Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Particle Sciences Develops Zero-Order-Release Combination Device Technology

Abstract:
Particle Sciences Inc. today announced the development of their "Microreservoir" technology enabling the manufacture of drug-eluting polymer medical devices that release drugs at constant rates over 30 days or more. This technology has already been used by Particles Sciences to develop drug eluting vaginal rings. "Drug release from polymeric materials often follows a burst/first-order kinetic profile which may not be clinically desired," explained Andrew Loxley, Director of New Technologies. "Traditionally the burst effect has been reduced by confining the API to a reservoir within the device, but this adds complexity and cost to production," he added. In their approach, Particle Sciences' scientists first encapsulate the drug in polymer microparticles before blending with the polymer used to make the final product. Robert Lee, VP of Pharmaceutical Development commented, "Microencapsulating the drug enabled the use of simple molding processes to fabricate devices containing tens of thousands of 'microreservoirs,' and the devices exhibit constant drug release profiles equivalent to traditional reservoir devices. This approach greatly simplifies production and adds tremendous flexibility to both single and multi-drug devices." Particle Sciences sees broad utility for this proprietary technology, which is applicable to polymer devices, films, coatings and other polymeric structures from which drugs or other materials are to be released at a constant rate.

Particle Sciences Develops Zero-Order-Release Combination Device Technology

BETHLEHEM, PA | Posted on August 27th, 2008

####

About Particle Sciences Inc.
Particle Sciences is an integrated provider of drug development services. Particle Sciences focuses on emulsions, gels, particulates and drug/device combination products with additional specialized capabilities in topical and mucosal drug delivery. Through a full range of formulation, analytic, and manufacturing services, Particle Sciences provides pharmaceutical companies with a complete and seamless development solution that minimizes the time and risk between discovery and the clinic. The company was founded in 1991 and is headquartered in Bethlehem, Pennsylvania.

For more information, please click here

Contacts:
Maureen Cochran
610-861-4701

Copyright © PR Newswire Association LLC.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Nanometrics to Participate in the 6th Annual NYC Investor Summit 2017 November 16th, 2017

Nanomedicine

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3ís significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Arrowhead to Present at 29th Annual Piper Jaffray Healthcare Conference November 14th, 2017

A new way to mix oil and water: Condensation-based method developed at MIT could create stable nanoscale emulsions November 8th, 2017

Nanoshells could deliver more chemo with fewer side effects: In vitro study verifies method for remotely triggering release of cancer drugs November 8th, 2017

Announcements

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Nanometrics to Participate in the 6th Annual NYC Investor Summit 2017 November 16th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project