Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > New sensor system improves detection of lead, heavy metals

PNNL scientist Wassana Yantasee demonstrates the compact and field-portable biomonitoring device (foreground), which produces rapid, accurate results equivalent to state-of-the-art mass spectrometry systems (back) from small fluid samples.
PNNL scientist Wassana Yantasee demonstrates the compact and field-portable biomonitoring device (foreground), which produces rapid, accurate results equivalent to state-of-the-art mass spectrometry systems (back) from small fluid samples.

Abstract:
PNNL develops inexpensive portable detection system for rapid, accurate analysis of toxic metals

New sensor system improves detection of lead, heavy metals

Richland, WA | Posted on February 13th, 2008

The Department of Energy's Pacific Northwest National Laboratory has developed a new rapid, portable and inexpensive detection system that identifies personal exposures to toxic lead and other dangerous heavy metals. The device can provide an accurate blood sample measurement from a simple finger prick, which is particularly important when sampling children.

PNNL's portable analyzer system accurately detects lead and other toxic metals in blood as well as in urine and saliva. Results are as reliable as those of current state-of-the-art mass spectrometry systems many times its size. This new system provides a quicker, simpler and easier method of monitoring toxic metal exposures in high-risk populations, such as industrial workers, children and people living in polluted areas.

A bit larger than a lunchbox, the new detection system is field-deployable with plug-and-play features that allow different sensors to be easily exchanged to detect a variety of heavy metal toxins. The entire system is battery-operated and requires about one and one-half times the power of a typical laptop computer. The system also routinely delivers reliable measurements within a rapid two-to-five minute analysis period.

Early production cost estimates indicate that the device may be as much as 10 times less expensive than existing plasma mass spectrometry systems, which lack field portability and require samples to be returned to the lab for time-consuming and more expensive analysis.

Accumulation of lead in children can harm the developing brain, causing reduced IQ, learning disabilities and behavioral problems, among other things. The Centers for Disease Control and Prevention report that about 310,000 U.S. children ages 1 to 5 have high levels of lead in their blood. Recent studies also indicate a link between lead exposure and a decline in mental ability many years later.

Recent attention to children's exposure to lead from toys and products from the Far East has heightened the interest in toxic exposures to heavy metals. The ability to quickly and accurately identify children with elevated blood lead levels is important in providing treatment to those who need it. In addition, large numbers of industrial workers may be routinely exposed to toxic heavy metals like cadmium, lead and mercury, which are known to induce various diseases.

"We need next-generation analyzers to reduce the time and lower the costs of analysis for clinical diagnosis," said PNNL scientist and principal investigator Wassana Yantasee. "They will help us better understand the relationship between the exposure to these toxins and how the body responds, which will help in developing new strategies to reduce exposures and risks."

"Our research has focused on optimizing the sensor systems to work with the biological complexities in blood, urine and saliva samples," said Yantasee. "Validation of these sensor platforms for use in biomonitoring is particularly important in developing a personalized exposure assessment strategy."

The device can use two classes of sensors for detecting lead and other heavy metals. The first is based on a flow injection system using a mercury-film electrode to analyze metals in blood, urine or saliva samples.

To eliminate the use of toxic mercury in conducting the analysis, the second class of the sensor uses a mercury-free approach of nanostructure materials developed at PNNL. This involves use of either Self-Assembled Monolayers on Mesoporous Supports - SAMMS™ technology - or functionalized magnetic nanoparticles that provide excellent detection sensitivity at a parts-per-billion level.

PNNL's research is supported by extramural grants from the CDC's National Institute of Occupational Safety and Health, and the National Institutes of Health's National Institute of Environmental Health Sciences.

Battelle, which operates PNNL for DOE, filed a patent application in December 2007 for the improved sensor technology used in this next-generation biomonitoring device. Battelle is seeking commercialization partners and welcomes companies interested in the technology to contact Commercialization Manager Bruce Harrer or access Portable Electrochemical Sensing System for more information.

####

About Pacific Northwest National Laboratory
PNNL is a DOE Office of Science national laboratory that solves complex problems in energy, national security and the environment, and advances scientific frontiers in the chemical, biological, materials, environmental and computational sciences. PNNL employs 4,000 staff, has a $760 million annual budget, and has been managed by Ohio-based Battelle since the lab's inception in 1965.

Some of this research was conducted at the William R. Wiley Environmental Molecular Sciences Laboratory in Richland, Wash. EMSL is a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory.

For more information, please click here

Contacts:
Geoffrey Harvey
PNNL
(509) 372-6083

Copyright © Pacific Northwest National Laboratory

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Laboratories

Ames Laboratory, UConn discover superconductor with bounce October 25th, 2017

Nanotube fiber antennas as capable as copper: Rice University researchers show their flexible fibers work well but weigh much less October 23rd, 2017

Spin current detection in quantum materials unlocks potential for alternative electronics October 15th, 2017

Injecting electrons jolts 2-D structure into new atomic pattern: Berkeley Lab study is first to show potential of energy-efficient next-gen electronic memory October 13th, 2017

Sensors

The stacked color sensor: True colors meet minimization November 16th, 2017

Promising sensors for submarines, mines and spacecraft: MSU scientists are developing nanostructured gas sensors that would work at room temperature November 10th, 2017

Practical superconducting nanowire single photon detector with record detection efficiency over 90 percent November 9th, 2017

Dendritic fibrous nanosilica: all-in-one nanomaterial for energy, environment and health November 4th, 2017

Announcements

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Tools

Nanometrics to Participate in the 6th Annual NYC Investor Summit 2017 November 16th, 2017

Nanometrics Announces $50 Million Share Repurchase Program November 15th, 2017

Nanometrics Board of Directors Names Pierre-Yves Lesaicherre President and CEO November 14th, 2017

Oxford Instruments announces winner of the 2017 Sir Martin Wood Prize for Japan November 14th, 2017

Patents/IP/Tech Transfer/Licensing

Picosun’s ALD nanolaminates improve lifetime and reliability of electronic circuit boards October 24th, 2017

Novel 'converter' heralds breakthrough in ultra-fast data processing at nanoscale: Invention bagged four patents and could potentially make microprocessor chips work 1,000 times faster October 20th, 2017

Nanoparticles limit damage in spinal cord injury: Injection after an injury reduces inflammation and scarring September 6th, 2017

More durable, less expensive fuel cells: University of Delaware researchers have developed a new technology that could speed up the commercialization of fuel cell vehicles September 5th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project