Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

Abstract:
Pitt joins North Carolina A&T and University of Cincinnati in $18.5 million effort to create orthopedic, craniofacial, and cardiovascular devices that adapt to a patient's anatomy and dissolve when no longer needed

A&T first historically Black college to receive prestigious Engineering Research Center grant from NSF


Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

PITTSBURGH, PA | Posted on September 5th, 2008

University of Pittsburgh researchers will help lead dozens of engineers and doctors from universities and industries around the world for a five-year, $18.5 million project announced Sept. 4 to develop implantable devices made from biodegradable metals. The devices will be designed to adapt to physical changes in a patient's body and dissolve once they have healed, reducing the follow-up surgeries and potential complications of major orthopedic, craniofacial, and cardiovascular procedures and sparing millions of patients worldwide added pain and medical expenses.

Pitt belongs to the project's central partnership along with the University of Cincinnati (UC) and the project's lead institution, North Carolina Agricultural and Technical State University (NCAT). Serving as deputy director is William Wagner, deputy director of Pitt's McGowan Institute for Regenerative Medicine and professor of surgery, bioengineering, and chemical engineering in the Swanson School of Engineering.

"The treatment of diseased and traumatized tissues is evolving as medical technologies increasingly harness the body's regenerative powers," Wagner said. "This effort will extend this approach by combining the mechanical attributes of metals with biologically active agents that together will further encourage the natural healing process."

Jagannathan Sankar, NCAT's Distinguished University Professor of mechanical engineering and director of the Center for Advanced Materials and Smart Structures, will direct the project with UC professor Mark Schulz, codirector of the UC Nanoworld and Smart Materials and Devices Laboratories, joining Wagner as deputy director.

The project stems from a five-year Engineering Research Center (ERC) grant NCAT received from the National Science Foundation (NSF) in collaboration with Pitt and UC. The highly competitive ERC grant supports large-scale university and industry collaborations on pioneering technologies. Five grants were awarded this year from 143 applicants and only 29 universities in the past 25 years have received an ERC. NCAT is the first Historically Black College and University (HCBU) to become an ERC. To coincide with the grant project, NCAT will establish the first bioengineering department at an HCBU with the assistance of faculty members in Pitt's Department of Bioengineering, McGowan Institute for Regenerative Medicine, and at UC. The department will offer bachelor's, master's, and PhD degrees.

The ERC project will focus primarily on producing three technologies: biodegradable and self-adapting devices and smart constructs for craniofacial and orthopedic reconstructive procedures, similarly behaving cardiovascular devices such as stents, and miniaturized sensing systems that monitor and control the safety and effectiveness of biodegradable metals inside the body (a technology that could lead to responsive biosensors that help doctors determine when and where diseases occur in the body).

The biodegradable devices and smart structures are intended to reduce complications and spare patients with conditions ranging from cleft palate and bone fractures to coronary heart disease from undergoing multiple surgeries. For instance, children born with a cleft palate are fitted with hard metal devices that must be removed and refitted over time. Devices the ERC researchers will explore-crafted from magnesium alloys and other biodegradable metals-would adapt to the body without refitting. Plus, magnesium alloys dissolve after their work is done with no clinical side effects, a feature also beneficial in the cardiovascular realm. Magnesium stents and other supports would restore cardiovascular function without having to remove the device and without exposing the patient to the potential complications of leaving it inside the body.

The project pools Pitt's strength in biomaterials and regenerative medicine stemming from the work conducted in the Swanson School's Departments of Bioengineering, Chemical Engineering, and Mechanical Engineering and Material Sciences, the McGowan Institute for Regenerative Medicine, and the School of Dental Medicine with NCAT's recognized expertise in metallurgy and UC's research in nano- and sensor technology.

"This project builds on two of the most important research areas in the Swanson School, bio- and mechanical engineering," said Gerald Holder, Pitt's U.S. Steel Dean of Engineering. "We are proud to be a part of the team developing the technology that will help people by improving many medical procedures. The impact on our local economy, which is highly dependent on medical-based development, will be very significant. New companies will result from the research done through this ERC, companies that will continue to conduct research, manufacture medical devices, and develop advanced procedures and technology."

Other partners include Germany's Hannover Medical School for support in medical implantology. The Indian Institute of Technology in Madras, India, will provide a global prospective on the research and application of nano- and biomaterials. California State University at Los Angeles, a designated Hispanic Serving Institution, will conduct bioscience research to help engage underrepresented students.

Nearly 30 product development and industrial partners in the nano- and biotechnology market will form a consortium with ERC to provide input for the direction of research and to help transfer ERC technology to patients.

####

For more information, please click here

Contacts:
Morgan Kelly
412-624-4356 (office)
412-897-1400 (cell)

Copyright © University of Pittsburgh

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Industrial Nanotech, Inc. Announces Next Large Order from the Oil and Gas Industry March 26th, 2015

Quantum compute this -- WSU mathematicians build code to take on toughest of cyber attacks: Revamped knapsack code offers online security for the future March 26th, 2015

Thousands of atoms entangled with a single photon: Result could make atomic clocks more accurate March 26th, 2015

Square ice filling for a graphene sandwich March 26th, 2015

Govt.-Legislation/Regulation/Funding/Policy

LAMDAMAP 2015 hosted by the University March 26th, 2015

SUNY Poly & M+W Make Major Announcement: Major Expansion To Include M+W Owned Gehrlicher Solar America Corporation That Will Create up to 400 Jobs to Develop Solar Power Plants at SUNY Poly Sites Across New York State March 26th, 2015

Thousands of atoms entangled with a single photon: Result could make atomic clocks more accurate March 26th, 2015

Carbon nanotube fibers make superior links to brain: Rice University invention provides two-way communication with neurons March 25th, 2015

Nanomedicine

Graphene reduces wear of alumina ceramic March 26th, 2015

Application of Graphene Oxide in Body Implants in Iran March 26th, 2015

Nanorobotic agents open the blood-brain barrier, offering hope for new brain treatments March 25th, 2015

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Announcements

Industrial Nanotech, Inc. Announces Next Large Order from the Oil and Gas Industry March 26th, 2015

Quantum compute this -- WSU mathematicians build code to take on toughest of cyber attacks: Revamped knapsack code offers online security for the future March 26th, 2015

Thousands of atoms entangled with a single photon: Result could make atomic clocks more accurate March 26th, 2015

Square ice filling for a graphene sandwich March 26th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

FEI Technology Award of the German Neuroscience Society Goes to Benjamin Judkewitz of the University of Berlin: Bi-annual award honors excellence in brain research during the German Neuroscience Society’s Annual Meeting, held 18-21 March 2015 March 26th, 2015

FEI Announces Image Contest Grand Prize Winner: Francisco Rangel of the National Institute of Technology, INT/MCTI, Brazil, wins the contest with his “Expanded Vermiculite” image March 23rd, 2015

Halas, Nordlander awarded Optical Society's R.W. Wood Prize: Rice University researchers recognized for pioneering nanophotonics March 21st, 2015

Hiden Instruments identified in London Stock Exchange’s ‘1000 Companies to Inspire Britain' March 21st, 2015

Alliances/Partnerships/Distributorships

NXP and GLOBALFOUNDRIES Announce Production of 40nm Embedded Non-Volatile Memory Technology: Co-developed technology to leverage GLOBALFOUNDRIES 40nm process technology platform March 24th, 2015

Young NTU Singapore spin-off clinches S$4.3 million joint venture with Chinese commercial giant March 23rd, 2015

Halas, Nordlander awarded Optical Society's R.W. Wood Prize: Rice University researchers recognized for pioneering nanophotonics March 21st, 2015

EU Funded PCATDES Project has completed its half-period with success March 19th, 2015

Research partnerships

SUNY Poly & M+W Make Major Announcement: Major Expansion To Include M+W Owned Gehrlicher Solar America Corporation That Will Create up to 400 Jobs to Develop Solar Power Plants at SUNY Poly Sites Across New York State March 26th, 2015

ORNL-led team demonstrates desalination with nanoporous graphene membrane March 25th, 2015

New kind of 'tandem' solar cell developed: Researchers combine 2 types of photovoltaic material to make a cell that harnesses more sunlight March 24th, 2015

UW scientists build a nanolaser using a single atomic sheet March 24th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE