Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Zetasizer Nano contributes to drug carrier research at UK’s newest School of Pharmacy

Abstract:
Nanoparticle characterization using the Zetasizer Nano from Malvern Instruments is providing essential information for researchers working on drug delivery systems at the UK's newest School of Pharmacy and Pharmaceutical Sciences. The new school, which opened in September 2007, is part of the University of Central Lancashire.

Zetasizer Nano contributes to drug carrier research at UK’s newest School of Pharmacy

Malvern, UK | Posted on June 25th, 2008

Nanoparticle characterization using the Zetasizer Nano from Malvern Instruments is providing essential information for researchers working on drug delivery systems at the UK's newest School of Pharmacy and Pharmaceutical Sciences. The new school, which opened in September 2007, is part of the University of Central Lancashire. It is developing a multi-disciplinary approach to research, focusing on important areas of pharmaceutical sciences and practice. One such is pharmaceutics and pharmaceutical analysis where research teams are working with a range of colloidal systems for drug delivery, including microspheres, aerosols and dendrimers.

Prof. Antony D'Emanuele, Chair in Pharmaceutics and Head of the School, leads the Dendrimer Group, whose work centres on the development of nanocarriers for a number of pharmaceutical and biomedical applications. Dendrimers are well-defined and effectively monodisperse, highly branched molecules possessing an architecture that allows control over properties such as shape, size, density, polarity, reactivity and solubility. Their surface groups are amenable to modification and can be tailored for specific applications.

"As part of our work we are developing a range of nanocarriers for oral drug delivery," said Prof. D'Emanuele. "It is here that the Zetasizer Nano has proved especially useful in allowing us to characterize surface engineered dendrimers intended for this purpose. We are able to monitor changes in size as we modify the surface of our dendrimers and also determine whether our carriers aggregate."

The Zetasizer Nano simplifies the automated measurement of particle size, stability characterization using zeta potential, and molecular weight, for a wide range of dispersions, emulsions and molecules in solution. Sensitive enough for the measurement of solutions of proteins and polymers, yet able to measure at high concentrations, it is now the method of choice for nano-particle applications from routine colloid size measurement to the investigation of particulates at the leading edge of materials research.

Particle size measurement is in the range 0.6 to 6000 nm, molecular weight measurement from 1 x 103 to 2 x 107 Daltons, and zeta potential of particles from 5 nm to 10 µm.

The new School has a suite of particle sizing equipment which also includes Malvern Spraytec and Mastersizer systems.www.malvern.com

Malvern, Malvern Instruments, Zetasizer and Mastersizer are registered trademarks of Malvern Instruments Ltd Spraytec is a trademark of Malvern Instruments Ltd

High resolution image attached or available from Trish Appleton, Kapler Communications Ref: MAL/JOB/1420

####

About Malvern Instruments
Malvern Instruments provides a range of complementary materials characterization tools that deliver inter-related measurements reflecting the complexities of particulates and disperse systems, nanomaterials and macromolecules. Analytical instruments from Malvern are used in the characterization of a wide variety of materials, from industrial bulk powders to the latest nanomaterials and delicate macromolecules. A broad portfolio of innovative technologies is combined with intelligent, user-friendly software. These systems deliver industrially relevant data enabling our customers to make the connection between micro (such as particle size) and macro (bulk) material properties (rheology) and chemical composition (chemical imaging).

Particle size distribution, particle shape information, zeta potential, molecular weight, chemical composition, and bulk materials properties can all be determined with instruments from the Malvern range. The company’s laboratory, at-line, on-line and in-line solutions are proven in sectors as diverse as cement production and pharmaceutical drug discovery.

Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Korea and Japan, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com

Contacts:
Trish Appleton
Kapler Communications
Knowledge Centre
Wyboston Lakes
Great North Road,
Wyboston
Bedfordshire
MK44 3BY
UK
T: +44 (0)1480 479280;
F: +44 (0)1480 470343



USA contact:
Marisa Fraser
Malvern Instruments Inc
117 Flanders Road
Westborough
MA 01581-1042
USA
Tel: +1 508 768 6400
Fax: +1 508 768 6403

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Stanford team achieves 'holy grail' of battery design: A stable lithium anode - Engineers use carbon nanospheres to protect lithium from the reactive and expansive problems that have restricted its use as an anode July 27th, 2014

Iranian Scientists Produce Reusable Nanoadsorbent to Detect Sulfamide in Chicken July 27th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Nanomedicine

New imaging agent provides better picture of the gut July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Announcements

Stanford team achieves 'holy grail' of battery design: A stable lithium anode - Engineers use carbon nanospheres to protect lithium from the reactive and expansive problems that have restricted its use as an anode July 27th, 2014

Iranian Scientists Produce Reusable Nanoadsorbent to Detect Sulfamide in Chicken July 27th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Tools

Malvern Instruments completes acquisition of MicroCal and announces purchase of Archimedes product from Affinity Biosensors July 25th, 2014

Hysitron is Awarded TWO R&D 100 Awards for Highly Innovative Technology Developments in the Areas of Extreme Environments and Biological Mechanical Property Testing July 23rd, 2014

The Hiden EQP Plasma Diagnostic with on-board MCA July 22nd, 2014

Nanometrics Announces Upcoming Investor Events July 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE