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February 19th, 2008
UK team to use nanoparticles to improve brain drug delivery
Abstract:
A nanoparticle-based delivery system is being developed in the UK as a potential means of bypassing the blood brain barrier and improve the treatment of central nervous system diseases such as brain cancer.
Since it first began to emerge in the late 1970s, nanotechnology has been hailed as the next step in fields as disparate as water treatment and mechanical engineering. While in general the development of such technology has been slow, in medicine the ability to create and manipulate nanoscale particles is beginning to revolutionize the production and delivery of drugs, particularly in terms of targeted therapeutics.
One example of such work is research being conducted by scientists at the University of Portsmouth, in the UK. The three-year project, which is funded by a £451,000 ($880,000) grant from the Biotechnology and Biological Sciences Research Council, is using polymer-based nanoparticles to modify a naturally occurring peptide capable of creating temporary openings in the blood-brain barrier, allowing for improved drug delivery.
Source:
in-pharmatechnologist.com
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