Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > UCF Technique Promises to Aid Doctors' Ability to Identify, Treat Bacterial Infections

Photo: Jacque Brund.

Nanoscience Technology Center post-doctoral fellow Sudip Nath and graduate student Charalambos Kaittanis are co-authors of the study published in Analytical Chemistry.
Photo: Jacque Brund.
Nanoscience Technology Center post-doctoral fellow Sudip Nath and graduate student Charalambos Kaittanis are co-authors of the study published in Analytical Chemistry.

Abstract:
A new technique developed by a University of Central Florida chemist will help physicians more quickly identify the bacterial infections patients have so they can be treated in hours instead of days.

UCF Technique Promises to Aid Doctors' Ability to Identify, Treat Bacterial Infections

Orlando, FL | Posted on February 20th, 2008

As more bacterial strains resistant to many drugs emerge, it becomes more critical to quickly identify infections and the antibiotics that would most effectively treat them. Such quick identifications become even more important during epidemics because large numbers of samples would have to be tested at once.

Assistant Professor J. Manuel Perez's new technique also promises to give research institutes and pharmaceutical companies a quicker and cheaper way of developing new antibiotics to combat super bugs.

The results of Perez's study were recently published online in Analytical Chemistry (pubs.acs.org/cgi-bin/asap.cgi/ancham/asap/pdf/ac701969u.pdf). The research was funded in part by the National Institutes of Health.

"The method really gives doctors quicker access to test results so they can treat their patients more quickly," Perez said from his lab at the Nanoscience Technology Center at UCF. "But there are more applications. This method can also be used by research facilities and big pharmaceutical companies for the high throughput screening of drugs for antibacterial activity."

Perez uses gold nanoparticles coated with a sugar and a protein that binds to sugars. Meanwhile, a variety of antibiotics are placed in the same solution. A spectrophotometer reads optical variations in the gold nanoparticle solution as the sugar and protein shift , which in turn demonstrate which antibiotics effectively halt bacteria growth and which ones do not. Results can be obtained within a couple of hours, in contrast to the traditional methods, which can take days to complete. And hundreds of samples can be tested at once using this technique because the amount of bacteria and antibiotic needed is small.

Pharmaceutical companies can use existing equipment to read the variations, which means they do not have to buy new equipment. Perez's study also shows that the technique is as sensitive and accurate as the traditional, more time-consuming approach.

"We're very excited and very pleased with the results," Perez said.

The research was completed with the help of the UCF Chemistry Department and the Burnett School of Biomedical Sciences. Nanoscience Technology Center post-doctoral fellow Sudip Nath and graduate student Charalambos Kaittanis are co-authors of the study, as is Alisa Tinkham, formerly of the Burnett School.

####

About University of Central Florida
UCF Stands for Opportunity -- Established in 1963, the University of Central Florida is a diverse metropolitan research university that ranks as the 6th-largest in the country with more than 48,000 students. Located in Orlando, Fla., UCF offers high-quality undergraduate and graduate education, student development, and continuing education, while conducting cutting-edge research that powers the region’s economic development. For more UCF news, visit news.ucf.edu.

For more information, please click here

Contacts:
Zenaida Gonzalez Kotala
News and Information
407-823-6120

Copyright © University of Central Florida

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

JPK’s NanoWizard AFM system is being used for cell studies in the Research Centre for Nanometer-scale Science & Advanced Materials at the Jagiellonian University in Krakow, Poland May 31st, 2016

Nanobiotix receives US$1m milestone payment from PharmaEngine: First patient injected with NBTXR3 in soft tissue sarcoma registration phase in Asia May 31st, 2016

GLOBALFOUNDRIES to Expand Presence in China with 300mm Fab in Chongqing: Company plans new manufacturing facility and additional design capabilities to serve customers in China May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

Nanomedicine

JPK’s NanoWizard AFM system is being used for cell studies in the Research Centre for Nanometer-scale Science & Advanced Materials at the Jagiellonian University in Krakow, Poland May 31st, 2016

Nanobiotix receives US$1m milestone payment from PharmaEngine: First patient injected with NBTXR3 in soft tissue sarcoma registration phase in Asia May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Discoveries

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Announcements

JPK’s NanoWizard AFM system is being used for cell studies in the Research Centre for Nanometer-scale Science & Advanced Materials at the Jagiellonian University in Krakow, Poland May 31st, 2016

Nanobiotix receives US$1m milestone payment from PharmaEngine: First patient injected with NBTXR3 in soft tissue sarcoma registration phase in Asia May 31st, 2016

GLOBALFOUNDRIES to Expand Presence in China with 300mm Fab in Chongqing: Company plans new manufacturing facility and additional design capabilities to serve customers in China May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic