Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

Abstract:
Pitt joins North Carolina A&T and University of Cincinnati in $18.5 million effort to create orthopedic, craniofacial, and cardiovascular devices that adapt to a patient's anatomy and dissolve when no longer needed

A&T first historically Black college to receive prestigious Engineering Research Center grant from NSF


Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

PITTSBURGH, PA | Posted on September 5th, 2008

University of Pittsburgh researchers will help lead dozens of engineers and doctors from universities and industries around the world for a five-year, $18.5 million project announced Sept. 4 to develop implantable devices made from biodegradable metals. The devices will be designed to adapt to physical changes in a patient's body and dissolve once they have healed, reducing the follow-up surgeries and potential complications of major orthopedic, craniofacial, and cardiovascular procedures and sparing millions of patients worldwide added pain and medical expenses.

Pitt belongs to the project's central partnership along with the University of Cincinnati (UC) and the project's lead institution, North Carolina Agricultural and Technical State University (NCAT). Serving as deputy director is William Wagner, deputy director of Pitt's McGowan Institute for Regenerative Medicine and professor of surgery, bioengineering, and chemical engineering in the Swanson School of Engineering.

"The treatment of diseased and traumatized tissues is evolving as medical technologies increasingly harness the body's regenerative powers," Wagner said. "This effort will extend this approach by combining the mechanical attributes of metals with biologically active agents that together will further encourage the natural healing process."

Jagannathan Sankar, NCAT's Distinguished University Professor of mechanical engineering and director of the Center for Advanced Materials and Smart Structures, will direct the project with UC professor Mark Schulz, codirector of the UC Nanoworld and Smart Materials and Devices Laboratories, joining Wagner as deputy director.

The project stems from a five-year Engineering Research Center (ERC) grant NCAT received from the National Science Foundation (NSF) in collaboration with Pitt and UC. The highly competitive ERC grant supports large-scale university and industry collaborations on pioneering technologies. Five grants were awarded this year from 143 applicants and only 29 universities in the past 25 years have received an ERC. NCAT is the first Historically Black College and University (HCBU) to become an ERC. To coincide with the grant project, NCAT will establish the first bioengineering department at an HCBU with the assistance of faculty members in Pitt's Department of Bioengineering, McGowan Institute for Regenerative Medicine, and at UC. The department will offer bachelor's, master's, and PhD degrees.

The ERC project will focus primarily on producing three technologies: biodegradable and self-adapting devices and smart constructs for craniofacial and orthopedic reconstructive procedures, similarly behaving cardiovascular devices such as stents, and miniaturized sensing systems that monitor and control the safety and effectiveness of biodegradable metals inside the body (a technology that could lead to responsive biosensors that help doctors determine when and where diseases occur in the body).

The biodegradable devices and smart structures are intended to reduce complications and spare patients with conditions ranging from cleft palate and bone fractures to coronary heart disease from undergoing multiple surgeries. For instance, children born with a cleft palate are fitted with hard metal devices that must be removed and refitted over time. Devices the ERC researchers will explore-crafted from magnesium alloys and other biodegradable metals-would adapt to the body without refitting. Plus, magnesium alloys dissolve after their work is done with no clinical side effects, a feature also beneficial in the cardiovascular realm. Magnesium stents and other supports would restore cardiovascular function without having to remove the device and without exposing the patient to the potential complications of leaving it inside the body.

The project pools Pitt's strength in biomaterials and regenerative medicine stemming from the work conducted in the Swanson School's Departments of Bioengineering, Chemical Engineering, and Mechanical Engineering and Material Sciences, the McGowan Institute for Regenerative Medicine, and the School of Dental Medicine with NCAT's recognized expertise in metallurgy and UC's research in nano- and sensor technology.

"This project builds on two of the most important research areas in the Swanson School, bio- and mechanical engineering," said Gerald Holder, Pitt's U.S. Steel Dean of Engineering. "We are proud to be a part of the team developing the technology that will help people by improving many medical procedures. The impact on our local economy, which is highly dependent on medical-based development, will be very significant. New companies will result from the research done through this ERC, companies that will continue to conduct research, manufacture medical devices, and develop advanced procedures and technology."

Other partners include Germany's Hannover Medical School for support in medical implantology. The Indian Institute of Technology in Madras, India, will provide a global prospective on the research and application of nano- and biomaterials. California State University at Los Angeles, a designated Hispanic Serving Institution, will conduct bioscience research to help engage underrepresented students.

Nearly 30 product development and industrial partners in the nano- and biotechnology market will form a consortium with ERC to provide input for the direction of research and to help transfer ERC technology to patients.

####

For more information, please click here

Contacts:
Morgan Kelly
412-624-4356 (office)
412-897-1400 (cell)

Copyright © University of Pittsburgh

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Harris & Harris Group to Host Conference Call on Second-Quarter 2014 Financial Results on August 15, 2014 July 23rd, 2014

UCF Nanotech Spinout Developing Revolutionary Battery Technology: Power the Next Generation of Electronics with Carbon July 23rd, 2014

Deadline Announced for Registration in 7th Int'l Nanotechnology Festival in Iran July 23rd, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Govt.-Legislation/Regulation/Funding/Policy

NNCO Announces an Interactive Webinar: Progress Review on the Coordinated Implementation of the National Nanotechnology Initiative 2011 Environmental, Health, and Safety Research Strategy July 23rd, 2014

Nano-sized Chip "Sniffs Out" Explosives Far Better than Trained Dogs: TAU researcher's groundbreaking sensor detects miniscule concentrations of hazardous materials in the air July 23rd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level July 22nd, 2014

Nanomedicine

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

SentiMag® Now Available in Australia and New Zealand July 21st, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Announcements

Harris & Harris Group to Host Conference Call on Second-Quarter 2014 Financial Results on August 15, 2014 July 23rd, 2014

UCF Nanotech Spinout Developing Revolutionary Battery Technology: Power the Next Generation of Electronics with Carbon July 23rd, 2014

Deadline Announced for Registration in 7th Int'l Nanotechnology Festival in Iran July 23rd, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Hysitron is Awarded TWO R&D 100 Awards for Highly Innovative Technology Developments in the Areas of Extreme Environments and Biological Mechanical Property Testing July 23rd, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

EPFL Research on the use of AFM based nanoscale IR spectroscopy for the study of single amyloid molecules wins poster competition at Swiss Physics Society meeting July 22nd, 2014

Carbyne morphs when stretched: Rice University calculations show carbon-atom chain would go metal to semiconductor July 21st, 2014

Alliances/Partnerships/Distributorships

Organometallics welcomes new editor-in-chief: Paul Chirik, Ph.D. July 22nd, 2014

Haydale and Goodfellow Announce Major Distribution Agreement for Functionalised Graphene Materials July 21st, 2014

SentiMag® Now Available in Australia and New Zealand July 21st, 2014

Martini Tech Inc. becomes the exclusive distributor for Yoshioka Seiko Co. porous chucks for Europe and North America July 20th, 2014

Research partnerships

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level July 22nd, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Tiny laser sensor heightens bomb detection sensitivity July 19th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE