Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > NIH Awards Professor $3.96 Mil Grant

Michael Jay - Ph.D.
Michael Jay - Ph.D.

Abstract:
A drug therapy to protect the U.S. population from the consequences of nuclear terrorism is being pioneered by scientists at the University of Kentucky College of Pharmacy. The National Institutes of Health (NIH) awarded Michael Jay, professor of pharmaceutical sciences in the UK College of Pharmacy, $3.96 million over the next two years to develop an orally administered treatment to be used in radiation emergencies such as after exposure to radiological dispersion devices (RDDs) or dirty bombs.

NIH Awards Professor $3.96 Mil Grant

LEXINGTON, KY | Posted on November 30th, 2007

This grant comes in response to the encouraging results from Jay's initial study in 2005 for which the NIH awarded him $1.2 million. Jay and his colleagues, Robert Yokel, professor and associate dean for research and graduate education, Patrick McNamara, professor and chair of the Department of Pharmaceutical Sciences and Russ Mumper, professor and director of the Center for Nanotechnology in Drug Delivery at the University of North Carolina, began synthesizing a series of compounds and quickly focused in on one that they will continue to study in the current product development phase.

Internal exposure to radioactive material from the detonation of dirty bombs constitutes a health hazard because of the continuous emission of radioactivity to radiosensitive tissues and subsequent development of cell death, organ dysfunction and cancer. Internalization of radioactive material may occur via inhalation, ingestion or through contamination of open wounds which can be transported through the body via the blood.

The U.S. Food and Drug Administration (FDA) has determined that a drug called DTPA (diethylenetriaminepentaacetate) is safe and effective for the treatment of internal contamination. Currently, DPTA is not absorbed very well when administered orally, thus, it must be administered intravenously. The ultimate goal of Jay's study is to develop a highly bioavailable form of DTPA that can be administered orally, can be stored in the Strategic National Stockpile, is stable and has a long shelf-life, can be distributed to the at-risk population in a short period of time, can be self-administered with little risk of toxicity, and can effectively remove radioactivity from a contaminated individual. An orally bioavailable form of DTPA offers many advantages over an injectable form, such as, greater stability, less expense in manufacturing, no need for a trained professional to administer the dose and no risk of bacterial contamination.

####

For more information, please click here

Contacts:
Ann Blackford
(859) 323-6363, x230

Copyright © University of Kentucky

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Govt.-Legislation/Regulation/Funding/Policy

Surfing a wake of light: Researchers observe and control light wakes for the first time July 6th, 2015

New technology using silver may hold key to electronics advances July 2nd, 2015

NIST Group Maps Distribution of Carbon Nanotubes in Composite Materials July 2nd, 2015

Ultra-stable JILA microscopy technique tracks tiny objects for hours July 1st, 2015

Academic/Education

Oxford Instruments’ TritonXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Rice University boots up powerful microscopes: New electron microscopes will capture images at subnanometer resolution June 29th, 2015

Six top Catalan research centres constitute ‘The Barcelona Institute of Science and Technology’ to pursue a joint scientific endeavour June 27th, 2015

Lancaster University revolutionary quantum technology research receives funding boost June 22nd, 2015

Nanomedicine

A Stretchy Mesh Heater for Sore Muscles July 6th, 2015

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Iranian Scientists Find Simple, Economic Method to Synthesize Antibacterial Nanoparticles July 2nd, 2015

Announcements

Surfing a wake of light: Researchers observe and control light wakes for the first time July 6th, 2015

Tel Aviv/Tsinghua University project uses crowd computing to improve water filtration: The research, a product of the new TAU-Tsinghua XIN Center, was conducted by 150,000 volunteers at IBM's World Community Grid July 6th, 2015

Transition from 3 to 2 dimensions increases conduction, MIPT scientists discover July 6th, 2015

A Stretchy Mesh Heater for Sore Muscles July 6th, 2015

Homeland Security

Iranian Scientists Design Nano Device to Detect Cyanogen Toxic Gas June 23rd, 2015

New sensing tech could help detect diseases, fraudulent art, chemical weapons June 1st, 2015

UCLA nanoscientists are first to model atomic structures of three bacterial nanomachines: Cryo electron microscope enables scientists to explore the frontiers of targeted antibiotics April 21st, 2015

Optics, nanotechnology combined to create low-cost sensor for gases April 3rd, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

Discovery of nanotubes offers new clues about cell-to-cell communication July 2nd, 2015

World’s 1st Full-Color, Flexible, Skin-Like Display Developed at UCF June 24th, 2015

Physicists fine-tune control of agile exotic materials: Tunable hybrid polaritons realized with graphene layer on hexagonal boron nitride June 24th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project