Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Monash pioneers nano scaffold to rebuild nerve damage

Abstract:
A Monash University PhD student has developed a new technique that could revolutionise stem cell treatment for Parkinson's disease and spinal cord injury.

Monash pioneers nano scaffold to rebuild nerve damage

Australia | Posted on January 31st, 2008

David Nisbet from Monash University's Department of Materials Engineering has used existing polymer-based biodegradable fibres, 100 times smaller than a human hair, and re-engineered them to create a unique 3-D scaffold that could potentially allow stem cells to repair damaged nerves in the human body more quickly and effectively.

Mr Nisbet said a combined process of electrospinning and chemical treatment was used to customise the fibre structure, which can then be located within the body.

"The scaffold is injected into the body at the site requiring nerve regeneration. We can embed the stem cells into the scaffold outside the body or once the scaffold is implanted. The nerve cells adhere to the scaffold in the same way ivy grips and weaves through a trellis, forming a bridge in the brain or spinal cord. Over time, the scaffold breaks down and is naturally passed from the body, leaving the newly regenerated nerves intact," Mr Nisbet said.

Mr Nisbet said the existing processes released stem cells into the nervous system where they 'floated' around.

"Our studies show that stem cells anchored to a scaffold not only attach more easily, but rapidly adapt to their environment and regenerate effectively. We are very excited about the therapeutic outcomes that could be obtained from our research," Mr Nisbet said.

"We are at the interface of two once separate disciplines -- nanotechnology and stem cell research -- combining into a new exciting era of discovery which could be the first step towards a cure for conditions such as Parkinson's disease and spinal cord injury.

"Repairing damaged neural pathways is the holy grail of many researchers. It is a very long road to success, which will require small steps from many people, but it's wonderful to know we're making such a significant contribution here at Monash University," Mr Nisbet said.

The potential of Nisbet's scaffold design has captured the interest of colleagues. The University of Toronto in Canada and the Melbourne-based Howard Florey Institute are conducting further tests, with preliminary results showing strong potential.

Another collaboration, with the Mental Health Research Institute of Victoria, is investigating the use of scaffolds in the potential treatment of damaged brain nerve cells.

Mr Nisbet said biodegradable fibres were commonly used in biomedical sciences and regenerative technologies, but his technique of re-engineering them into a 3-D structure is a world first.

For high magnification images of the cellular structure or a copy of Mr Nisbet's paper contact Ms Samantha Blair, at +61 3 9903 4841.

####

About Monash University
Monash University seeks to improve the human condition by advancing knowledge and fostering creativity. It does so through research and education and a commitment to social justice, human rights and a sustainable environment.

For more information, please click here

Contacts:
Media Communications
Tel: +61 3 9903 4840
or +61 3 9903 4837
Email:

Copyright © Monash University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

Nanomedicine

Nanofiber scaffolds demonstrate new features in the behavior of stem and cancer cells August 25th, 2016

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer August 25th, 2016

50 years after the release of the film 'Fantastic Voyage,' science upstages fiction: Science upstages fiction with nanorobotic agents designed to travel in the human body to treat cancer August 25th, 2016

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

Discoveries

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

Nanofur for oil spill cleanup: Materials researchers learn from aquatic ferns: Hairy plant leaves are highly oil-absorbing / publication in bioinspiration & biomimetics / video on absorption capacity August 25th, 2016

Unraveling the crystal structure of a -70 Celsius superconductor, a world first: Significant advancement in the realization of room-temperature superconductors August 25th, 2016

Announcements

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic