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May 23rd, 2008
Researchers at North Carolina State University say that lab experiments with gold nanoparticles have shown that it may be possible to resurrect a failed HIV drug called TAK779, ruled out as a useful therapy in the early Nineties due to its severe side effects, using them.
The researchers say that an ammonium salt in the drug was the main cause of harmful side effects, and that reducing it was just not possible because it would render the drug useless against HIV by disabling the resulting molecule to bind to the virus tightly.
Now, they insist, their study has shown some promise in improving the efficacy of the drug (without in binding the ammonium salt) in binding to HIV by combining it with gold nanoparticles.
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