is a breakthrough utilizing properties never exploited before. The novel compact instrument will sample any host material, water or tissue, with no sample preparation required, and with no harmful radiation such as x-rays or high-energy radiation particle beams.
"Seeing is understanding," says Diels. "Therefore, we want to be able to see with our eyes what happens in the nanoscale in living organisms. For instance, we could see the details in the cell membrane. In the membrane you can see a very important path of the cell activity. We could see how a virus penetrates the membrane."
Meet the Researchers
In addition to Diels, who has developed the concept of intra-cavity sensors with pulsed lasers critical in the applications of the instrument, Physics Professor Sudhakar Prasad will perform efficient image and data compression for the imaging. His assistance will be invaluable in achieving image reconstruction with the extreme data compression needed for the application. Keith Lidke, an assistant professor in Physics and Astronomy, will provide expertise in high-resolution optical imaging and will manage hardware integration
The interdisciplinary collaboration also includes researchers in UNM's Cancer Research and Treatment Center (CRTC), and the Center for High Technology Materials (CHTM). At CRTC, Dr. Janet Oliver has enthusiastically supported the project, and CRTC Director Dr. Cheryl Willman has secured future housing and technician support for the instrument.
Professor and CHTM Director Steve Brueck is supporting the construction, housing of the research with the formidable facilities at the CHTM, as well as participating in the scientific development. Ladan Arissian, a research scientist also at the CHTM, has been instrumental in the development of the various inventions with Diels, and will supervise the students who will be involved in the construction of the nanoscope.
Assistant Professor Diane Lidke, an expert in cell biology and membranes, who will provide the biological samples for testing and validating the instrument, fortifies the bridge between the worlds of biology and physics.
The Keck Foundation
Based in Los Angeles, the W. M. Keck Foundation was established in 1954 by the late W. M. Keck, founder of the Superior Oil Company. The Foundation's grant making is focused primarily on pioneering efforts in the areas of medical research, science and engineering.
The Foundation also maintains a program to support undergraduate science and humanities education and a Southern California Grant Program that provides support in the areas of health care, civic and community services, education and the arts, with a special emphasis on children and youth.
####
About University of New Mexico
Founded in 1889, The University of New Mexico now occupies 600 acres along old Route 66 in the heart of Albuquerque , a city of more than 700,000 people. From the magnificent mesas to the west, past the banks of the historic Rio Grande to the Sandia Mountains to the east, Albuquerque is a blend of culture and cuisine, styles and stories, people, pursuits and panoramas.
For more information, please click here
Contacts:
Steve Carr
(505) 277-1821
Copyright © University of New Mexico
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related News Press |
News and information
Researchers develop artificial building blocks of life March 8th, 2024
Imaging
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
The USTC realizes In situ electron paramagnetic resonance spectroscopy using single nanodiamond sensors November 3rd, 2023
Observation of left and right at nanoscale with optical force October 6th, 2023
Academic/Education
Rice University launches Rice Synthetic Biology Institute to improve lives January 12th, 2024
Multi-institution, $4.6 million NSF grant to fund nanotechnology training September 9th, 2022
Announcements
What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Tools
Ferroelectrically modulate the Fermi level of graphene oxide to enhance SERS response November 3rd, 2023
The USTC realizes In situ electron paramagnetic resonance spectroscopy using single nanodiamond sensors November 3rd, 2023
Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records
'Sudden death' of quantum fluctuations defies current theories of superconductivity: Study challenges the conventional wisdom of superconducting quantum transitions January 12th, 2024
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||