Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Cancer study shows power of interdisciplinary approach

Abstract:
A UCLA cancer study reported in this month's Nature Nanotechnology validates earlier work by MIT engineers, and is emblematic of an explosion in research at the intersections of engineering, the life sciences and medicine, according to MIT Dean of Engineering Subra Suresh.

Cancer study shows power of interdisciplinary approach

CAMBRIDGE, MA | Posted on December 3rd, 2007

Since about 2002, Suresh and colleagues have applied state-of-the-art techniques for the study of nanoscale mechanical properties of materials to the study of the physical characteristics of living cells, with a particular emphasis on infectious diseases and cancer. In several papers over the past three years, they have shown that metastatic, or spreading, pancreatic cancer cells are significantly softer (less stiff) than their benign and nonmetastatic counterparts. The results paved the way for a potential new diagnostic test for the disease.

The UCLA work takes the research an important step further. Those researchers, led by James K. Gimzewski, analyzed live cancer cells taken from body cavity fluids from the lung, breast and pancreas of patients with suspected metastatic cancer. Among other things, fluid samples contain both benign and metastatic cells for direct comparison.

Using biomechanical techniques similar to those of the Suresh team, Gimzewski and colleagues found that cancer cells were nearly four times softer than their benign counterparts from the same fluid sample.

Suresh, who wrote an accompanying commentary to the UCLA paper in Nature Nanotechnology, describes such a nanomechanical approach as a potentially powerful means for detecting cancer along with other tools currently used for diagnosis.

"This is a good example of an intersection of engineering with life sciences and medical practice," Suresh, who is also the Ford Professor of Engineering, told the News Office in an interview. "We've brought tools that the medical community is not generally aware of to probe a human disease, in this case cancer."

The UCLA and MIT work toward a potential new diagnostic method for cancer is just one example of what can be achieved when engineers and scientists work together on the study of human diseases, Suresh said, adding that such collaborations between engineers and researchers in the life sciences are part of a rapidly growing trend.

As an example, he cited MIT's recent announcement of plans to build the David H. Koch Institute for Integrative Cancer Research, which will bring together scientists and engineers under one roof to develop new and powerful ways to detect, diagnose, treat and manage cancer.

"The recently announced Koch Institute will provide a forum to develop many such interactions among faculty members from the schools of engineering and science," he said.

####

For more information, please click here

Contacts:
77 massachusetts avenue
room 11-400
cambridge, ma 02139-4307
617-253-2700

Copyright © MIT

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Announcements

University of Manchester selects Anasys AFM-IR for coatings and corrosion research July 30th, 2014

Nature inspires a greener way to make colorful plastics July 30th, 2014

Analytical solutions from Malvern Instruments support University of Wisconsin-Milwaukee researchers in understanding environmental effects of nanomaterials July 30th, 2014

FEI Unveils New Solutions for Faster Time-to-Analysis in Metals Research July 30th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE