Home > News > Cell 'organs' get plastic upgrades
June 6th, 2008
Cell 'organs' get plastic upgrades
Abstract:
Human cells could have their metabolisms upgraded without altering their genes by inserting tiny plastic packages of enzymes, Swiss researchers have shown. They hope the technique could allow advanced cancer therapies, or even upgrade a person's metabolism.
The cells of multi-cellular organisms and some advanced single-celled organisms have internal compartments called organelles to carry out specialised metabolic functions. Researchers at University of Basel, Switzerland, used artificial polymer organelles to upgrade live human cells in a lab dish.
Meier and colleagues coated their polymer vesicles in a chemical that encouraged human white blood cells called macrophages to engulf them. The small capsules contained enzymes, just like natural organelles. The enzymes chosen produced fluorescent chemicals, signalling they were working without problems inside their new host.
The artificial organelle's membrane can be chemically tuned to control which chemicals can pass through it and regulate the reactions inside, according to Wolfgang Meier, one of the researchers. "We call it a 'nanoreactor'," he says.
At 200 nanometres across, the organelles are 400 times smaller in width than a human hair.
Source:
technology.newscientist.com
Bookmark:
News and information
Aspen Aerogels Announces $22.5 Million Private Placement May 18th, 2013
NanoInk, Inc. Assets To Be Sold May 18th, 2013
Beautiful "flowers" self-assemble in a beaker: Elaborate nanostructures blossom from a chemical reaction perfected at Harvard May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013
Nanomedicine
Nanotechnology could help fight diabetes: Injectable nanogel can monitor blood-sugar levels and secrete insulin when needed May 16th, 2013
Nanobiotix Revenue for the 1st quarter of 2013 May 15th, 2013
Pitt Chemists Demonstrate Nanoscale Alloys So Bright They Could Have Potential Medical Applications: “Think about a particle that will not only help researchers detect cancer sooner but be used to treat the tumor, too.” May 15th, 2013
Using clay to grow bone: Researchers use synthetic silicate to stimulate stem cells into bone cells May 15th, 2013
Discoveries
Beautiful "flowers" self-assemble in a beaker: Elaborate nanostructures blossom from a chemical reaction perfected at Harvard May 17th, 2013
Artificial Forest for Solar Water-Splitting: Berkeley Lab Researchers Report First Fully Integrated Artificial Photosynthesis Nanosystem May 17th, 2013
Moth-Inspired Nanostructures Take the Color Out of Thin Films May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013
Announcements
Aspen Aerogels Announces $22.5 Million Private Placement May 18th, 2013
NanoInk, Inc. Assets To Be Sold May 18th, 2013
NIA Public Briefing: Nanotechnology and the Council of Europe May 17th, 2013
Scientists capture first direct proof of Hofstadter butterfly effect May 17th, 2013