Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Ulster Scientists Develop DNA Biosensor Technology

Scientists Dr Tony Byrne, Professor Pascal Mailley and Dr Patrick Lemoine are collaborating on developing ground-breaking biosensors
Scientists Dr Tony Byrne, Professor Pascal Mailley and Dr Patrick Lemoine are collaborating on developing ground-breaking biosensors

Abstract:
Scientists at the University of Ulster are using nanotechnology - highly miniaturised technology - to build new DNA biosensors which could be used in identifying genetic diseases, cancer research, identification of dangerous micro-organisms, and forensic science.

Ulster Scientists Develop DNA Biosensor Technology

Belfast, Ireland | Posted on May 21st, 2008

Dr Patrick Lemoine and Dr Tony Byrne from the School of Electrical and Mechanical Engineering at Ulster have teamed up with French biosensor expert, Professor Pascal Mailley from the CEA Grenoble research facility for the project.

The collaboration has been facilitated by a research grant from the Royal Society.

The aim of the project is to devise a DNA biosensor using new nanoscale fabrication techniques. This means manipulating engineering materials which are one thousand times smaller than the width of a human hair.

The Nanotechnology and Integrated BioEngineering Centre (NIBEC) at Ulster has state-of-the-art facilities for nanomaterials research as well as the mix of disciplinary expertise - physics, chemistry, biology and engineering, required for such projects.

Man-made biosensors are usually small hand-held devices costing a few pounds, which can replace laboratory systems costing thousands of pounds. Some are already commercially available in pharmacies, such as blood/sugar measurement devices essential for diabetics.

What is not available is an equivalent biosensor to detect DNA - the long chain molecule hidden in human cells which holds the key to life and which provides an unique code for every individual on earth.

Such a biosensor would present enormous opportunities. For example, DNA sequencing is necessary for the identification and treatment of genetic diseases, for cancer research, for the identification of dangerous micro-organisms or for forensic science."

Dr Lemoine says: "The key idea of the proposal is to use specific techniques called ‘self-assembly' and ‘nano-patterning' to create arrays containing millions of pixels with very high surface areas.

This means that more DNA fragments can be immobilised in smaller geometric areas, typically a few millimetres square. When the ‘chip' is exposed to a sample of unknown DNA, the complementary strands join up, revealing the sequence of the unknown DNA.

This technology is not only applicable to DNA chips but might allow the production of biosensors using a wide range of bio-molecules which may be used as miniature implantable sensors for monitoring conditions within the body.

For example, the development of an artificial pancreas, which could both measure glucose and control insulin delivery, would be of major benefit to diabetics.

####

About Nanotechnology and Integrated BioEngineering Centre
NIBEC - the Nanotechnology and Integrated BioEngineering Centre is a well established world-class research complex at the University of Ulster's Jordanstown campus. NIBEC represents a consolidation of eight advanced functional materials research groups, dealing with thin-film material types used in electronics, photonics, nanotechnology, sensors, MEMS, optical, environmental, magnetic and bio-material devices.

The £10M purpose-built facilities house some of the most sophisticated nano-fabrication, biological and characterisation equipment in the world. Strong international collaborations have been developed and large infrastructural and project funding has been a highlight of this rapidly growing research area. The centre hosts major core research initiatives such as MATCH (EPSRC National Centre); CACR (UU and Royal Victoria Hospital); NanotecNI (UU and QUB); and also the team have developed formal collaborations with numerous world-wide Institutions and Industry.

NIBEC is staffed by an internationally recognised team of researchers and academics working predominantly at the interface of bioengineering and nanotechnology. Technology transfer is a key objective and a number of successful spin-out companies have emerged from NIBEC in recent years, the most successful of these being Heartscape, HeartSine Technology and Sensors Technology and Devices Ltd (ST&D).

For more information, please click here

Contacts:
Press Office
Communication and Development
Tel:(028) 9036 6178
Email:

Copyright © University of Ulster

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Nanomedicine

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Nanion Technologies Appoints James Costantin as Director of Customer Relations: Nanion is pleased to announce the appointment of Dr. James Costantin as Director of Customer Relations at Nanion Technologies Inc. March 31st, 2015

Nanomedicine shines light on combined force of nanomedicine and regenerative medicine March 31st, 2015

Prototype 'nanoneedles' generate new blood vessels in mice: Scientists have developed tiny 'nanoneedles' that have successfully prompted parts of the body to generate new blood vessels, in a trial in mice March 31st, 2015

Sensors

From tobacco to cyberwood March 31st, 2015

UW scientists build a nanolaser using a single atomic sheet March 24th, 2015

Iranian Researchers Present Model to Determine Dynamic Behavior of Nanostructures March 24th, 2015

Nanodevice Invented in Iran to Detect Hydrogen Sulfide in Oil, Gas Industry March 20th, 2015

Discoveries

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Light-powered gyroscope is world's smallest: Promises a powerful spin on navigation April 1st, 2015

Announcements

Quantum teleportation on a chip: A significant step towards ultra-high speed quantum computers April 1st, 2015

So, near and yet so far: Stable HGNs for Raman April 1st, 2015

Two-dimensional dirac materials: Structure, properties, and rarity April 1st, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

Nanobiotechnology

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels April 1st, 2015

From tobacco to cyberwood March 31st, 2015

Wrapping carbon nanotubes in polymers enhances their performance: Scientists at Japan's Kyushu University say polymer-wrapped carbon nanotubes hold much promise in biotechnology and energy applications March 30th, 2015

'Atomic chicken-wire' is key to faster DNA sequencing March 30th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE