Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

Abstract:
Pitt joins North Carolina A&T and University of Cincinnati in $18.5 million effort to create orthopedic, craniofacial, and cardiovascular devices that adapt to a patient's anatomy and dissolve when no longer needed

A&T first historically Black college to receive prestigious Engineering Research Center grant from NSF


Pitt Part of Multi-University Project That Aims to Reduce Complications, Multiple Surgeries With Biodegradable Implantable Devices

PITTSBURGH, PA | Posted on September 5th, 2008

University of Pittsburgh researchers will help lead dozens of engineers and doctors from universities and industries around the world for a five-year, $18.5 million project announced Sept. 4 to develop implantable devices made from biodegradable metals. The devices will be designed to adapt to physical changes in a patient's body and dissolve once they have healed, reducing the follow-up surgeries and potential complications of major orthopedic, craniofacial, and cardiovascular procedures and sparing millions of patients worldwide added pain and medical expenses.

Pitt belongs to the project's central partnership along with the University of Cincinnati (UC) and the project's lead institution, North Carolina Agricultural and Technical State University (NCAT). Serving as deputy director is William Wagner, deputy director of Pitt's McGowan Institute for Regenerative Medicine and professor of surgery, bioengineering, and chemical engineering in the Swanson School of Engineering.

"The treatment of diseased and traumatized tissues is evolving as medical technologies increasingly harness the body's regenerative powers," Wagner said. "This effort will extend this approach by combining the mechanical attributes of metals with biologically active agents that together will further encourage the natural healing process."

Jagannathan Sankar, NCAT's Distinguished University Professor of mechanical engineering and director of the Center for Advanced Materials and Smart Structures, will direct the project with UC professor Mark Schulz, codirector of the UC Nanoworld and Smart Materials and Devices Laboratories, joining Wagner as deputy director.

The project stems from a five-year Engineering Research Center (ERC) grant NCAT received from the National Science Foundation (NSF) in collaboration with Pitt and UC. The highly competitive ERC grant supports large-scale university and industry collaborations on pioneering technologies. Five grants were awarded this year from 143 applicants and only 29 universities in the past 25 years have received an ERC. NCAT is the first Historically Black College and University (HCBU) to become an ERC. To coincide with the grant project, NCAT will establish the first bioengineering department at an HCBU with the assistance of faculty members in Pitt's Department of Bioengineering, McGowan Institute for Regenerative Medicine, and at UC. The department will offer bachelor's, master's, and PhD degrees.

The ERC project will focus primarily on producing three technologies: biodegradable and self-adapting devices and smart constructs for craniofacial and orthopedic reconstructive procedures, similarly behaving cardiovascular devices such as stents, and miniaturized sensing systems that monitor and control the safety and effectiveness of biodegradable metals inside the body (a technology that could lead to responsive biosensors that help doctors determine when and where diseases occur in the body).

The biodegradable devices and smart structures are intended to reduce complications and spare patients with conditions ranging from cleft palate and bone fractures to coronary heart disease from undergoing multiple surgeries. For instance, children born with a cleft palate are fitted with hard metal devices that must be removed and refitted over time. Devices the ERC researchers will explore-crafted from magnesium alloys and other biodegradable metals-would adapt to the body without refitting. Plus, magnesium alloys dissolve after their work is done with no clinical side effects, a feature also beneficial in the cardiovascular realm. Magnesium stents and other supports would restore cardiovascular function without having to remove the device and without exposing the patient to the potential complications of leaving it inside the body.

The project pools Pitt's strength in biomaterials and regenerative medicine stemming from the work conducted in the Swanson School's Departments of Bioengineering, Chemical Engineering, and Mechanical Engineering and Material Sciences, the McGowan Institute for Regenerative Medicine, and the School of Dental Medicine with NCAT's recognized expertise in metallurgy and UC's research in nano- and sensor technology.

"This project builds on two of the most important research areas in the Swanson School, bio- and mechanical engineering," said Gerald Holder, Pitt's U.S. Steel Dean of Engineering. "We are proud to be a part of the team developing the technology that will help people by improving many medical procedures. The impact on our local economy, which is highly dependent on medical-based development, will be very significant. New companies will result from the research done through this ERC, companies that will continue to conduct research, manufacture medical devices, and develop advanced procedures and technology."

Other partners include Germany's Hannover Medical School for support in medical implantology. The Indian Institute of Technology in Madras, India, will provide a global prospective on the research and application of nano- and biomaterials. California State University at Los Angeles, a designated Hispanic Serving Institution, will conduct bioscience research to help engage underrepresented students.

Nearly 30 product development and industrial partners in the nano- and biotechnology market will form a consortium with ERC to provide input for the direction of research and to help transfer ERC technology to patients.

####

For more information, please click here

Contacts:
Morgan Kelly
412-624-4356 (office)
412-897-1400 (cell)

Copyright © University of Pittsburgh

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Oxford Instruments’ TritonTMXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Visible Light-Sensitive Photocatalysts Used for Purification of Contaminated Water in Iran June 30th, 2015

June 29th, 2015

Govt.-Legislation/Regulation/Funding/Policy

X-rays and electrons join forces to map catalytic reactions in real-time: New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions June 29th, 2015

Graphene breakthrough as Bosch creates magnetic sensor 100 times more sensitive than silicon equivalent June 28th, 2015

Helium 'balloons' offer new path to control complex materials June 27th, 2015

The peaks and valleys of silicon: Team of USC Viterbi School of Engineering Researchers introduce new layered semiconducting materials as silicon alternative June 27th, 2015

Nanomedicine

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Efforts to Use Smart Nanocarriers to Cure Leukemia Yield Promising Results June 29th, 2015

Chivalrous Knight Does Pro Bono June 27th, 2015

Green Chemistry Methods Used in Iran to Produce Zinc Oxide Nanoparticles June 27th, 2015

Announcements

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Oxford Instruments’ TritonTMXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Visible Light-Sensitive Photocatalysts Used for Purification of Contaminated Water in Iran June 30th, 2015

Making new materials with micro-explosions: ANU media release: Scientists have made exotic new materials by creating laser-induced micro-explosions in silicon, the common computer chip material June 29th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

World’s 1st Full-Color, Flexible, Skin-Like Display Developed at UCF June 24th, 2015

Physicists fine-tune control of agile exotic materials: Tunable hybrid polaritons realized with graphene layer on hexagonal boron nitride June 24th, 2015

Robust new process forms 3-D shapes from flat sheets of graphene June 23rd, 2015

Lancaster University revolutionary quantum technology research receives funding boost June 22nd, 2015

Alliances/Trade associations/Partnerships/Distributorships

Graphene breakthrough as Bosch creates magnetic sensor 100 times more sensitive than silicon equivalent June 28th, 2015

Dyesol Joins Solliance as an Industrial Partner June 17th, 2015

Framework materials yield to pressure June 11th, 2015

The European project SVARNISH, a step forward in the food packaging sector June 11th, 2015

Research partnerships

June 29th, 2015

Graphene breakthrough as Bosch creates magnetic sensor 100 times more sensitive than silicon equivalent June 28th, 2015

The peaks and valleys of silicon: Team of USC Viterbi School of Engineering Researchers introduce new layered semiconducting materials as silicon alternative June 27th, 2015

Building a better semiconductor: Research led by Michigan State University could someday lead to the development of new and improved semiconductors June 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project